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2015-10-20ZeitschriftenartikelBackground Paper for the update of meningococcal vaccination recommendations in Germany: use of the serogroup B vaccine in persons at increased risk for meningococcal disease In December 2013 Bexsero® became available in Germany for vaccination against serogroup B meningococci (MenB). In August 2015 the German Standing Committee on Vaccination (STIKO) endorsed a recommendation for use of this ...
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2016-01-11ZeitschriftenartikelWie werden die Impfempfehlungen gegen saisonale Influenza und gegen humane Papillomaviren in gynäkologischen Praxen umgesetzt? In Deutschland ist die Impfung gegen saisonale Influenza bei Schwangeren seit 2010 und die gegen humane Papillomaviren (HPV) bei Mädchen seit 2007 empfohlen. Niedergelassene Gynäkologinnen und Gynäkologen nehmen bei der ...
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2015-10-24ZeitschriftenartikelPrevalence and correlates of DSM-IV-TR major depressive disorder, self-reported diagnosed depression and current depressive symptoms among adults in Germany Background: While standardized diagnostic interviews using established criteria are the gold standard for assessing depression, less time consuming measures of depression and depressive symptoms are commonly used in ...
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2014-03-18ZeitschriftenartikelPre- and Post-Processing Workflow for Affinity Purification Mass Spectrometry Data The reliable detection of protein–protein interactions by affinity purification mass spectrometry (AP-MS) is crucial for the understanding of biological processes. Quantitative information can be used to separate truly ...
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2016-12-30ZeitschriftenartikelAdequate immune response ensured by binary IL-2 and graded CD25 expression in a murine transfer model The IL-2/IL-2Ralpha (CD25) axis is of central importance for the interplay of effector and regulatory T cells. Nevertheless, the question how different antigen loads are translated into appropriate IL-2 production to ensure ...
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2017-01-05ZeitschriftenartikelImplementation of the WHO multimodal Hand Hygiene Improvement Strategy in a University Hospital in Central Ethiopia Background: The burden of health-care associated infections in low-income countries is high. Adequate hand hygiene is considered the most effective measure to reduce the transmission of nosocomial pathogens. We aimed ...
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2017-01-04ZeitschriftenartikelPaPrBaG: A machine learning approach for the detection of novel pathogens from NGS data The reliable detection of novel bacterial pathogens from next-generation sequencing data is a key challenge for microbial diagnostics. Current computational tools usually rely on sequence similarity and often fail to detect ...
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2016-11-18ZeitschriftenartikelEstimation of influenza-attributable medically attended acute respiratory illness by influenza type/subtype and age, Germany, 2001/02–2014/15 Background: The total burden of influenza in primary care is difficult to assess. The case definition of medically attended “acute respiratory infection” (MAARI) in the German physician sentinel is sensitive; however, ...
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2017-01-12ZeitschriftenartikelFachliche Anwendungshinweise zur Masern-Postexpositionsprophylaxe bei Risikopersonen Bei der Gabe von Immunglobulinen zur Verhinderung von Masern handelt es sich um eine Notfallmaßnahme. Sie ist indiziert für ungeschützte Personen mit hohem Komplikationsrisiko, für die eine aktive Immunisierung kontraindiziert ...
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2017-01-12ZeitschriftenartikelEffective Detection of Porcine Cytomegalovirus Using Non-Invasively Taken Samples from Piglets Shortage of human organs forced the development of xenotransplantation using cells, tissues, and organs from pigs. Xenotransplantation may be associated with the transmission of porcine zoonotic microorganisms, among them ...
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2017-01-05ZeitschriftenartikelImpfquoten der Rotavirus-, Masern-, HPV- und Influenza- Impfung in Deutschland Aktuelle und belastbare Daten zum Impfstatus der Bevölkerung sind für die zielgruppenspezifische Kommunikation zu Impfungen und zur Evaluation von Impfempfehlungen und Impfprogrammen unerlässlich. Als einzige dauerhafte ...
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2016-12-17ZeitschriftenartikelGemeinsamer nationaler Bericht des BVL und RKI zu lebensmittelbedingten Krankheitsausbrüchen in Deutschland, 2015 In Deutschland werden jedes Jahr Hunderte von Krankheitsausbrüchen registriert, die über mikrobiell kontaminierte Lebensmittel verursacht wurden. Die Daten zu lebensmittelbedingten Ausbrüchen werden von den Gesundheits- ...
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2016-12-07ZeitschriftenartikelCD4-cell counts and presence of AIDS in HIV-positive patients entering specialized care—a comparison of migrant groups in the German ClinSurv HIV Cohort Study, 1999–2013 Background: Although early presentation to HIV-care is essential to ensure timely initiation of antiretroviral therapy, recent studies have shown that especially migrants present to HIV-care at a later stage of ...
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2017-01-06ZeitschriftenartikelEffectiveness of the 23-Valent Pneumococcal Polysaccharide Vaccine (PPV23) against Pneumococcal Disease in the Elderly: Systematic Review and Meta-Analysis Background: Routine vaccination of elderly people against pneumococcal diseases is recommended in many countries. National guidelines differ, recommending either the 23-valent polysaccharide vaccine (PPV23), the 13-valent ...
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2016-12-02ZeitschriftenartikelBluthochdruck in Deutschland Daten aus sieben bevölkerungsbasierten epidemiologischen Studien (1994–2012)Hintergrund: Bluthochdruck ist ein zentraler Risikofaktor. In Deutschland gibt es wenige bevölkerungsbezogene Datenerhebungen, die auf standardisierten Blutdruckmessungen beruhen. Methode: Es wurden standardisierte ...
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2016-11-22ZeitschriftenartikelRecent Progress in Xenotransplantation, with Emphasis on Virological Safety Xenotransplantation is a new technology that may help to overcome the shortage of human tissues and organs available for the treatment of tissue and organ failure. Remarkable progress has recently been made in this field. ...
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2016-12-20ZeitschriftenartikelTransspecies Transmission of Gammaretroviruses and the Origin of the Gibbon Ape Leukaemia Virus (GaLV) and the Koala Retrovirus (KoRV) Transspecies transmission of retroviruses is a frequent event, and the human immunodeficiency virus-1 (HIV-1) is a well-known example. The gibbon ape leukaemia virus (GaLV) and koala retrovirus (KoRV), two gammaretroviruses, ...
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2016-11-30ZeitschriftenartikelAssessing the feasibility of fly based surveillance of wildlife infectious diseases Monitoring wildlife infectious agents requires acquiring samples suitable for analyses, which is often logistically demanding. A possible alternative to invasive or non-invasive sampling of wild-living vertebrates is the ...
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2016-05-23ZeitschriftenartikelPhysical activity surveillance in the European Union: reliability and validity of the European Health Interview Survey-Physical Activity Questionnaire (EHIS-PAQ) Background: The current study examined the reliability and validity of the European Health Interview Survey-Physical Activity Questionnaire (EHIS-PAQ), a novel questionnaire for the surveillance of physical activity ...
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2016-01-21ZeitschriftenartikelGenome Sequences of Murine Pneumotropic Virus (Polyomaviridae) Detected in Wild House Mice (Mus musculus) Using generic PCR, we identified a variant of murine pneumotropic virus (MptV) (family Polyomaviridae) in 3 wild house mice (Mus musculus). The fully amplified and sequenced genomes display considerable differences from ...