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Browsing by Author "Dieckhoff, Britta"
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2009-04-22ZeitschriftenartikelDistribution and expression of porcine endogenous retroviruses in multi-transgenic pigs generated for xenotransplantation Dieckhoff, Britta; Kessler, Barbara; Jobst, Danny; Kues, Wilfried A.; Petersen, Björn; Pfeifer, Alexander; Kurth, Reinhard; Niemann, Heiner; Wolf, Eckhard; Denner, JoachimBackground: Multi-transgenic pigs produced for use in xenotransplantation have to be screened for the presence and expression of porcine endogenous retroviruses (PERV) to select animals with low PERV load. The production ...
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2015-04-30ZeitschriftenartikelInduction of neutralizing antibodies specific for the envelope proteins of the koala retrovirus by immunization with recombinant proteins or with DNA Fiebig, Uwe; Dieckhoff, Britta; Wurzbacher, Christian; Möller, Annekathrin; Kurth, Reinhard; Denner, JoachimBackground: The koala retrovirus (KoRV) is the result of a transspecies transmission of a gammaretrovirus with fatal consequences for the new host. Like many retroviruses, KoRV induces lymphoma, leukemia and an ...
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2008-03-10ZeitschriftenartikelKnockdown of porcine endogenous retrovirus (PERV) expression by PERV-specific shRNA in transgenic pigs Dieckhoff, Britta; Petersen, Björn; Kues, Wilfried A.; Kurth, Reinhard; Niemann, Heiner; Denner, JoachimBackground: Xenotransplantation using porcine cells, tissues or organs may be associated with the transmission of porcine endogenous retroviruses (PERVs). More than 50 viral copies have been identified in the pig genome ...
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2007-07-01DissertationXenotransplantation und porzine endogene Retroviren (PERV): Evaluierung des Risikos und Prävention der Virusübertragung Dieckhoff, BrittaDie Xenotransplantation porziner Zellen, Gewebe und Organe bietet eine Möglichkeit, den immensen Mangel an geeigneten allogenen Transplantaten zu überbrücken. Die Grundvoraussetzung ist hierbei neben der Lösung immunologischer ...