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Auflistung nach Autor "Kücherer, Claudia"
Anzeige der Publikationen 1-20 von 37
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2014-08-14ZeitschriftenartikelA multicentre sero-behavioural survey for hepatitis B and C, HIV and HTLV among people who inject drugs in Germany using respondent driven sampling Zimmermann, Ruth; Marcus, Ulrich; Schäffer, Dirk; Leicht, Astrid; Wenz, Benjamin; Nielsen, Stine; Santos-Hövener, Claudia; Ross, Stefan; Stambouli, Oumaima; Ratsch, Boris A.; Bannert, Norbert; Bock, Thomas; Kücherer, Claudia; Hamouda, OsamahBackground: People who inject drugs are at high risk for hepatitis B, hepatitis C and HIV. HTLV was reported by neighboring countries to be prevalent in this population, but the situation for Germany is unclear. To ...
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2014-11-02ZeitschriftenartikelAnalysis of transmitted drug resistance and HIV-1 subtypes using dried serum spots of recently HIV-infected individuals in 2013 in Germany Hauser, Andrea; Hofmann, Alexandra; Santos-Hoevener, Claudia; Zimmermann, Ruth; Hamouda, Osamah; Bannert, Norbert; Kücherer, Claudia
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2008-07-23ZeitschriftenartikelCCR5Delta32 genotypes in a German HIV-1 seroconverter cohort and report of HIV-1 infection in a CCR5Delta32 homozygous individual Oh, Djin-Ye; Jessen, Heiko; Kücherer, Claudia; Neumann, Konrad; Oh, Nari; Poggensee, Gabriele; Bartmeyer, Barbara; Jessen, Arne; Pruss, Axel; Schumann, Ralf R.; Hamouda, OsamahBackground: Homozygosity (Δ32/Δ32) for the 32 bp deletion in the chemokine receptor 5 (CCR5) gene is associated with strong resistance against HIV infection. Heterozygosity is associated with protection of HIV-1 disease ...
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2014-11-02ZeitschriftenartikelCharacterization of natural polymorphic sites of the HIV-1 integrase before the introduction of HIV-1 integrase inhibitors in Germany Meixenberger, Karolin; Yousef, Kaveh Pouran; Somogyi, Sybille; Fiedler, Stefan; Bartmeyer, Barbara; Kleist, Max von; Kücherer, Claudia
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2015-10-15ZeitschriftenartikelComparison of 454 Ultra-Deep Sequencing and Allele-Specific Real-Time PCR with Regard to the Detection of Emerging Drug-Resistant Minor HIV-1 Variants after Antiretroviral Prophylaxis for Vertical Transmission Hauser, Andrea; Kücherer, Claudia; Kunz, Andrea; Dabrowski, Piotr Wojtek; Radonić, Aleksandar; Nitsche, Andreas; Theuring, Stefanie; Bannert, Norbert; Sewangi, Julius; Mbezi, Paulina; Dugange, Festo; Harms, Gundel; Meixenberger, KarolinBackground: Pregnant HIV-infected women were screened for the development of HIV-1 drug resistance after implementation of a triple-antiretroviral transmission prophylaxis as recommended by the WHO in 2006. The study ...
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2016-09-01ZeitschriftenartikelConcordance between self-reported and measured HIV and hepatitis C virus infection status among people who inject drugs in Germany Nielsen, Stine; Gassowski, Martyna; Wenz, Benjamin; Bannert, Norbert; Bock, Thomas; Kücherer, Claudia; Ross, Stefan; Bremer, Viviane; Marcus, Ulrich; Zimmermann, RuthBackground: People who inject drugs (PWID) are disproportionately affected by both HIV and hepatitis C infection (HCV). Awareness of infection status is essential to ensure linkage to appropriate healthcare for those ...
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2014-05-14ZeitschriftenartikelConversation about Serostatus decreases risk of acquiring HIV: results from a case control study comparing MSM with recent HIV infection and HIV negative controls Santos-Hövener, Claudia; Zimmermann, Ruth; Kücherer, Claudia; Bätzing-Feigenbaum, Jörg; Wildner, Stephan; Hamouda, Osamah; Marcus, UlrichBackground: Data on knowledge, attitudes, behaviour and practices (KABP) of persons with recent HIV infection compared to controls with negative HIV test result provide information on current risk patterns and can help ...
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2008-09-04ZeitschriftenartikelCountry-wide HIV incidence study complementing HIV surveillance in Germany Bätzing-Feigenbaum, Jörg; Loschen, Stephan; Gohlke-Micknis, Silvia; Zimmermann, Ruth; Herrmann, Antoinette; Wambo, G. O. Kamga; Kücherer, Claudia; Hamouda, OsamahSerological methods exist that allow differentiating between recent and long-standing infections in persons infected with HIV. During a pilot study in Berlin between 2005 and 2007 methodologies have been evaluated. In a ...
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2011-05-31ZeitschriftenartikelEmergence and Persistence of Minor Drug-Resistant HIV-1 Variants in Ugandan Women after Nevirapine Single-Dose Prophylaxis. Hauser, Andrea; Mugenyi, Kizito; Kabasinguzi, Rose; Kücherer, Claudia; Harms, Gundel; Kunz, AndreaBackground: Nevirapine (NVP) single-dose is still a widely used antiretroviral prophylaxis for the prevention of vertical HIV-1 transmission in resource-limited settings. However, the main disadvantage of the Non-nucleoside ...
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2012-02-23ZeitschriftenartikelEmergence of Minor Drug-Resistant HIV-1 Variants after Triple Antiretroviral Prophylaxis for Prevention of Vertical HIV-1 Transmission Hauser, Andrea; Sewangi, Julius; Mbezi, Paulina; Dugange, Festo; Lau, Inga; Ziske, Judith; Theuring, Stefanie; Kücherer, Claudia; Harms, Gundel; Kunz, AndreaBackground: WHO-guidelines for prevention of mother-to-child transmission of HIV-1 in resource-limited settings recommend complex maternal antiretroviral prophylaxis comprising antenatal zidovudine (AZT), nevirapine ...
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2014-08-22ZeitschriftenartikelEstimating Trends in the Proportion of Transmitted and Acquired HIV Drug Resistance in a Long Term Observational Cohort in Germany Schmidt, Daniel; Kollan, Christian; Fätkenheuer, Gerd; Schülter, Eugen; Stellbrink, Hans-Jürgen; Noah, Christian; Jensen, Björn-Erik Ole; Stoll, Matthias; Bogner, Johannes R.; Eberle, Josef; Meixenberger, Karolin; Kücherer, Claudia; Hamouda, Osamah; Bartmeyer, BarbaraObjective: We assessed trends in the proportion of transmitted (TDR) and acquired (ADR) HIV drug resistance and associated mutations between 2001 and 2011 in the German ClinSurv-HIV Drug Resistance Study. Method: ...
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2014-05-01ZeitschriftenartikelFirst Line Treatment Response in Patients with Transmitted HIV Drug Resistance and Well Defined Time Point of HIV Infection: Updated Results from the German HIV-1 Seroconverter Study Knyphausen, Fabia zu; Scheufele, Ramona; Kücherer, Claudia; Jansen, Klaus; Somogyi, Sybille; Dupke, Stephan; Jessen, Heiko; Schürmann, Dirk; Hamouda, Osamah; Meixenberger, Karolin; Bartmeyer, BarbaraBackground: Transmission of drug-resistant HIV-1 (TDR) can impair the virologic response to antiretroviral combination therapy. Aim of the study was to assess the impact of TDR on treatment success of resistance test-guided ...
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2015-11-10ZeitschriftenartikelHigh Prevalence and High Incidence of Coinfection with Hepatitis B, Hepatitis C, and Syphilis and Low Rate of Effective Vaccination against Hepatitis B in HIV-Positive Men Who Have Sex with Men with Known Date of HIV Seroconversion in Germany Jansen, Klaus; Thamm, Michael; Bock, Thomas; Scheufele, Ramona; Kücherer, Claudia; Muenstermann, Dieter; Hagedorn, Hans-Jochen; Jessen, Heiko; Dupke, Stephan; Hamouda, Osamah; Gunsenheimer-Bartmeyer, Barbara; Meixenberger, KarolinObjectives: Men who have sex with men (MSM) are at higher risk for coinfection with hepatitis B virus (HBV), hepatitis C virus (HCV), and syphilis than the general population. HIV infection and these coinfections ...
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2016-09-05ZeitschriftenartikelHigh variability of HIV and HCV seroprevalence and risk behaviours among people who inject drugs: results from a cross-sectional study using respondent-driven sampling in eight German cities (2011–14) Wenz, Benjamin; Nielsen, Stine; Gassowski, Martyna; Santos-Hövener, Claudia; Cai, Wei; Ross, Stefan; Bock, Thomas; Ratsch, Boris-Alexander; Kücherer, Claudia; Bannert, Norbert; Bremer, Viviane; Hamouda, Osamah; Marcus, Ulrich; Zimmermann, RuthBackground: People who inject drugs (PWID) are at increased risk of acquiring and transmitting HIV and Hepatitis C (HCV) due to sharing injection paraphernalia and unprotected sex. To generate seroprevalence data on HIV ...
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2015-08-31ZeitschriftenartikelHIV Testing and Diagnosis Rates in Kiev, Ukraine: April 2013 - March 2014 Kücherer, Claudia; Simmons, Ruth; Bartmeyer, Barbara; Malyuta, Ruslan; Chentsova, Nelli; Medoeva, Antonia; Kruglov, Yuri; Yurchenko, Alexander; Copas, Andrew; Porter, Kholoud; Hamouda, OsamahObjective: Data from Ukraine on risk factors for HIV acquisition are limited. We describe the characteristics of individuals testing for HIV in the main testing centres of the Ukrainian capital Kiev, including HIV risk ...
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2013-01-14ZeitschriftenartikelHIV-1 subtype distribution and its demographic determinants in newly diagnosed patients in Europe suggest highly compartmentalized epidemics Abecasis, Ana B.; Wensing, Annemarie M. J.; Paraskevis, Dimitris; Vercauteren, Jurgen; Theys, Kristof; Vijver, David A. M. C. van de; Albert, Jan; Asjö, Birgitta; Balotta, Claudia; Beshkov, Danail; Camacho, Ricardo J.; Clotet, Bonaventura; Gascun, Cillian De; Griskevicius, Algis; Grossman, Zehava; Hamouda, Osamah; Horban, Andrzej; Kolupajeva, Tatjana; Korn, Klaus; Kostrikis, Leon G.; Kücherer, ClaudiaBackground: Understanding HIV-1 subtype distribution and epidemiology can assist preventive measures and clinical decisions. Sequence variation may affect antiviral drug resistance development, disease progression, ...
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2014-06-03ZeitschriftenartikelImproved Testing of Recent HIV-1 Infections with the BioRad Avidity Assay Compared to the Limiting Antigen Avidity Assay and BED Capture Enzyme Immunoassay: Evaluation Using Reference Sample Panels from the German Seroconverter Cohort Hauser, Andrea; Santos-Hövener, Claudia; Meixenberger, Karolin; Zimmermann, Ruth; Somogyi, Sybille; Fiedler, Stefan; Hofmann, Alexandra; Bartmeyer, Barbara; Jansen, Klaus; Hamouda, Osamah; Bannert, Norbert; Kücherer, ClaudiaBackground: The variety and limitations of current laboratory methods for estimating HIV-incidence has driven attempts to improve and standardize the performance of serological ‘Tests for Recent HIV-Infections’ (TRI). ...
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2014-07-21ZeitschriftenartikelIncrease in transmitted resistance to non-nucleoside reverse transcriptase inhibitors among newly diagnosed HIV-1 infections in Europe Frentz, Dineke; Vijver, David A. M. C. van de; Abecasis, Ana B.; Albert, Jan; Hamouda, Osamah; Jørgensen, Louise B.; Kücherer, Claudia; Struck, Daniel; Schmit, Jean-Claude; Vercauteren, Jurgen; Åsjö, Birgitta; Balotta, Claudia; Beshkov, Danail; Camacho, Ricardo J.; Clotet, Bonaventura; Coughlan, Suzie; Griskevicius, Algirdas; Grossman, Zehava; Horban, Andrzej; Kolupajeva, Tatjana; Korn, Klaus; Kostrikis, Leondios G.; Liitsola, Kirsi; Linka, Marek; Nielsen, ClausBackground: One out of ten newly diagnosed patients in Europe was infected with a virus carrying a drug resistant mutation. We analysed the patterns over time for transmitted drug resistance mutations (TDRM) using data ...
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2013-04-03ZeitschriftenartikelLimited cross-border infections in patients newly diagnosed with HIV in Europe Frentz, Dineke; Wensing, Annemarie M. J.; Albert, Jan; Paraskevis, Dimitrios; Abecasis, Ana B.; Hamouda, Osamah; Jørgensen, Louise B.; Kücherer, Claudia; Struck, Daniel; Schmit, Jean-Claude; Åsjö, Birgitta; Balotta, Claudia; Beshkov, Danail; Camacho, Ricardo J.; Clotet, Bonaventura; Coughlan, Suzie; Wit, Stéphane De; Griskevicius, Algirdas; Grossman, Zehava; Horban, Andrzej; Kolupajeva, Tatjana; Korn, Klaus; Kostrikis, Leondios G.; Liitsola, Kirsi; Linka, MarekBackground: International travel plays a role in the spread of HIV-1 across Europe. It is, however, not known whether international travel is more important for spread of the epidemic as compared to endogenous infections ...
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2010-11-29ZeitschriftenartikelMinor drug-resistant HIV type-1 variants in breast milk and plasma of HIV type-1-infected Ugandan women after nevirapine single-dose prophylaxis Pilger, Daniel; Hauser, Andrea; Kücherer, Claudia; Mugenyi, Kizito; Kabasinguzi, Rose; Somogyi, Sybille; Harms, Gundel; Kunz, AndreaBackground: Nevirapine single-dose (NVP-SD) reduces mother-to-child transmission of HIV type-1 (HIV-1), but frequently induces resistance mutations in the HIV-1 genome. Little is known about drug-resistant HIV-1 variants ...