2021-01-25Zeitschriftenartikel
Asymptomatic Infection of Marburg Virus Reservoir Bats Is Explained by a Strategy of Immunoprotective Disease Tolerance
Guito, Jonathan C.; Prescott, Joseph B.; Arnold, Catherine E.; Amman, Brian R.; Schuh, Amy J.; Spengler, Jessica R.; Sealy, Tara K.; Harmon, Jessica R.; Coleman-McCray, JoAnn D.; Kulcsar, Kirsten A.; Nagle, Elyse R.; Kumar, Raina; Palacios, Gustavo; Sanchez-Lockhart, Mariano; Towner, Jonathan S.
Marburg virus (MARV) is among the most virulent pathogens of primates, including humans. Contributors to severe MARV disease include immune response suppression and inflammatory gene dysregulation (“cytokine storm”), leading ...