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Browsing by Author "Abt, Marion"
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2011-05-31ZeitschriftenartikelImprovement of H5N1 influenza vaccine viruses: Influence of internal gene segments of avian and human origin on production and hemagglutinin content Abt, Marion; Jonge, Jørgen de; Laue, Michael; Wolff, ThorstenThe H5N1-clade 1 influenza vaccine strain NIBRG-14 produces exceptionally low amounts of antigen, a problem recently encountered also for initial pandemic H1N1-2009 vaccine seeds. Here, we report on a strategy that may ...
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2011-11-18ZeitschriftenartikelSynergistic Adaptive Mutations in the Hemagglutinin and Polymerase Acidic Protein Lead to Increased Virulence of Pandemic 2009 H1N1 Influenza A Virus in Mice Seyer, Roman; Hrincius, Eike R.; Ritzel, Dorothea; Abt, Marion; Mellmann, Alexander; Marjuki, Henju; Kühn, Joachim; Wolff, Thorsten; Ludwig, Stephan; Ehrhardt, ChristinaInfluenza impressively reflects the paradigm of a viral disease in which continued evolution of the virus is of paramount importance for annual epidemics and occasional pandemics in humans. Because of the continuous threat ...