2011-06-01Zeitschriftenartikel
RNA helicase retinoic acid-inducible gene I as a sensor of Hantaan virus replication
Lee, Min-Hi; Lalwani, Pritesh; Raftery, Martin J.; Matthaei, Markus; Lütteke, Nina; Kirsanovs, Sina; Binder, Marco; Ulrich, Rainer G.; Giese, Thomas; Wolff, Thorsten; Krüger, Detlev H.; Schönrich, Günther
Hantaan virus (HTNV) causes severe human disease. The HTNV genome consists of three ssRNA segments of negative polarity that are complexed with viral nucleocapsid (N) protein. How the human innate immune system detects ...