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Browsing by Author "Doellinger, Joerg"
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2018-01-29ZeitschriftenartikelGlobal ubiquitination analysis reveals extensive modification and proteasomal degradation of cowpox virus proteins, but preservation of viral cores Grossegesse, Marica; Doellinger, Joerg; Fritsch, Annemarie; Laue, Michael; Piesker, Janett; Schaade, Lars; Nitsche, AndreasThe emergence of Variola virus-like viruses by natural evolution of zoonotic Orthopoxviruses, like Cowpox virus (CPXV), is a global health threat. The proteasome is essential for poxvirus replication, making the viral ...
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2020-10-22ZeitschriftenartikelPerspective on Proteomics for Virus Detection in Clinical Samples Grossegesse, Marica; Hartkopf, Felix; Nitsche, Andreas; Schaade, Lars; Doellinger, Joerg; Muth, ThiloOne of the most widely used methods to detect an acute viral infection in clinical specimens is diagnostic real-time polymerase chain reaction. However, because of the COVID-19 pandemic, mass-spectrometry-based proteomics ...
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2019-06-08ZeitschriftenartikelPurple: A Computational Workflow for Strategic Selection of Peptides for Viral Diagnostics Using MS-Based Targeted Proteomics Lechner, Johanna; Hartkopf, Felix; Hiort, Pauline; Nitsche, Andreas; Grossegesse, Marica; Doellinger, Joerg; Renard, Bernhard Y.; Muth, ThiloEmerging virus diseases present a global threat to public health. To detect viral pathogens in time-critical scenarios, accurate and fast diagnostic assays are required. Such assays can now be established using mass ...
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2020-09-08ZeitschriftenartikelSilence as a way of niche adaptation: mecC-MRSA with variations in the accessory gene regulator (agr) functionality express kaleidoscopic phenotypes Huber, Charlotte; Stamm, Ivonne; Ziebuhr, Wilma; Marincola, Gabriella; Bischoff, Markus; Strommenger, Birgit; Jaschkowitz, Greta; Marciniak, Tessa; Cuny, Christiane; Witte, Wolfgang; Doellinger, Joerg; Schaudinn, Christoph; Thürmer, Andrea; Epping, Lennard; Semmler, Torsten; Lübke-Becker, Antina; Wieler, Lothar H.; Walther, BirgitFunctionality of the accessory gene regulator (agr) quorum sensing system is an important factor promoting either acute or chronic infections by the notorious opportunistic human and veterinary pathogen Staphylococcus ...