Browsing by Author "Obermeier, Patrick E."

Now showing items 1-10 of 10

2024-05-23Zeitschriftenartikel

Closing the Diagnostic Gap in Encephalitis and Acute Disseminated Encephalomyelitis through Digital Case Classification and Viral Metagenomics

Obermeier, Patrick E.; Ma, Xiaolin; Heim, Albert; Rath, Barbara A.

Encephalitis and acute disseminated encephalomyelitis (ADEM) are often caused or triggered by viruses—but the specific pathogen commonly remains unidentified in routine care. We explored the use of viral metagenomic ...
2024-03-26Zeitschriftenartikel

Disease Burden and Inpatient Management of Children with Acute Respiratory Viral Infections during the Pre-COVID Era in Germany: A Cost-of-Illness Study

Alchikh, Maren; Conrad, Tim O. F.; Obermeier, Patrick E.; Ma, Xiaolin; Schweiger, Brunhilde; Opota, Onya; Rath, Barbara A.

Respiratory viral infections (RVIs) are common reasons for healthcare consultations. The inpatient management of RVIs consumes significant resources. From 2009 to 2014, we assessed the costs of RVI management in 4776 ...
2017-02-23Zeitschriftenartikel

Genome Sequence of Novel Human Parechovirus Type 17

Böttcher, Sindy; Obermeier, Patrick E.; Diedrich, Sabine; Kaboré, Yolande; D’Alfonso, Rossella; Pfister, Herbert; Kaiser, Rolf; Cristanziano, Veronica Di

Human parechoviruses (HPeV) circulate worldwide, causing a broad variety of symptoms, preferentially in early childhood. We report here the nearly complete genome sequence of a novel HPeV type, consisting of 7,062 nucleotides ...
2022-03-14Zeitschriftenartikel

Incidence, Disease Severity, and Follow-Up of Influenza A/A, A/B, and B/B Virus Dual Infections in Children: A Hospital-Based Digital Surveillance Program

Obermeier, Patrick E.; Seeber, Lea D.; Alchikh, Maren; Schweiger, Brunhilde; Rath, Barbara A.

Influenza virus (IV) coinfection, i.e., simultaneous infection with IV and other viruses, is a common occurrence in humans. However, little is known about the incidence and clinical impact of coinfection with two different ...
2022-05-20Zeitschriftenartikel

Linking digital surveillance and in-depth virology to study clinical patterns of viral respiratory infections in vulnerable patient populations

Obermeier, Patrick E.; Heim, Albert; Biere, Barbara; Hage, Elias; Alchikh, Maren; Conrad, Tim; Schweiger, Brunhilde; Rath, Barbara A.

To improve the identification and management of viral respiratory infections, we established a clinical and virologic surveillance program for pediatric patients fulfilling pre-defined case criteria of influenza-like illness ...
2024-01-11Zeitschriftenartikel

Pockenvirusinfektionen in der Dermatologie

Obermeier, Patrick E.; Buder, Susanne C.; Hillen, Uwe

Die Familie Poxviridae umfasst derzeit 22 Gattungen, die Wirbeltiere infizieren können. Humanpathogene Pockenviren gehören den Gattungen Ortho-, Para-, Mollusci- und Yatapoxvirus an. Bis zur Eradikation der Variola vera ...
2023-12-12Zeitschriftenartikel

Poxvirus infections in dermatology – the neglected, the notable, and the notorious

Obermeier, Patrick E.; Buder, Susanne C.; Hillen, Uwe

The family Poxviridae currently comprises 22 genera that infect vertebrates. Of these, members of the Ortho-, Para-, Mollusci- and Yatapoxvirus genera have been associated with human diseases of high clinical relevance in ...
2016-09-19Zeitschriftenartikel

Recombinant Enterovirus A71 Subgenogroup C1 Strains, Germany, 2015

Böttcher, Sindy; Obermeier, Patrick E.; Neubauer, Katrin; Diedrich, Sabine
2024-06-18Zeitschriftenartikel

Reemergence of Clade IIb–Associated Mpox, Germany, July–December 2023

Obermeier, Patrick E.; Plinke, Clarissa F.; Brinkmann, Annika; Lachmann, Raskit; Melchert, Julia; Corman, Victor M.; Nitsche, Andreas; Marcus, Ulrich; Schmidt, Axel J.; Jansen, Klaus; Buder, Susanne C.

In July 2023, clade IIb–associated mpox reemerged in Germany at low levels, mainly affecting men who have sex with men. We report a representative case and phylogeny of available genome sequences. Our findings underscore ...
2023-01-07Zeitschriftenartikel

Successful Treatment of Complicated Influenza A(H3N2) Virus Infection and Rhabdomyolysis with Compassionate Use of IV Zanamivir

Alchikh, Maren; Obermeier, Patrick E.; Schweiger, Brunhilde; Rath, Barbara A.

In 2019, EMA licensed intravenous (IV) zanamivir for severe influenza virus infection in children over 6 months as well as adults. Prior to that, it was possible via a compassionate use program. We present successful ...