Browsing by Author "Paki, Katharina"

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2019-12-04Zeitschriftenartikel

The dynamic proteome of influenza A virus infection identifies M segment splicing as a host range determinant

Bogdanow, Boris; Wang, Xi; Eichelbaum, Katrin; Sadewasser, Anne; Husic, Immanuel; Paki, Katharina; Budt, Matthias; Hergeselle, Martha; Vetter, Barbara; Hou, Jingyi; Chen, Wei; Wiebusch, Lüder; Meyer, Irmtraud M.; Wolff, Thorsten; Selbach, Matthias

Pandemic influenza A virus (IAV) outbreaks occur when strains from animal reservoirs acquire the ability to infect and spread among humans. The molecular basis of this species barrier is incompletely understood. Here we ...
2018-06-26Zeitschriftenartikel

The RNA Helicase DDX6 Associates with RIG-I to Augment Induction of Antiviral Signaling

Núñez, Rocío Daviña; Budt, Matthias; Saenger, Sandra; Paki, Katharina; Arnold, Ulrike; Sadewasser, Anne; Wolff, Thorsten

Virus infections induce sensitive antiviral responses within the host cell. The RNA helicase retinoic acid-inducible gene I (RIG-I) is a key sensor of influenza virus RNA that induces the expression of antiviral type I ...