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Browsing by Author "Bergström, Tomas"
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2015-11-26ZeitschriftenartikelGeneration and Characterization of Six Recombinant Botulinum Neurotoxins as Reference Material to Serve in an International Proficiency Test Weisemann, Jasmin; Krez, Nadja; Fiebig, Uwe; Worbs, Sylvia; Skiba, Martin; Endermann, Tanja; Dorner, Martin; Bergström, Tomas; Muñoz, Amalia; Zegers, Ingrid; Müller, Christian; Jenkinson, Stephen P.; Avondet, Marc-Andre; Delbrassinne, Laurence; Denayer, Sarah; Zeleny, Reinhard; Schimmel, Heinz; Åstot, Crister; Dorner, Brigitte; Rummel, AndreasThe detection and identification of botulinum neurotoxins (BoNT) is complex due to the existence of seven serotypes, derived mosaic toxins and more than 40 subtypes. Expert laboratories currently use different technical ...
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2016-06-16ZeitschriftenartikelOnly the complex N559-glycan in SV2C mediates high affinity binding to botulinum neurotoxin serotype A1 Mahrhold, Stefan; Bergström, Tomas; Stern, Daniel; Dorner, Brigitte; Astot, Crister; Rummel, AndreasThe extraordinary potency of botulinum neurotoxins (BoNTs) is mediated by their high neurospecificity, targeting peripheral cholinergic motoneurons leading to flaccid paralysis and successive respiratory failure. Complex ...