Browsing by Author "Paape, Daniel"

Now showing items 1-3 of 3

2017-03-27Zeitschriftenartikel

Changes to cholesterol trafficking in macrophages by Leishmania parasites infection

Semini, Geo; Paape, Daniel; Paterou, Athina; Schroeder, Juliane; Barrios-Llerena, Martin; Aebischer, Toni

Leishmania spp. are protozoan parasites that are transmitted by sandfly vectors during blood sucking to vertebrate hosts and cause a spectrum of diseases called leishmaniases. It has been demonstrated that host cholesterol ...
2011-05-19Zeitschriftenartikel

Contribution of proteomics of Leishmania spp. to the understanding of differentiation, drug resistance mechanisms, vaccine and drug development

Paape, Daniel; Aebischer, Toni

Leishmania spp., protozoan parasites with a digenetic life cycle, cause a spectrum of diseases in humans. Recently several Leishmania spp. have been sequenced which significantly boosted the number and quality of proteomic ...
2020-06-02Zeitschriftenartikel

Leishmania Encodes a Bacterium-like 2,4-Dienoyl-Coenzyme A Reductase That Is Required for Fatty Acid β-Oxidation and Intracellular Parasite Survival

Semini, Geo; Paape, Daniel; Blume, Martin; Sernee, M. Fleur; Peres-Alonso, Diego; Calvignac-Spencer, Sébastien; Döllinger, Jörg; Jehle, Stefan; Saunders, Eleanor; McConville, Malcolm J.; Aebischer, Toni

Leishmaniaspp. are protozoan parasites that cause a spectrum of im-portant diseases in humans. These parasites develop as extracellular promastigotesin the digestive tract of their insect vectors and as obligate intracellular ...