Browsing by Author "Ignatova, Zoya"

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2021-06-14Zeitschriftenartikel

smORFer: a modular algorithm to detect small ORFs in prokaryotes

Bartholomäus, Alexander; Kolte, Baban; Mustafayeva, Ayten; Goebel, Ingrid; Fuchs, Stephan; Benndorf, Dirk; Engelmann, Susanne; Ignatova, Zoya

Emerging evidence places small proteins (≤50 amino acids) more centrally in physiological processes. Yet, their functional identification and the systematic genome annotation of their cognate small open-reading frames ...
2021-06-01Zeitschriftenartikel

Towards the characterization of the hidden world of small proteins in Staphylococcus aureus, a proteogenomics approach

Fuchs, Stephan; Kucklick, Martin; Lehmann, Erik; Beckmann, Alexander; Wilkens, Maya; Kolte, Baban; Mustafayeva, Ayten; Ludwig, Tobias; Diwo, Maurice; Wissing, Josef; Jänsch, Lothar; Ahrens, Christian H.; Ignatova, Zoya; Engelmann, Susanne

Small proteins play essential roles in bacterial physiology and virulence, however, automated algorithms for genome annotation are often not yet able to accurately predict the corresponding genes. The accuracy and reliability ...