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Anzeige der Publikationen 10981-11000 von 12258
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2012-08-22ZeitschriftenartikelInduction of Antibodies Specific for Gp41 of HIV-1 by Gene Gun DNA Vaccination All attempts to induce broadly neutralising antibodies such as mAb 2F5 and mAb 4E10 targeting conserved epitopes in the membrane proximal external region (MPER) of the transmembrane envelope (TM) protein gp41 of HIV-1 ...
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2011-11-09ZeitschriftenartikelRNA interference inhibits replication of tick-borne encephalitis virus in vitro. Each year, up to 10,000 cases of infections with the flavivirus tick-borne encephalitis (TBE) virus that affect the central nervous system are reported in Europe and Asia. Due to the potentially severe adverse effects of ...
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2005-02-01ZeitschriftenartikelHuman immunodeficiency virus, hepatitis C and hepatitis B infections among blood donors in Germany 2000-2002: risk of virus transmission and the impact of nucleic acid amplification testing. Blood and plasma donations in Germany are collected by several institutions, namely the German Red Cross, community and hospital-based blood services, private blood centres, commercial plasma donation sites and transfusion ...
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2005-03-01ZeitschriftenartikelVariante Creutzfeld-Jakob-Erkrankung (vCJK) und Transfusionsmedizin Konsequenzen für die Sicherheit von BlutproduktenIm Dezember 2003 wurde bekannt, dass in Großbritannien ein Patient an der Variante Creutzfeld-Jakob-Erkrankung (vCJK) verstorben war, der 6 1/2 Jahre zuvor ein Erythrozytenkonzentrat von einem Spender erhalten hatte, der ...
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2007-10-05ZeitschriftenartikelInfektionsepidemiologische Daten von Blutspendern 2005 Bericht des Robert Koch-Instituts zu den Meldungen nach § 22 TransfusionsgesetzDie Erhebung infektionsepidemiologischer Daten zur Bestimmung der Prävalenz und Inzidenz von HIV-, Hepatitis-C-Virus-(HCV-), Hepatitis-B-Virus-(HBV-) und Syphilisinfektionen im Blut- und Plasmaspendewesen in Deutschland ...
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2011-07-01ZeitschriftenartikelDer einheitliche Spenderfragebogen Seit Februar 2011 steht ein einheitlicher Blutspenderfragebogen für Blut- und Plasmaspender in Deutschland zur Verfügung. Dieser wurde im Auftrag des Arbeitskreises Blut von einer Expertengruppe entwickelt. Der Fragebogen ...
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2012-09-04ZeitschriftenartikelGerman health interview and examination survey for adults (DEGS) - design, objectives and implementation of the first data collection wave Background: The German Health Interview and Examination Survey for Adults (DEGS) is part of the recently established national health monitoring conducted by the Robert Koch Institute. DEGS combines a nationally ...
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2011-10-15ZeitschriftenartikelEpidemiologie des EHEC O104:H4/HUS-Ausbruchs in Deutschland, Mai bis Juli 2011 Von Mai bis Juli 2011 ereignete sich vor allem in Norddeutschland der bisher größte Ausbruch von Infektionen durch enterohämorrhagische Escherichia coli (EHEC) O104:H4 und von hämolytisch-urämischem Syndrom (HUS) mit ...
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2007-05-25ZeitschriftenartikelFepA- and TonB-dependent bacteriophage H8: receptor binding and genomic sequence. H8 is derived from a collection of Salmonella enterica serotype Enteritidis bacteriophage. Its morphology and genomic structure closely resemble those of bacteriophage T5 in the family Siphoviridae. H8 infected S. enterica ...
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2010-05-14ZeitschriftenartikelPork contaminated with Salmonella enterica serovar 4,[5],12:i:-, an emerging health risk for humans. Salmonella enterica subsp. enterica serovar 4,[5],12:i:- is a monophasic variant of S. enterica serovar Typhimurium (antigenic formula 4,[5],12:i:1,2). Worldwide, especially in several European countries and the United ...
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2009-07-22ZeitschriftenartikelMeasles viruses of genotype H1 evade recognition by vaccine-induced neutralizing antibodies targeting the linear haemagglutinin noose epitope The linear haemagglutinin noose epitope (HNE; aa 379-410) is a protective B-cell epitope and considered to be highly conserved in both the vaccine and the wild-type measles virus (MeV) haemagglutinin (H) proteins. Vaccine ...
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2009-02-25ZeitschriftenartikelCross-talk between type three secretion system and metabolism in Yersinia. Pathogenic yersiniae utilize a type three secretion system (T3SS) to inject Yop proteins into host cells in order to undermine their immune response. YscM1 and YscM2 proteins have been reported to be functionally equivalent ...
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2007-11-01ZeitschriftenartikelPrävention von Übergewicht bei Kindern und Jugendlichen Hintergrund: Übergewicht und Adipositas sind ein wachsendes Gesundheitsproblem, welches heute bei Kindern, Jugendlichen und Erwachsenen endemisch ist. Deshalb ist eine Prävention von Übergewicht dringend notwendig. Die ...
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2011-04-06ZeitschriftenartikelCytomegalovirus e127 protein interacts with the inhibitory CD200 receptor. CD200 is a cell surface glycoprotein that binds an inhibitory receptor (CD200R) on myeloid cells. CD200 orthologues are present in many species of virus, and we show that the rat cytomegalovirus CD200 orthologue (e127) is ...
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2011-06-28ZeitschriftenartikelMolecular in situ topology of Aczonin/Piccolo and associated proteins at the mammalian neurotransmitter release site The protein machinery of neurotransmitter exocytosis requires efficient orchestration in space and time, for speed and precision of neurotransmission and also for synaptic ontogeny and plasticity. However, its spatial ...
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2011-01-19ZeitschriftenartikelrapidSTRIPE H1N1 Test for Detection of the Pandemic Swine Origin Influenza A (H1N1) Virus The rapidSTRIPE H1N1 test, based on a nucleic acid lateral-flow assay, has been developed for diagnosis of a swine-origin influenza A (H1N1) virus. This test is simple and cost-effective and allows specific detection of ...
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2011-01-24ZeitschriftenartikelPrevalence of Chlamydia trachomatis among young German adolescents, 2005–06 Background: Chlamydia trachomatis prevalence among 12–17-year-old adolescents in Germany was determined in the present study. Methods: A random age-stratified sample of 1815 urine specimens of boys and girls was selected ...
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2008-11-05ZeitschriftenartikelAnalysis of influenza B virus NS1 protein trafficking reveals a novel interaction with nuclear speckle domains Many proteins that function in the transcription, maturation, and export of metazoan mRNAs are concentrated in nuclear speckle domains, indicating that the compartment is important for gene expression. Here, we show that ...
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2011-10-07ZeitschriftenartikelFrom types to trees: Reconstructing the spatial spread of Staphylococcus aureus based on DNA variation Tracing the spatial spread of pathogens is a key objective of molecular infectious disease epidemiology. Accordingly, a wide range of genotyping approaches have been used to monitor the dissemination of Staphylococcus ...
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2011-10-19ZeitschriftenartikelGrowth of influenza A virus is not impeded by simultaneous removal of the cholesterol binding and acylation sites in the M2 protein Influenza virus assembly and budding occur in the 'budozone', a coalesced raft domain in the plasma membrane. The viral transmembrane protein M2 is implicated in virus particle scission, the ultimate step in virus budding, ...