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Browsing by Author "Jacob, Daniela"
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2022-07-20ZeitschriftenartikelAdaptation of Brucella melitensis Antimicrobial Susceptibility Testing to the ISO 20776 Standard and Validation of the Method Tscherne, Alina; Mantel, Enrico; Boskani, Talar; Budniak, Sylwia; Elschner, Mandy; Fasanella, Antonio; Feruglio, Siri L.; Galante, Domenico; Giske, Christian G.; Grunow, Roland; Henczko, Judit; Hinz, Christin; Iwaniak, Wojciech; Jacob, Daniela; Kedrak-Jablonska, Agnieszka; Jensen, Veronica K.; Johansen, Tone Bjordal; Kahlmeter, Gunnar; Manzulli, Viviane; Matushek, Erika; Melzer, Falk; Nuncio, Maria S.; Papaparaskevas, Joseph; Pelerito, Ana; Solheim, Margrete; Thomann, Susanne; Tsakris, Athanasios; Wahab, Tara; Weiner, Marcin; Zoeller, Lothar; Zange, Sabine; EMERGE AST Working GroupBrucellosis, mainly caused by Brucella (B.) melitensis, is associated with a risk of chronification and relapses. Antimicrobial susceptibility testing (AST) standards for B. melitensis are not available, and the agent is ...
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2013-03-28ZeitschriftenartikelAnthrax among heroin users in Europe possibly caused by same Bacillus anthracis strain since 2000 Grunow, Roland; Klee, Silke; Beyer, W.; George, Maja; Grunow, D.; Barduhn, Anne; Jacob, Daniela; Elschner, M.; Sandven, P.; Kjerulf, A.; Jensen, J. S.; Cai, Wei; Zimmermann, Ruth; Schaade, LarsInjection anthrax was described first in 2000 in a heroin-injecting drug user in Norway. New anthrax cases among heroin consumers were detected in the United Kingdom (52 cases) and Germany (3 cases) in 2009-10. In June ...
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2014-11-11ZeitschriftenartikelBenefits of a European project on diagnostics of highly pathogenic agents and assessment of potential “dual use” issues Grunow, Roland; Ippolito, G.; Jacob, Daniela; Sauer, Ursula; Rohleder, Anna; Caro, A. Di; Iacovino, R.Quality assurance exercises and networking on the detection of highly infectious pathogens (QUANDHIP) is a joint action initiative set up in 2011 that has successfully unified the primary objectives of the European Network ...
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2003-11-01ZeitschriftenartikelBioterroristisch relevante bakterielle Erreger Epidemiologie, Klinik, DiagnostikKlee, Silke; Jacob, Daniela; Nattermann, Herbert; Appel, BerndNach den bioterroristischen Anschlägen mit Milzbrandbriefen in den USA im Herbst 2001, den Tausenden daraufhin folgenden vermeintlichen Anschlägen auch in Deutschland und den vermuteten Waffenarsenalen in den so genannten ...
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2016-08-04ZeitschriftenartikelBrucellosis in a refugee who migrated from Syria to Germany and lessons learnt, 2016 Grunow, Roland; Jacob, Daniela; Klee, Silke; Schlembach, D.; Jackowski-Dohrmann, S.; Loenning-Baucke, V.; Eberspächer, B.; Swidsinski, S.A teenage woman migrating from Syria arrived in May 2015 in Germany. She gave birth to a healthy child in early 2016, but became febrile shortly after delivery. Blood cultures revealed Brucella melitensis. In retrospect, ...
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2021-04-29ZeitschriftenartikelBurkholderia pseudomallei multi-centre study to establish EUCAST MIC and zone diameter distributions and epidemiological cut-off values Karatuna, Onur; Dance, David Allan Brett; Matuschek, Erika; Åhman, Jenny; Turner, Paul; Hopkins, Jill; Amornchai, Premjit; Wuthiekanun, Vanaporn; Cusack, Tomas Paul; Baird, Robert W.; Hennessy, Jann N.; Norton, Robert Edward L.; Armstrong, Mark Robin; Zange, Sabine; Zoeller, Lothar; Wahab, Tara; Jacob, Daniela; Grunow, Roland; Kahlmeter, GunnarObjectives Melioidosis, caused by Burkholderia pseudomallei, requires intensive antimicrobial treatment. However, standardized antimicrobial susceptibility testing (AST) methodology based on modern principles for ...
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2019-05-06ZeitschriftenartikelClinical characteristics in a sentinel case as well as in a cluster of tularemia patients associated with grape harvest Wetzstein, Nils; Kärcher, Iris; Küpper-Tetzel, Claus P.; Kann, Gerrit; Hogardt, Michael; Jozsa, Katalin; Jacob, Daniela; Grunow, Roland; Just-Nübling, Gudrun; Wolf, TimoBackground Tularemia is caused by Francisella tularensis and can occasionally establish foodborne transmission. Methods Patients were identified by active case detection through contact with the treating physicians and ...
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2018-10-11ZeitschriftenartikelDraft Genome Sequence of Bacillus anthracis Strain Sterne 09RA8929 Busch, Anne; Elschner, Mandy Carolina; Jacob, Daniela; Grunow, Roland; Tomaso, H.A Bacillus anthracis vaccine strain (Sterne), used as an attenuated laboratory comparative strain, was sequenced and analyzed. A comparison to assemblies of B. anthracis strain Sterne (NZ_CP009541 and NZ_CP009540) was ...
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2005-07-28ZeitschriftenartikelEffiziente Abtötung von Milzbrandsporen durch wässrige und alkoholische Peressigsäure–Lösungen Nattermann, Herbert; Becker, Silke; Jacob, Daniela; Klee, Silke; Schwebke, Ingeborg; Appel, BerndMit Suspensions- und Keimträger versuchen wurde die sporizide Wirkung von unterschiedlichen Konzentrationen wässriger und alkoholischer Peressigsäure- (PES-)Lösungen auf Milzbrandsporen untersucht. Während in Suspensionsversuchen ...
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2021-11-15ZeitschriftenartikelEpidemiological investigation of a tularaemia outbreak after a hare hunt in Bavaria, Germany, 2018 Böhm, Stefanie; vom Berge, Katharina; Hierhammer, Daniela; Jacob, Daniela; Grunow, Roland; Riehm, Julia M.; Konrad, Regina; Dauer, Marc; Bouschery, Berit; Hossain, Hamid; Schichtl, Elisabeth; Böhmer, Merle M.In November 2018, a tularaemia outbreak occurred in Bavaria, Germany, among participants of a hare hunt and butchery employees handling the hares. We con-ducted an epidemiological outbreak investigation, including a ...
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2003-07-15DissertationErkennung von Regulationssequenzen für die Transkription in heterologen Systemen Jacob, DanielaMit dieser Arbeit sollte die Spezifität von Promotoren analysiert und ihre Funktionalität über `kingdom´-Grenzen hinaus untersucht werden. Hierfür wurden zwölf pflanzenspezifische Promotoren, welche in der Gentechnik zur ...
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2019-11-06ZeitschriftenartikelGenetic Diversity and Spatial Segregation of Francisella tularensis Subspecies holarctica in Germany Appelt, Sandra; Köppen, Kristin; Radonić, Aleksandar; Drechsel, Oliver; Jacob, Daniela; Grunow, Roland; Heuner, KlausFrancisella tularensis is an intracellular pleomorphic bacterium and the causative agent of tularemia, a zoonotic disease with a wide host range. Among the F. tularensis subspecies, especially F. tularensis subsp. holarctica ...
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2021-10-14ZeitschriftenartikelHeatwave-associated Vibrio infections in Germany, 2018 and 2019 Brehm, Thomas Theo; Berneking, Laura; Martins, Meike Sena; Dupke, Susann; Jacob, Daniela; Drechsel, Oliver; Bohnert, Jürgen; Becker, Karsten; Kramer, Axel; Christner, Martin; Aepfelbacher, Martin; Schmiedel, Stefan; Rohde, Holger; the German Vibrio Study GroupBackground: Vibrio spp. are aquatic bacteria that prefer warm seawater with moderate salinity. In humans, they can cause gastroenteritis, wound infections, and ear infections. During the summers of 2018 and 2019, unprecedented ...
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2016-01-07ZeitschriftenartikelImported cholera with acute renal failure after a short business-trip to the Philippines, Germany, October 2015 Slesak, G.; Fleck, R.; Jacob, Daniela; Grunow, Roland; Schäfer, J.A German businessman developed acute watery diarrhoea after a three-day trip to the Philippines. He was admitted with severe hypotension and acute renal failure, but recovered with rapid rehydration. Vibrio cholerae O1 ...
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2012-12-07ZeitschriftenartikelInjektionsmilzbrand – neu aufgetretene Fälle bei Heroinabhängigen Injection Anthrax—a New Outbreak in Heroin UsersGrunow, Roland; Verbeek, Luzie; Jacob, Daniela; Holzmann, Thomas; Birkenfeld, Gabriele; Wiens, Daniel; Eichel-Streiber, Leonie von; Grass, Gregor; Reischl, UdoHintergrund: Injektionsmilzbrand ist eine seltene Erkrankung bei Heroinkonsumierenden und wird durch Bacillus anthracis verursacht. Im Jahr 2012 sind vier Fälle in Deutschland aufgetreten, wovon ein Fall tödlich verlief, ...
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2019-03-15ZeitschriftenartikelMolecular identification of the source of an uncommon tularaemia outbreak, Germany, autumn 2016 Jacob, Daniela; Köppen, Kristin; Radonić, Aleksandar; Haldemann, Berit; Zanger, Philipp; Heuner, Klaus; Grunow, RolandBackground In 2016, an uncommon outbreak of oropharyngeal tularaemia involving six human cases occurred in Germany, caused by drinking contaminated fresh must after a grape harvest. Aim We describe the details of ...
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2010-04-30ZeitschriftenartikelPentaplexed quantitative real-time PCR assay for the simultaneous detection and quantification of botulinum neurotoxin-producing clostridia in food and clinical samples Kirchner, Sebastian; Krämer, Melanie; Schulze, Martin; Pauly, Diana; Jacob, Daniela; Gessler, Frank; Nitsche, Andreas; Dorner, Brigitte; Dorner, MartinBotulinum neurotoxins are produced by the anaerobic bacterium Clostridium botulinum and are divided into seven distinct serotypes (A to G) known to cause botulism in animals and humans. In this study, a multiplexed ...
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2018-03-22ZeitschriftenartikelPopulation Genomics of Francisella tularensis subsp. holarctica and its Implication on the Eco-Epidemiology of Tularemia in Switzerland Wittwer, Matthias; Altpeter, Ekkehard; Pilo, Paola; Gygli, Sebastian M.; Beuret, Christian; Foucault, Frederic; Ackermann-Gäumann, Rahel; Karrer, Urs; Jacob, Daniela; Grunow, Roland; Schürch, NadiaWhole genome sequencing (WGS) methods provide new possibilities in the field of molecular epidemiology. This is particularly true for monomorphic organisms where the discriminatory power of traditional methods (e.g., ...
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2012-06-29ZeitschriftenartikelRapid and high-throughput detection of highly pathogenic bacteria by Ibis PLEX-ID technology Jacob, Daniela; Sauer, Ursula; Housley, Roberta; Washington, Cicely; Sannes-Lowery, Kristin; Ecker, David J.; Sampath, Rangarajan; Grunow, RolandIn this manuscript, we describe the identification of highly pathogenic bacteria using an assay coupling biothreat group-specific PCR with electrospray ionization mass spectrometry (PCR/ESI-MS) run on an Ibis PLEX-ID ...
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2018-02-16ZeitschriftenartikelTularemia in Germany—A Re-emerging Zoonosis Faber, Mirko; Heuner, Klaus; Jacob, Daniela; Grunow, RolandTularemia, also known as “rabbit fever,” is a zoonosis caused by the facultative intracellular, gram-negative bacterium Francisella tularensis. Infection occurs through contact with infected animals (often hares), arthropod ...