2022-12-21Zeitschriftenartikel
Genetic diversity in the metronidazole metabolism genes nitroreductases and pyruvate ferredoxin oxidoreductases in susceptible and refractory clinical samples of Giardia lamblia
Saghuag, Christina S.; Gamlem, Astrid L.; Hauge, Kirsti B.; Vahokoski, Juha; Klotz, Christian; Langeland, Nina; Hanevik, Kurt; Aebischer, Toni
The effectiveness of metronidazole against the tetraploid intestinal parasite Giardia lamblia is dependent on its
activation/inactivation within the cytoplasm. There are several activating enzymes, including pyruvate ...