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Auflistung nach Autor "Hartung, Evelyn"
Anzeige der Publikationen 1-6 von 6
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2013-10-23ZeitschriftenartikelCytomegalovirus expresses the chemokine homologue vXCL1 capable of attracting XCR1+CD4- dendritic cells Geyer, Henriette; Hartung, Evelyn; Mages, Hans Werner; Weise, Christoph; Belužić, Robert; Vugrek, Oliver; Jonjić, Stipan; Kroczek, Richard; Voigt, SebastianCytomegaloviruses (CMV) have developed various strategies to escape the immune system of the host. One strategy involves the expression of virus-encoded chemokines to modulate the host chemokine network. We have identified ...
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2012-07-18ZeitschriftenartikelExpression of XCR1 characterizes the Batf3-dependent lineage of dendritic cells capable of antigen cross-presentation Bachem, Annabell; Hartung, Evelyn; Güttler, Steffen; Mora, Ahmed; Zhou, Xuefei; Hegemann, Anika; Plantinga, Maud; Mazzini, Elisa; Stoitzner, Patrizia; Gurka, Stephanie; Henn, Volker; Mages, Hans Werner; Kroczek, RichardCross-presentation of antigen by dendritic cells (DCs) to CD8+ T cells is a fundamentally important mechanism in the defense against pathogens and tumors. Due to the lack of an appropriate lineage marker, cross-presenting ...
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2015-02-04ZeitschriftenartikelMouse conventional dendritic cells can be universally classified based on the mutually exclusive expression of XCR1 and SIRPα Gurka, Stephanie; Hartung, Evelyn; Becker, Martina; Kroczek, RichardSince the identification of mouse dendritic cells (DC) in the early 70s, all attempts to consistently classify the identified functional DC subpopulations according to their surface molecule expression failed. In the absence ...
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2014-07-28ZeitschriftenartikelOntogenic, phenotypic, and functional characterization of XCR1+ dendritic cells leads to a consistent classification of intestinal dendritic cells based on the expression of XCR1 and SIRPα Becker, Martina; Güttler, Steffen; Bachem, Annabell; Hartung, Evelyn; Mora, Ahmed; Jäkel, Anika; Hutloff, Andreas; Henn, Volker; Mages, Hans Werner; Gurka, Stephanie; Kroczek, RichardIn the past, lack of lineage markers confounded the classification of dendritic cells (DC) in the intestine and impeded a full understanding of their location and function. We have recently shown that the chemokine receptor ...
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2018-12-13ZeitschriftenartikelStructure-Function Relationship of XCL1 Used for in vivo Targeting of Antigen Into XCR1+ Dendritic Cells Kroczek, Arthur L.; Hartung, Evelyn; Gurka, Stephanie; Becker, Martina; Reeg, Nele; Mages, Hans Werner; Voigt, Sebastian; Freund, Christian; Kroczek, RichardXCL1 is the ligand for XCR1, a chemokine receptor uniquely expressed on crosspresenting dendritic cells (DC) in mouse and man. We are interested in establishing therapeutic vaccines based on XCL1-mediated targeting of ...
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2010-05-17ZeitschriftenartikelSuperior antigen cross-presentation and XCR1 expression define human CD11c+CD141+ cells as homologues of mouse CD8+ dendritic cells Bachem, Annabell; Güttler, Steffen; Hartung, Evelyn; Ebstein, Frédéric; Schaefer, Michael; Tannert, Astrid; Salama, Abdulgabar; Movassaghi, Kamran; Opitz, Corinna; Mages, Hans Werner; Henn, Volker; Kloetzel, Peter-Michael; Gurka, Stephanie; Kroczek, RichardIn recent years, human dendritic cells (DCs) could be subdivided into CD304+ plasmacytoid DCs (pDCs) and conventional DCs (cDCs), the latter encompassing the CD1c+, CD16+, and CD141+ DC subsets. To date, the low frequency ...