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Auflistung nach Autor "Norley, Stephen"
Anzeige der Publikationen 1-10 von 10
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2011-12-05ZeitschriftenartikelCharacterization of a monoclonal anti-capsid antibody that cross-reacts with three major primate lentivirus lineages Sanders-Beer, Brigitte E.; Eschricht, Magdalena; Seifried, Janna; Hirsch, Vanessa M.; Allan, Jonathan S.; Norley, StephenMouse monoclonal antibodies with varying specificities against the Gag capsid of simian and human immunodeficiency virus (SIV/HIV) were generated by immunizing mice with whole inactivated SIVagmTYO-1. Monoclonal antibody ...
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2019-03-29ZeitschriftenartikelCross-Protective Potential and Protection-Relevant Immune Mechanisms of Whole Inactivated Influenza Virus Vaccines Are Determined by Adjuvants and Route of Immunization Bhide, Yoshita; Dong, Wei; Gribonika, Inta; Voshart, Daniëlle; Meijerhof, Tjarko; de Vries-Idema, Jacqueline; Norley, Stephen; Guilfoyle, Kate; Skeldon, Sarah; Engelhardt, Othmar G.; Boon, Louis; Christensen, Dennis; Lycke, Nils; Huckriede, AnkeAdjuvanted whole inactivated virus (WIV) influenza vaccines show promise as broadly protective influenza vaccine candidates. Using WIV as basis we assessed the relative efficacy of different adjuvants by carrying out a ...
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2017-03-01ZeitschriftenartikelEvaluating the immunogenicity and safety of a BiondVax-developed universal influenza vaccine (Multimeric-001) either as a standalone vaccine or as a primer to H5N1 influenza vaccine Phase IIb study protocolDoorn, Eva van; Liu, Heng; Ben-Yedidia, Tamar; Hassin, Shimon; Visontai, Ildiko; Norley, Stephen; Frijlink, Henderik W.; Hak, EelkoIntroduction: Influenza is a major respiratory viral infection of humans with high mortality and morbidity rates and profound economic impact. Although influenza vaccines are generally updated yearly to match the viruses ...
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2017-04-04ZeitschriftenartikelEvaluation of the immunogenicity and safety of different doses and formulations of a broad spectrum influenza vaccine (FLU-v) developed by SEEK: study protocol for a single-center, randomized, double-blind and placebo-controlled clinical phase IIb trial Doorn, Eva van; Pleguezuelos, Olga; Liu, Heng; Fernandez, Ana; Bannister, Robin; Stoloff, Gregory; Oftung, Fredrik; Norley, Stephen; Huckriede, Anke; Frijlink, Henderik W.; Hak, EelkoBackground: Current influenza vaccines, based on antibodies against surface antigens, are unable to provide protection against newly emerging virus strains which differ from the vaccine strains. Therefore the population ...
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2012-12-01ZeitschriftenartikelHER2/neu DNA vaccination by intradermal gene delivery in a mouse tumor model Gene gun is superior to jet injector in inducing CTL responses and protective immunityNguyen-Hoai, Tam; Kobelt, Dennis; Hohn, Oliver; Vu, Minh D.; Schlag, Peter M.; Dörken, Bernd; Norley, Stephen; Lipp, Martin; Walther, Wolfgang; Pezzutto, Antonio; Westermann, JörgDNA vaccines are potential tools for the induction of immune responses against both infectious disease and cancer. The dermal application of DNA vaccines is of particular interest since the epidermal and dermal layers of ...
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2011-03-16ZeitschriftenartikelJoint production of prime/boost pairs of Fowlpox Virus and Modified Vaccinia Ankara recombinants carrying the same transgene Soprana, Elisa; Panigada, Maddalena; Knauf, Mathias; Radaelli, Antonia; Vigevani, Luisa; Palini, Alessio; Villa, Chiara; Malnati, Mauro; Cassina, Giulia; Kurth, Reinhard; Norley, Stephen; Siccardi, Antonio G.Pairs of recombinant MVA (Modified Vaccinia Ankara) and FPV (Fowlpox Virus) expressing the same transgene are reasonable candidates for prime/boost regimens, because cross-reacting immune responses between the two vectors, ...
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2004-03-03ZeitschriftenartikelKonferenz zu Impfstoffentwicklung und innovativen Therapiekonzepten bei HIV/AIDS am Robert Koch-Institut Norley, Stephen
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2017-08-22ZeitschriftenartikelNo significant HTLV seroprevalence in German people who inject drugs Hohn, Oliver; Norley, Stephen; Kücherer, Claudia; Bazarbachi, Ali; Hajj, Hiba El; Marcus, Ulrich; Zimmermann, Ruth; Bannert, NorbertBackground: Although human T-lymphotropic virus (HTLV) is transmitted via the same routes as human immunodeficiency virus (HIV), its worldwide seroprevalence differs drastically because HTLV is transmitted mainly via ...
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2009-06-21ZeitschriftenartikelRole of complement and antibodies in controlling infection with pathogenic simian immunodeficiency virus (SIV) in macaques vaccinated with replication-deficient viral vector Falkensammer, Barbara; Rubner, Barbara; Hiltgartner, Alexander; Wilflingseder, Doris; Stahl-Hennig, Christiane; Kuate, Seraphin; Ueberla, Klaus; Norley, Stephen; Strasak, Alexander; Racz, Paul; Stoiber, HeribertBackground: We investigated the interplay between complement and antibodies upon priming with single-cycle replicating viral vectors (SCIV) encoding SIV antigens combined with Adeno5-SIV or SCIV pseudotyped with murine ...
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2014-05-08ZeitschriftenartikelTimed Action of IL-27 Protects from Immunopathology while Preserving Defense in Influenza Liu, Francesca Diane M.; Kenngott, Elisabeth E.; Schröter, Micha F.; Kühl, Anja; Jennrich, Silke; Watzlawick, Ralf; Hoffmann, Ute; Wolff, Thorsten; Norley, Stephen; Scheffold, Alexander; Stumhofer, Jason S.; Saris, Christiaan J. M.; Schwab, Jan M.; Hunter, Christopher A.; Debes, Gudrun F.; Hamann, AlfInfection with influenza virus can result in massive pulmonary infiltration and potentially fatal immunopathology. Understanding the endogenous mechanisms that control immunopathology could provide a key to novel adjunct ...