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Browsing by Author "Aurass, Philipp"
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2009-05-01ZeitschriftenartikelbdhA-patD operon as a virulence determinant, revealed by a novel large-scale approach for identification of Legionella pneumophila mutants defective for amoeba infection. Aurass, Philipp; Pless, Birgit; Rydzewski, Kerstin; Holland, Gudrun; Bannert, Norbert; Flieger, AntjeLegionella pneumophila, the causative agent of Legionnaires' disease, is an intracellular parasite of eukaryotic cells. In the environment, it colonizes amoebae. After being inhaled into the human lung, the bacteria infect ...
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2015-04-02ZeitschriftenartikelComparative Genomic Analysis of Two Novel Sporadic Shiga Toxin-Producing Escherichia coli O104:H4 Strains Isolated 2011 in Germany Tietze, Erhard; Dabrowski, Piotr Wojtek; Prager, Rita; Radonić, Aleksandar; Fruth, Angelika; Aurass, Philipp; Nitsche, Andreas; Mielke, Martin; Flieger, AntjeA large outbreak of gastrointestinal disease occurred in 2011 in Germany which resulted in almost 4000 patients with acute gastroenteritis or hemorrhagic colitis, 855 cases of a hemolytic uremic syndrome and 53 deaths. The ...
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2011-09-27ZeitschriftenartikelEHEC/EAEC O104:H4 strain linked with the 2011 German outbreak of haemolytic uremic syndrome enters into the viable but non-culturable state in response to various stresses and resuscitates upon stress relief Aurass, Philipp; Prager, Rita; Flieger, AntjeVarious non-spore forming bacteria, including Escherichia coli, enter a dormant-like state, the viable but non-culturable (VBNC) state, characterized by the presence of viable cells but the inability to grow on routine ...
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2017-06-08ZeitschriftenartikelGenome Sequence of Paracoccus contaminans LMG 29738T, Isolated from a Water Microcosm Aurass, Philipp; Karste, Susanne; Trost, Eva; Glaeser, Stefanie P.; Kämpfer, Peter; Flieger, AntjeWe announce here the complete genome sequence of Paracoccus contaminans LMG 29738T, which we recently isolated from a contaminated water microcosm. The genome consists of a 2.94-Mb chromosome and a 94-kb plasmid. To our ...
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2021-11-02ZeitschriftenartikelSdhA blocks disruption of the Legionella-containing vacuole by hijacking the OCRL phosphatase Choi, Won Young; Kim, Seongok; Aurass, Philipp; Huo, Wenwen; Creasey, Elizabeth A.; Edwards, Marc; Lowe, Martin; Isberg, Ralph R.Legionella pneumophila grows intracellularly within a replication vacuole via action of Icm/Dot-secreted proteins. One such protein, SdhA, maintains the integrity of the vacuolar membrane, thereby preventing cytoplasmic ...
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2014-04-21ZeitschriftenartikelTwo Novel EHEC/EAEC Hybrid Strains Isolated from Human Infections Prager, Rita; Lang, Christina; Aurass, Philipp; Fruth, Angelika; Tietze, Erhard; Flieger, AntjeThe so far highest number of life-threatening hemolytic uremic syndrome was associated with a food-borne outbreak in 2011 in Germany which was caused by an enterohemorrhagic Escherichia coli (EHEC) of the rare serotype ...