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Auflistung nach Autor "Holland, Gudrun"
Anzeige der Publikationen 1-14 von 14
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2009-05-01ZeitschriftenartikelbdhA-patD operon as a virulence determinant, revealed by a novel large-scale approach for identification of Legionella pneumophila mutants defective for amoeba infection. Aurass, Philipp; Pless, Birgit; Rydzewski, Kerstin; Holland, Gudrun; Bannert, Norbert; Flieger, AntjeLegionella pneumophila, the causative agent of Legionnaires' disease, is an intracellular parasite of eukaryotic cells. In the environment, it colonizes amoebae. After being inhaled into the human lung, the bacteria infect ...
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2021-02-20ZeitschriftenartikelFirst Description of a Temperate Bacteriophage (vB_FhiM_KIRK) of Francisella hispaniensis Strain 3523 Köppen, Kristin; Prensa, Grisna I.; Rydzewski, Kerstin; Tlapák, Hana; Holland, Gudrun; Heuner, KlausHere we present the characterization of a Francisella bacteriophage (vB_FhiM_KIRK) including the morphology, the genome sequence and the induction of the prophage. The prophage sequence (FhaGI-1) has previously been ...
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2012-08-05ZeitschriftenartikelFliA expression analysis and influence of the regulatory proteins RpoN, FleQ and FliA on virulence and in vivo fitness in Legionella pneumophila Schulz, Tino; Rydzewski, Kerstin; Schunder, Eva; Holland, Gudrun; Bannert, Norbert; Heuner, KlausIn Legionella pneumophila, the regulation of the flagellum and the expression of virulence traits are linked. FleQ, RpoN and FliA are the major regulators of the flagellar regulon. We demonstrated here that all three ...
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2014-06-25ZeitschriftenartikelGenome sequence and phenotypic analysis of a first German Francisella sp. isolate (W12-1067) not belonging to the species Francisella tularensis Rydzewski, Kerstin; Schulz, Tino; Brzuszkiewicz, Elzbieta; Holland, Gudrun; Lück, Christian; Fleischer, Jens; Grunow, Roland; Heuner, KlausBackground: Francisella isolates from patients suffering from tularemia in Germany are generally strains of the species F. tularensis subsp. holarctica. To our knowledge, no other Francisella species are known for ...
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2011-02-16ZeitschriftenartikelHighly conserved serine residue 40 in HIV-1 p6 regulates capsid processing and virus core assembly Votteler, Jörg; Neumann, Liane; Hahn, Sabine; Hahn, Friedrich; Rauch, Pia; Schmidt, Kerstin; Studtrucker, Nicole; Solbak, Sara MØ; Fossen, Torgils; Henklein, Peter; Ott, David E.; Holland, Gudrun; Bannert, Norbert; Schubert, UlrichBackground: The HIV-1 p6 Gag protein regulates the final abscission step of nascent virions from the cell membrane by the action of two late assembly (L-) domains. Although p6 is located within one of the most polymorphic ...
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2016-03-02ZeitschriftenartikelIntestinal Cell Tight Junctions Limit Invasion of Candida albicans through Active Penetration and Endocytosis in the Early Stages of the Interaction of the Fungus with the Intestinal Barrier Goyer, Marianne; Loiselet, Alicia; Bon, Fabienne; L’Ollivier, Coralie; Laue, Michael; Holland, Gudrun; Bonnin, Alain; Dalle, FredericC. albicans is a commensal yeast of the mucous membranes in healthy humans that can also cause disseminated candidiasis, mainly originating from the digestive tract, in vulnerable patients. It is necessary to understand ...
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2013-07-18ZeitschriftenartikelLegionella oakridgensis ATCC 33761 genome sequence and phenotypic characterization reveals its replication capacity in amoebae Brzuszkiewicz, Elzbieta; Schulz, Tino; Rydzewski, Kerstin; Daniel, Rolf; Gillmaier, Nadine; Dittmann, Christine; Holland, Gudrun; Schunder, Eva; Lautner, Monika; Eisenreich, Wolfgang; Lück, Christian; Heuner, KlausLegionella oakridgensis is able to cause Legionnaires’ disease, but is less virulent compared to L. pneumophila strains and very rarely associated with human disease. L. oakridgensis is the only species of the family ...
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2011-02-10ZeitschriftenartikelMechanical damage to Gram-negative bacteria by surface plating with the Drigalski-spatula technique Hedderich, Reiner; Müller, Rolf; Greulich, Yasmin; Bannert, Norbert; Holland, Gudrun; Kaiser, Petra; Reissbrodt, RolfColony counting by spreading bacterial suspensions on plating media by various techniques is of general concern. Comparative studies between hand plating (Drigalski-spatula technique) for different time intervals and spiral ...
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2010-06-21ZeitschriftenartikelMicrotubes self-assembled from a cholesterol-modified nucleoside Pescador, Paula; Brodersen, Nicolai; Scheidt, Holger A.; Loew, Martin; Holland, Gudrun; Bannert, Norbert; Liebscher, Jürgen; Herrmann, Andreas; Huster, Daniel; Arbuzova, AnnaWe describe the formation of lipid microtubes from a novel cholesterol-modified nucleoside in binary mixture with phospholipids. Stable cylindrical structures with an outer diameter of 2–3 μm and a length of 20–40 μm were ...
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2018-12-05ZeitschriftenartikelNovel type of pilus associated with a Shiga-toxigenic E. coli hybrid pathovar conveys aggregative adherence and bacterial virulence Lang, Christina; Fruth, Angelika; Holland, Gudrun; Laue, Michael; Mühlen, Sabrina; Dersch, Petra; Flieger, AntjeA large German outbreak in 2011 was caused by a locus of enterocyte effacement (LEE)-negative enterohemorrhagic E. coli (EHEC) strain of the serotype O104:H4. This strain harbors markers that are characteristic of both ...
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2009-12-18ZeitschriftenartikelOrbus hercynius gen. nov., sp. nov., isolated from faeces of wild boar, is most related to Enterobacteriales and Pasteurellales Volkmann, Maria; Skiebe, Evelyn; Kerrinnes, Tobias; Faber, Franziska; Lepka, Daniela; Pfeifer, Yvonne; Holland, Gudrun; Bannert, Norbert; Wilharm, GottfriedA novel gammaproteobacterium, strain CN3T, was isolated from faeces of wild boar. It is facultative anaerobic and appears coccoid or rod shaped. The determined partial 16S rRNA gene sequence of strain CN3T suggests a distant ...
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2014-12-05ZeitschriftenartikelSelf-assembly of a cholesteryl-modified nucleoside into tubular structures from giant unilamellar vesicles Losensky, Luisa; Chiantia, Salvatore; Holland, Gudrun; Laue, Michael; Petran, Anca; Liebscher, Jürgen; Arbuzova, AnnaWe recently reported the formation of micro- and nanometer thick tubules in a binary system of cholesteryl-modified aminouridine and a phosphatidylcholine in aqueous solution upon cooling from 70 °C to room temperature ...
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2022-03-16ZeitschriftenartikelUltrastructural examination of lung “cryobiopsies” from a series of fatal COVID-19 cases hardly revealed infected cells Cortese, Katia; Holland, Gudrun; Möller, Lars; Gagliani, Maria Cristina; Barisione, Emanuela; Ball, Lorenzo; Pelosi, Paolo; Grillo, Federica; Mastracci, Luca; Fiocca, Roberto; Laue, MichaelUltrastructural analysis of autopsy samples from COVID-19 patients usually suffers from significant structural impairment possibly caused by the rather long latency between death of the patient and an appropriate sample ...
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2021-01-14ZeitschriftenartikelUsing EM data to understand COVID-19 pathophysiology – Authors' reply Dittmayer, Carsten; Meinhardt, Jenny; Radbruch, Helena; Radke, Josefine; Heppner, Barbara Ingold; Heppner, Frank L; Stenzel, Werner; Holland, Gudrun; Laue, Michael