2023-01-18Zeitschriftenartikel
Crystal structures of OrfX1, OrfX2 and the OrfX1–OrfX3 complex from the orfX gene cluster of botulinum neurotoxin E1
Gao, Linfeng; Lam, Kwok-ho; Liu, Shun; Przykopanski, Adina; Lübke, Johanna; Qi, Ruifeng; Krüger, Maren; Nowakowska, Maria B.; Selby, Katja; Douillard, François P.; Dorner, Martin B.; Perry, Kay; Linström, Miia; Dorner, Brigitte G.; Rummel, Andreas; Jin, Rongsheng
Botulinum neurotoxins (BoNTs) are among the most lethal toxins known to humans, comprising seven established serotypes termed BoNT/A–G encoded in two types of gene clusters (ha and orfX) in BoNT-producing clostridia. The ...