- edoc Startseite
- Auflistung nach Autor
Auflistung nach Autor "Hofmann, Jörg"
Anzeige der Publikationen 1-19 von 19
-
2011-02-09ZeitschriftenartikelA novel human polyomavirus closely related to the African green monkey-derived lymphotropic polyomavirus (LPV) Scuda, Nelly; Hofmann, Jörg; Calvignac, Sébastien; Ruprecht, Klemens; Liman, Peter; Kühn, Joachim; Hengel, Hartmut; Ehlers, BernhardA novel human polyomavirus was identified with generic PCR in a kidney transplant patient under immunosuppressive treatment. Its genome was completely amplified and sequenced. In phylogenetic analyses it appeared as the ...
-
2022-02-02ZeitschriftenartikelAdvanced sequencing approaches detected insertions of viral and human origin in the viral genome of chronic hepatitis E virus patients Papp, C.‑Patrick; Biedermann, Paula; Harms, Dominik; Wang, Bo; Kebelmann, Marianne; Choi, Mira; Helmuth, Johannes; Corman, Victor M.; Thürmer, Andrea; Altmann, Britta; Klink, Patrycja; Hofmann, Jörg; Bock, C.‑ThomasThe awareness of hepatitis E virus (HEV) increased significantly in the last decade due to its unexpectedly high prevalence in high-income countries. There, infections with HEV-genotype 3 (HEV-3) are predominant which can ...
-
2016-09-16ZeitschriftenartikelBrincidofovir clearance of acyclovir-resistant herpes simplex virus-1 and adenovirus infection after stem cell transplantation Voigt, Sebastian; Hofmann, Jörg; Edelmann, Anke; Sauerbrei, Andreas; Kühl, J. S.Infections with adenovirus (AdV) and herpesviruses can result in considerable morbidity and mortality in pediatric hematopoietic stem cell transplant (SCT) recipients. Herpes simplex virus (HSV) reactivations are usually ...
-
2022-03-21ZeitschriftenartikelCluster of human Puumala orthohantavirus infections due to indoor exposure?—An interdisciplinary outbreak investigation Princk, Christina; Drewes, Stephan; Meyer-Schlinkmann, Kristin M.; Saathoff, Marion; Binder, Florian; Freise, Jona; Tenner, Beate; Weiss, Sabrina; Hofmann, Jörg; Esser, Jutta; Runge, Martin; Jacob, Jens; Ulrich, Rainer G.; Dreesman, JohannesPuumala orthohantavirus (PUUV) is the most important hantavirus species in Europe, causing the majority of human hantavirus disease cases. In central and western Europe, the occurrence of human infections is mainly driven ...
-
2019-07-17ZeitschriftenartikelEpidemiology of Human Parechovirus Type 3 Upsurge in 2 Hospitals, Freiburg, Germany, 2018 Elling, Roland; Böttcher, Sindy; du Bois, Florian; Müller, Alexandra; Prifert, Christiane; Weissbrich, Benedikt; Hofmann, Jörg; Korn, Klaus; Eis-Hübinger, Anna-Maria; Hufnagel, Markus; Panning, MarcusIn 2018, a cluster of pediatric human parechovirus (HPeV) infections in 2 neighboring German hospitals was detected. Viral protein 1 sequence analysis demonstrated co-circulation of different HPeV-3 sublineages and of ...
-
2018-04-12ZeitschriftenartikelHantavirus-Infektionen in Deutschland – ein Rückblick auf das Ausbruchsjahr 2017 Neues aus dem Konsiliarlaboratorium für HantavirenHofmann, Jörg; Krüger, Detlev H.; Loyen, MartinIm Epidemiologischen Bulletin 15/2018 gibt das Konsiliarlabor für Hantaviren einen Überblick zu Hantavirus-Infektionen in Deutschland. Im Jahr 2017 hat das Robert Koch-Institut 1.713 Fälle von Hantavirus-Infektionen ...
-
2010-08-09ZeitschriftenartikelHantavirusinfektionen Massiver Anstieg an Erkrankungen in DeutschlandKrüger, Detlev H.; Hofmann, Jörg; Ulrich, Rainer; Stark, KlausDa bisher weder eine Schutzimpfung noch eine kausale antivirale Therapie gegen dieses „emerging virus“ verfügbar sind, kommt der Expositionsprophylaxe eine besondere Bedeutung zu.
-
2021-05-07ZeitschriftenartikelHepatitis E: An update on One Health and clinical medicine Velavan, Thirumalaisamy P.; Pallerla, Srinivas R.; Johne, Reimar; Todt, Daniel; Steinmann, Eike; Schemmerer, Mathias; Wenzel, Jürgen J.; Hofmann, Jörg; Shih, James Wai Kuo; Wedemeyer, Heiner; Bock, Claus-ThomasThe hepatitis E virus (HEV) is one of the main causes of acute hepatitis and the de facto global burden is underestimated. HEV-related clinical complications are often undetected and are not considered in the differential ...
-
2009-11-26ZeitschriftenartikelHigh genotypic diversity and a novel variant of human cytomegalovirus revealed by combined UL33/UL55 genotyping with broad-range PCR Deckers, Merlin; Hofmann, Jörg; Kreuzer, Karl-Anton; Reinhard, Henrike; Edubio, Abigail; Hengel, Hartmut; Voigt, Sebastian; Ehlers, BernhardThe known strains of human cytomegalovirus (HCMV) represent genotypic variants of a single species, and HCMV genotypic variability has been studied in order to reveal correlations between different disease patterns and the ...
-
2017-05-18ZeitschriftenartikelIdentification of a Novel Hepatitis E Virus Genotype 3 Strain Isolated from a Chronic Hepatitis E Virus Infection in a Kidney Transplant Recipient in Switzerland Wang, Bo; Harms, Dominik; Hofmann, Jörg; Ciardo, Diana; Kneubühl, Agnes; Bock, ThomasHepatitis E virus genotype 3 (HEV-3) is the causal pathogen of chronic hepatitis E. We report here the full-length genome sequence of an HEV-3 strain, isolated from a kidney transplant recipient in Switzerland (SW/16-0282). ...
-
2013-03-13ZeitschriftenartikelIdentification of a Novel Human Polyomavirus in Organs of the Gastrointestinal Tract Korup, Sarah; Rietscher, Janita; Calvignac-Spencer, Sébastien; Trusch, Franziska; Hofmann, Jörg; Moens, Ugo; Sauer, Igor; Voigt, Sebastian; Schmuck, Rosa; Ehlers, BernhardPolyomaviruses are small, non-enveloped viruses with a circular double-stranded DNA genome. Using a generic polyomavirus PCR targeting the VP1 major structural protein gene, a novel polyomavirus was initially identified ...
-
2010-09-27ZeitschriftenartikelImproved Detection of Mutated Human Cytomegalovirus UL97 by Pyrosequencing Schindele, Birgit; Apelt, Luise; Hofmann, Jörg; Nitsche, Andreas; Michel, Detlef; Voigt, Sebastian; Mertens, Thomas; Ehlers, BernhardGanciclovir (GCV) resistance frequently occurs upon prolonged treatment of ongoing active human cytomegalovirus (HCMV) infection in individuals with immature or compromised immune functions (e.g., recipients of solid-organ ...
-
2019-08-08ZeitschriftenartikelMolecular and epidemiological characteristics of human Puumala and Dobrava-Belgrade hantavirus infections, Germany, 2001 to 2017 Faber, Mirko; Krüger, Detlev H.; Auste, Brita; Stark, Klaus; Hofmann, Jörg; Weiss, SabrinaIntroduction Two hantavirus species, Puumala (PUUV) and Dobrava-Belgrade (DOBV) virus (genotype Kurkino), are endemic in Germany. Recent PUUV outbreaks raised questions concerning increasing frequency of outbreaks and ...
-
2019-01-31ZeitschriftenartikelMolecular Evolution of Human Adenovirus (HAdV) Species C Dhingra, Akshay; Hage, Elias; Ganzenmueller, Tina; Böttcher, Sindy; Hofmann, Jörg; Hamprecht, Klaus; Obermeier, Patrick; Rath, Barbara; Hausmann, Fabian; Dobner, Thomas; Heim, AlbertCurrently, 88 different Human Adenovirus (HAdV) types are grouped into seven HAdV species A to G. Most types (57) belong to species HAdV-D. Recombination between capsid genes (hexon, penton and fiber) is the main factor ...
-
2013-06-20ZeitschriftenartikelNovel Polyomaviruses of Nonhuman Primates: Genetic and Serological Predictors for the Existence of Multiple Unknown Polyomaviruses within the Human Population Scuda, Nelly; Madinda, Nadege Freda; Akoua-Koffi, Chantal; Adjogoua, Edgard Valerie; Wevers, Diana; Hofmann, Jörg; Cameron, Kenneth N.; Leendertz, Siv Aina J.; Couacy-Hymann, Emmanuel; Robbins, Martha; Boesch, Christophe; Jarvis, Michael A.; Moens, Ugo; Mugisha, Lawrence; Calvignac-Spencer, Sébastien; Leendertz, Fabian; Ehlers, BernhardPolyomaviruses are a family of small non-enveloped DNA viruses that encode oncogenes and have been associated, to greater or lesser extent, with human disease and cancer. Currently, twelve polyomaviruses are known to ...
-
2010-12-01ZeitschriftenartikelPandemic Influenza A (H1N1) Outbreak among 15 School-Aged HIV-1-Infected Children Feiterna-Sperling, Cornelia; Edelmann, Anke; Nickel, Renate; Magdorf, Klaus; Bergmann, Frank; Rautenberg, Peter; Schweiger, Brunhilde; Wahn, Volker; Krüger, Detlev H.; Hofmann, JörgPatients infected with human immunodeficiency virus type 1 (HIV-1) are considered to be at increased risk for 2009 H1N1 influenza-related complications. We performed an observational study after an outbreak of 2009 H1N1 ...
-
2012-01-04ZeitschriftenartikelSeroprevalence of human polyomavirus 9 and cross-reactivity to African green monkey-derived lymphotropic polyomavirus Trusch, Franziska; Klein, Marcus; Finsterbusch, Tim; Kühn, Joachim; Hofmann, Jörg; Ehlers, BernhardHuman polyomavirus 9 (HPyV9) was discovered recently in immunocompromised patients and shown to be genetically closely related to B-lymphotropic polyomavirus (LPyV). No serological data are available for HPyV9, but human ...
-
2020-03-24ZeitschriftenartikelSpecific circulating microRNAs during hepatitis E infection can serve as indicator for chronic hepatitis E Harms, Dominik; Choi, Mira; Allers, Kristina; Wang, Bo; Pietsch, Heiko; Papp, C.-Patrick; Hanisch, Lina; Kurreck, Jens; Hofmann, Jörg; Bock, C.-ThomasHepatitis E virus (HEV) genotypes 3 and 4 (HEV-3, HEV-4) infections are an emerging public health issue in industrialized countries. HEV-3 and −4 are usually self-limiting but can progress to chronic hepatitis E in ...
-
2017-01-26ZeitschriftenartikelSteep rise in norovirus cases and emergence of a new recombinant strain GII.P16-GII.2, Germany, winter 2016 Niendorf, Sandra; Jacobsen, Sonja; Faber, Mirko; Eis-Hübinger, A. M.; Hofmann, Jörg; Zimmermann, Ortrud; Höhne, Marina; Bock, ThomasSince early November 2016, the number of laboratory-confirmed norovirus infections reported in Germany has been increasing steeply. Here, we report the detection and genetic characterisation of an emerging norovirus ...