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Browsing by Author "Radonic, Aleksandar"
Now showing items 1-9 of 9
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2016-05-24ZeitschriftenartikelIn vivo evidence for ribavirin-induced mutagenesis of the hepatitis E virus genome Todt, Daniel; Gisa, Anett; Radonic, Aleksandar; Nitsche, Andreas; Behrendt, Patrick; Suneetha, Pothakamuri Venkata; Pischke, Sven; Bremer, Birgit; Brown, Richard J. P.; Manns, Michael P.; Cornberg, Markus; Bock, Thomas; Steinmann, Eike; Wedemeyer, HeinerObjective: Hepatitis E virus (HEV) infection can take chronic courses in immunocompromised patients potentially leading to liver cirrhosis and liver failure. Ribavirin (RBV) is currently the only treatment option for many ...
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2020-03-20ZeitschriftenartikelMicrobiomes in the insectivorous bat species Mops condylurus rapidly converge in captivity Edenborough, Kathryn M.; Mu, Andre; Mühldorfer, Kristin; Lechner, Johanna; Lander, Angelika; Bokelmann, Marcel; Couacy-Hymann, Emmanuel; Radonic, AleksandarBats are well known reservoir hosts for RNA and DNA viruses. The use of captive bats in research has intensified over the past decade as researchers aim to examine the virus-reservoir host interface. In this study, we ...
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2018-10-08ZeitschriftenartikelParasitic Nematodes Exert Antimicrobial Activity and Benefit From Microbiota-Driven Support for Host Immune Regulation Rausch, Sebastian; Midha, Ankur; Kuhring, Matthias; Affinass, Nicole; Radonic, Aleksandar; Kühl, Anja A.; Bleich, André; Renard, Bernhard Y.; Hartmann, SusanneIntestinal parasitic nematodes live in intimate contact with the host microbiota. Changes in the microbiome composition during nematode infection affect immune control of the parasites and shifts in the abundance of bacterial ...
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2021-03-05ZeitschriftenartikelSARS-CoV-2-Varianten: Evolution im Zeitraffer Oh, Djin-Ye; Kröger, Stefan; Wedde, Marianne; Hartkopf, Felix; Budt, Matthias; Seifried, Janna; Radonic, Aleksandar; Belarbi, Essia; Hölzer, Martin; Böttcher, Sindy; Schubert, Grit; Kaiser, Sandra; Sachse, Andreas; Drechsel, Oliver; Grajcar, Romina; Huska, Matthew; Lanxin, Zhan; Domaszewska, Teresa; Zhang, Lanxin; Brinkmann, Annika; Yahosseini, Kyanoush; Grabenhenrich, Linus; Hamouda, Osamah; Dürrwald, Ralf; Haas, Walter; Calvignac-Spencer, Sébastien; Semmler, Torsten; Schaade, Lars; Mielke, Martin; von Kleist, Max; Fuchs, Stephan; Wieler, Lothar H.; Wolff, ThorstenDas Betacoronavirus SARS-CoV-2 gelangte höchstwahrscheinlich als zoonotischer Erreger gegen Ende 2019 in die menschliche Bevölkerung, vermutlich in Form einer einzelnen Transmission (monophyletischer Ursprung) aus einem ...
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2022-06-02ZeitschriftenartikelSynopse virologischer Analysen im Nationalen Referenzzentrum für Influenzaviren während der COVID-19-Pandemie Dürrwald, Ralf; Wedde, Marianne; Duwe, Susanne; Biere, Barbara; Reiche, Janine; Köndgen, Sophie; Ramos Calderón, Julia Patricia; Budt, Matthias; Drechsel, Oliver; Fuchs, Stephan; Haldemann, Berit; Hartkopf, Felix; Hölzer, Martin; Huska, Matthew; Kaiser, Sandra; Keeren, Kathrin; Kröger, Stefan; Paraskevopoulou, Sofia; Radonic, Aleksandar; Reinhardt, Bernd; Semmler, Torsten; Thürmer, Andrea; Trappe, Kathrin; Winter, Katja; Mielke, Martin; Buda, Silke; Oh, Djin-Ye; Wolff, ThorstenDas Nationale Referenzzentrum für Influenzaviren gewinnt durch die fortlaufende Untersuchung von Proben aus den Sentinelpraxen der Arbeitsgemeinschaft Influenza einen umfassenden Überblick über die zirkulierenden ...
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2023-06-12ZeitschriftenartikelT-Cell-Dominated Immune Response Resolves Protracted SARS-CoV-2 Infection in the Absence of Neutralizing Antibodies in an Immunocompromised Individual Bunse, Till; Koerber, Nina; Wintersteller, Hannah; Schneider, Jochen; Graf, Alexander; Radonic, Aleksandar; Thuermer, Andrea; von Kleist, Max; Blum, Helmut; Spinner, Christoph D.; Bauer, Tanja; Knolle, Percy A.; Protzer, Ulrike; Schulte, Eva C.Immunocompromised individuals are at higher risk of developing protracted and severe COVID-19, and understanding individual disease courses and SARS-CoV-2 immune responses in these individuals is of the utmost importance. ...
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2024-05-12ZeitschriftenartikelThe gut microbiome, resistome, and mycobiome in preterm newborn infants and mouse pups: lack of lasting effects by antimicrobial therapy or probiotic prophylaxis Yuu, Elizabeth Y.; Bührer, Christoph; Eckmanns, Tim; Fulde, Marcus; Herz, Michaela; Kurzai, Oliver; Lindstedt, Christin; Panagiotou, Gianni; Piro, Vitor C.; Radonic, Aleksandar; Renard, Bernhard Y.; Reuss, Annicka; Leal Siliceo, Sara; Thielemann, Nadja; Thürmer, Andrea; van Vorst, Kira; Wieler, Lothar H.; Haller, SebastianBackground: Enhancing our understanding of the underlying influences of medical interventions on the microbiome, resistome and mycobiome of preterm born infants holds significant potential for advancing infection ...
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2022-07-08ZeitschriftenartikelTransmission of SARS-CoV-2 among children and staff in German daycare centres Loss, Julika; Wurm, Juliane; Varnaccia, Gianni; Schienkiewitz, Anja; Iwanowski, Helena; Loer, Anne-Kathrin Mareike; Allen, Jennifer; Wess, Barbara; Schaffrath Rosario, Angelika; Damerow, Stefan; Kuttig, Tim; Perlitz, Hanna; Hornbacher, Anselm; Finkel, Bianca; Krause, Carolin; Wormsbächer, Jan; Sandoni, Anna; Kubisch, Ulrike; Eggers, Kiara; Nitsche, Andreas; Radonic, Aleksandar; Trappe, Kathrin; Drechsel, Oliver; Klaper, Kathleen; Franke, Andrea; Hüther, Antje; Buchholz, Udo; Haas, Walter; Wieler, Lothar H.; Jordan, SusanneIn daycare centres, the close contact of children with other children and employees favours the transmission of infections. The majority of children <6 years attend daycare programmes in Germany, but the role of daycare ...
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2024-03-08ZeitschriftenartikelViral genome sequencing to decipher in-hospital SARS-CoV-2 transmission events Esser, Elisabeth; Schulte, Eva C.; Graf, Alexander; Karollus, Alexander; Smith, Nicholas H.; Michler, Thomas; Dvoretskii, Stefan; Angelov, Angel; Sonnabend, Michael; Peter, Silke; Engesser, Christina; Radonic, Aleksandar; Thürmer, Andrea; von Kleist, Max; Gebhardt, Friedemann; Prazeres da Costa, Clarissa; Busch, Dirk H.; Muenchhoff, Maximilian; Blum, Helmut; Keppler, Oliver T.; Gagneur, Julien; Protzer, UlrikeThe SARS-CoV-2 pandemic has highlighted the need to better define in-hospital transmissions, a need that extends to all other common infectious diseases encountered in clinical settings. To evaluate how whole viral genome ...