- edoc-Server Home
- Browsing by Author
Browsing by Author "Holtfreter, Silva"
Now showing items 1-5 of 5
-
2018-10-22ZeitschriftenartikelBringing together what belongs together: Optimizing murine infection models by using mouse-adapted Staphylococcus aureus strains Trübe, Patricia; Hertlein, Tobias; Mrochen, Daniel M.; Schulz, Daniel; Jorde, Ilka; Krause, Bettina; Zeun, Julia; Fischer, Stefan; Wolf, Silver A.; Walther, Birgit; Semmler, Torsten; Bröker, Barbara M.; Ulrich, Rainer G.; Ohlsen, Knut; Holtfreter, SilvaStaphylococcus (S.) aureus is a leading cause of bacterial infection world-wide, and currently no vaccine is available for humans. Vaccine development relies heavily on clinically relevant infection models. However, the ...
-
2020-01-24ZeitschriftenartikelMolecular Epidemiology of Methicillin-Susceptible and Methicillin-Resistant Staphylococcus aureus in Wild, Captive and Laboratory Rats: Effect of Habitat on the Nasal S. aureus Population Raafat, Dina; Mrochen, Daniel M.; Al'Sholui, Fawaz; Heuser, Elisa; Ryll, René; Pritchett-Corning, Kathleen R.; Jacob, Jens; Walther, Bernd; Matuschka, Franz-Rainer; Richter, Dania; Westerhüs, Uta; Pikula, Jiri; van den Brandt, Jens; Nicklas, Werner; Monecke, Stefan; Strommenger, Birgit; van Alen, Sarah; Becker, Karsten; Ulrich, Rainer G.; Holtfreter, SilvaRats are a reservoir of human- and livestock-associated methicillin-resistant Staphylococcus aureus (MRSA). However, the composition of the natural S. aureus population in wild and laboratory rats is largely unknown. Here, ...
-
2013-03-07ZeitschriftenartikelSubpopulations of Staphylococcus aureus Clonal Complex 121 Are Associated with Distinct Clinical Entities Kurt, Kevin; Rasigade, Jean-Philippe; Laurent, Frederic; Goering, Richard V.; Zemličková, Helena; Machova, Ivana; Struelens, Marc J.; Zautner, Andreas E.; Holtfreter, Silva; Bröker, Barbara; Ritchie, Stephen; Reaksmey, Sin; Limmathurotsakul, Direk; Peacock, Sharon J.; Cuny, Christiane; Layer, Franziska; Witte, Wolfgang; Nübel, UlrichWe investigated the population structure of Staphylococcus aureus clonal complex CC121 by mutation discovery at 115 genetic housekeeping loci from each of 154 isolates, sampled on five continents between 1953 and 2009. In ...
-
2019-07-22ZeitschriftenartikelSusceptibility of livestock-associated methicillin-resistant Staphylococcus aureus (LA-MRSA) to chlorhexidine digluconate, octenidine dihydrochloride, polyhexanide, PVP-iodine and triclosan in comparison to hospital-acquired MRSA (HA-MRSA) and community-aquired MRSA (CA-MRSA): a standardized comparison Dittmann, Kathleen; Schmidt, Thomas; Müller, Gerald; Cuny, Christiane; Holtfreter, Silva; Troitzsch, Daniel; Pfaff, Peter; Hübner, Nils-OlafBackground Recent publications have raised concerns of reduced susceptibilities of clinical bacterial isolates towards biocides. This study presents a comparative investigation of the susceptibility of livestock-associated ...
-
2017-09-22ZeitschriftenartikelWild rodents and shrews are natural hosts of Staphylococcus aureus Mrochen, Daniel M.; Schulz, Daniel; Fischer, Stefan; Jeske, Kathrin; El Gohary, Heba; Reil, Daniela; Imholt, Christian; Trübe, Patricia; Suchomel, Josef; Tricaud, Emilie; Jacob, Jens; Heroldová, Marta; Bröker, Barbara M.; Strommenger, Birgit; Walther, Birgit; Ulrich, Rainer G.; Holtfreter, SilvaLaboratory mice are the most commonly used animal model for Staphylococcus aureus infection studies. We have previously shown that laboratory mice from global vendors are frequently colonized with S. aureus. Laboratory ...