- edoc-Server Home
- Browsing by Author
Browsing by Author "Kücherer, Claudia"
Now showing items 21-37 of 37
-
2017-11-14ZeitschriftenartikelMolecular evolution of HIV-1 integrase during the 20 years prior to the first approval of integrase inhibitors Meixenberger, Karolin; Yousef, Kaveh Pouran; Smith, Maureen Rebecca; Somogyi, Sybille; Fiedler, Stefan; Bartmeyer, Barbara; Hamouda, Osamah; Bannert, Norbert; Kleist, Max von; Kücherer, ClaudiaBackground: Detailed knowledge of the evolutionary potential of polymorphic sites in a viral protein is important for understanding the development of drug resistance in the presence of an inhibitor. We therefore set ...
-
2015-06-27Berichte und sonstige TexteNachweis einer Infektion mit Humanem Immundefizienzvirus (HIV): Serologisches Screening mit nachfolgender Bestätigungsdiagnostik durch Antikörper-basierte Testsysteme und/oder durch HIV-Nukleinsäure-Nachweis Stellungnahme der Gemeinsamen Diagnostikkommission der Deutschen Vereinigung zur Bekämpfung von Viruskrankheiten e. V. (DVV e. V.) und der Gesellschaft für Virologie e. V. (GfV e. V.)Rabenau, Holger F.; Bannert, Norbert; Berger, Annemarie; Donoso Mantke, Oliver; Eberle, Josef; Enders, Martin; Fickenscher, Helmut; Grunert, Hans-Peter; Gürtler, Lutz; Heim, Albert; Huzly, Daniela; Kaiser, Rolf; Korn, Klaus; Nick, Sigrid; Kücherer, Claudia; Nübling, Micha; Obermeier, Martin; Panning, Marcus; Zeichhardt, Heinz; In Kooperation mit: Deutsche AIDS Gesellschaft e. V. (DAIG e. V.), Deutsche Arbeitsgemeinschaft niedergelassener Ärzte in der Versorgung HIV-Infizierter e. V. (DAGNÄ e. V.), Berufsverband der Ärzte für Mikrobiologie, Virologie und Infektionsepidemiologie e. V. (BÄMI e. V.)
-
2017-01-12ZeitschriftenartikelNational molecular surveillance of recently acquired HIV infections in Germany, 2013 to 2014 Hauser, Andrea; Hofmann, Alexandra; Hanke, Kirsten; Bremer, Viviane; Bartmeyer, Barbara; Kücherer, Claudia; Bannert, NorbertTo enable an up-to-date molecular analysis of human immunodeficiency virus (HIV) genotypes circulating in Germany we have established a surveillance system based on recently acquired HIV infections. New HIV infections are ...
-
2011-02-01ZeitschriftenartikelNo evidence for transmission of SIVwrc from western red colobus monkeys (piliocolobus badius badius) to wild west african chimpanzees (pan troglodytes verus) despite high exposure through hunting Leendertz, Siv Aina J.; Locatelli, Sabrina; Boesch, Christophe; Kücherer, Claudia; Formenty, Pierre; Liegeois, Florian; Ayouba, Ahidjo; Peeters, Martine; Leendertz, FabianBackground: Simian Immunodeficiency Viruses (SIVs) are the precursors of Human Immunodeficiency Viruses (HIVs) which have lead to the worldwide HIV/AIDS pandemic. By studying SIVs in wild primates we can better understand ...
-
2017-08-22ZeitschriftenartikelNo significant HTLV seroprevalence in German people who inject drugs Hohn, Oliver; Norley, Stephen; Kücherer, Claudia; Bazarbachi, Ali; Hajj, Hiba El; Marcus, Ulrich; Zimmermann, Ruth; Bannert, NorbertBackground: Although human T-lymphotropic virus (HTLV) is transmitted via the same routes as human immunodeficiency virus (HIV), its worldwide seroprevalence differs drastically because HTLV is transmitted mainly via ...
-
2014-04-10ZeitschriftenartikelPatterns of Transmitted HIV Drug Resistance in Europe Vary by Risk Group Frentz, Dineke; Vijver, David van de; Abecasis, Ana B.; Albert, Jan; Hamouda, Osamah; Jørgensen, Louise; Kücherer, Claudia; Struck, Daniel; Schmit, Jean-Claude; Vercauteren, Jurgen; Åsjö, Birgitta; Balotta, Claudia; Bergin, Colm; Beshkov, Danail; Camacho, Ricardo; Clotet, Bonaventura; Griskevicius, Algirdas; Grossman, Zehava; Horban, Andrzej; Kolupajeva, Tatjana; Korn, Klaus; Kostrikis, Leondios; Liitsola, Kirsi; Nielsen, Claus; Otelea, DanBackground: In Europe, a continuous programme (SPREAD) has been in place for ten years to study transmission of drug resistant HIV. We analysed time trends of transmitted drug resistance mutations (TDRM) in relation to ...
-
2009-10-02ZeitschriftenartikelPiloting second generation HIV surveillance in Berlin, Germany, 2005 - 2007 Risk profile of recently acquired HIV infections in MSMBätzing-Feigenbaum, Jörg; Loschen, Stephan; Gohlke-Micknis, Silvia; Zimmermann, Ruth; Kücherer, Claudia; Hamouda, OsamahMen having sex with men (MSM) are by far the transmission-risk-category most affected by HIV in Berlin and were investigated in this pilot-study with the aim to identify detailed risk- and prevention-behaviours in recently ...
-
2019-01-16ZeitschriftenartikelPrevalence and persistence of transmitted drug resistance mutations in the German HIV-1 Seroconverter Study Cohort Machnowska, Patrycja; Meixenberger, Karolin; Schmidt, Daniel; Jessen, Heiko; Hillenbrand, Heribert; Gunsenheimer-Bartmeyer, Barbara; Hamouda, Osamah; Kücherer, Claudia; Bannert, NorbertThe prevalence of transmitted drug resistance (TDR) in antiretroviral therapy (ART)-naïve individuals remains stable in most developed countries despite a decrease in the prevalence of acquired drug resistance. This suggests ...
-
2010-10-07ZeitschriftenartikelPrevalence of Transmitted Drug Resistance and Impact of Transmitted Resistance on Treatment Success in the German HIV-1 Seroconverter Cohort Bartmeyer, Barbara; Kücherer, Claudia; Houareau, Claudia; Werning, Johanna; Keeren, Katrin; Somogyi, Sybille; Kollan, Christian; Jessen, Heiko; Dupke, Stephan; Hamouda, OsamahBackground: The aim of this study is to analyse the prevalence of transmitted drug resistance, TDR, and the impact of TDR on treatment success in the German HIV-1 Seroconverter Cohort. Methods: Genotypic resistance ...
-
2010-04-01ZeitschriftenartikelRetroviruses in Wild-Born Semi-Captive East African Sanctuary Chimpanzees (Pan troglodytes schweinfurthii) Mugisha, Lawrence; Kücherer, Claudia; Ellerbrok, Heinz; Junglen, Sandra; Opuda-Asibo, John; Joseph, Olobo O.; Pauli, Georg; Leendertz, FabianInformation on retroviruses infections in great apes is scarce, especially for apes kept in sanctuaries throughout Africa. To investigate the prevalence of retroviruses and possible transmission of different retroviruses ...
-
2017-07-11ZeitschriftenartikelSurveillance of recent HIV infections among newly diagnosed HIV cases in Germany between 2008 and 2014 Hofmann, Alexandra; Hauser, Andrea; Zimmermann, Ruth; Santos-Hövener, Claudia; Bätzing-Feigenbaum, Jörg; Wildner, Stephan; Kücherer, Claudia; Bannert, Norbert; Hamouda, Osamah; Bremer, Viviane; Bartmeyer, BarbaraBackground: The HIV surveillance system in Germany is based on mandatory, anonymous notification of newly diagnosed HIV cases by laboratories. Because the time between HIV infection and the diagnosis of HIV varies widely ...
-
2010-02-18ZeitschriftenartikelTime trends of syphilis and HSV-2 co-infection among men who have sex with men in the German HIV-1 seroconverter cohort from 1996–2007 Spielmann, Nadine; Münstermann, Dieter; Hagedorn, Hans-Jochen; Heiden, Matthias an der; Houareau, Claudia; Gunsenheimer-Bartmeyer, Barbara; Kücherer, Claudia; Keeren, Katrin; Hamouda, Osamah; Marcus, UlrichObjectives: Numbers of newly diagnosed HIV infections among men who have sex with men (MSM) in Germany increased after the year 2000. We sought to explore trends in STI co-infections around the time of HIV seroconversion ...
-
2010-10-01ZeitschriftenartikelTime trends of syphilis and HSV-2 co-infection among men who have sex with men in the German HIV-1 seroconverter cohort from 1996–2007 Spielmann, Nadine; Münstermann, Dieter; Hagedorn, Hans-Jochen; Heiden, Matthias an der; Houareau, Claudia; Gunsenheimer-Bartmeyer, Barbara; Kücherer, Claudia; Keeren, Katrin; Hamouda, Osamah; Marcus, UlrichObjectives: Numbers of newly diagnosed HIV infections among men who have sex with men (MSM) in Germany increased after the year 2000. We sought to explore trends in STI co-infections around the time of HIV seroconversion ...
-
2009-11-15ZeitschriftenartikelTransmission of Drug‐Resistant HIV‐1 is Stabilizing in Europe Vercauteren, Jurgen; Wensing, Annemarie M. J.; Vijver, David A. M. C. van de; Albert, Jan; Balotta, Claudia; Hamouda, Osamah; Kücherer, Claudia; Struck, Daniel; Schmit, Jean-Claude; Asjo, Birgitta; Bruckova, Marie; Camacho, Ricardo; Clotet, Bonaventura; Coughlan, Suzie; Grossman, Zehava; Horban, Andrzej; Korn, Klaus; Kostrikis, Leondios; Nielsen, Claus; Paraskevis, Dimitrios; Poljak, Mario; Puchhammer-Stöckl, Elisabeth; Riva, Chiara; Ruiz, Lidia; Salminen, MikaThe SPREAD Programme investigated prospectively the time trend from September 2002 through December 2005 of transmitted drug resistance (TDR) among 2793 patients in 20 European countries and in Israel with newly diagnosed ...
-
2012-10-03ZeitschriftenartikelTreatment-associated polymorphisms in protease are significantly associated with higher viral load and lower CD4 count in newly diagnosed drug-naive HIV-1 infected patients Theys, Kristof; Deforche, Koen; Vercauteren, Jurgen; Libin, Pieter; Vijver, David A. M. C. van de; Albert, Jan; Åsjö, Birgitta; Balotta, Claudia; Bruckova, Marie; Camacho, Ricardo J.; Clotet, Bonaventura; Coughlan, Suzie; Grossman, Zehava; Hamouda, Osamah; Horban, Andrzei; Korn, Klaus; Kostrikis, Leondios G.; Kücherer, Claudia; Nielsen, Claus; Paraskevis, Dimitrios; Poljak, Mario; Puchhammer-Stockl, Elisabeth; Riva, Chiara; Ruiz, Lidia; Liitsola, KirsiBackground: The effect of drug resistance transmission on disease progression in the newly infected patient is not well understood. Major drug resistance mutations severely impair viral fitness in a drug free environment, ...
-
2014-07-08ZeitschriftenartikelTrends and Predictors of Transmitted Drug Resistance (TDR) and Clusters with TDR in a Local Belgian HIV-1 Epidemic Pineda-Peña, Andrea-Clemencia; Schrooten, Yoeri; Vinken, Lore; Ferreira, Fossie; Li, Guangdi; Trovão, Nídia Sequeira; Khouri, Ricardo; Derdelinckx, Inge; Munter, Paul De; Kücherer, Claudia; Kostrikis, Leondios G.; Nielsen, Claus; Littsola, Kirsi; Wensing, Annemarie; Stanojevic, Maja; Paredes, Roger; Balotta, Claudia; Albert, Jan; Boucher, Charles; Gomez-Lopez, Arley; Wijngaerden, Eric van; Ranst, Marc van; Vercauteren, Jurgen; Vandamme, Anne-Mieke; Laethem, Kristel vanWe aimed to study epidemic trends and predictors for transmitted drug resistance (TDR) in our region, its clinical impact and its association with transmission clusters. We included 778 patients from the AIDS Reference ...
-
2013-07-30ZeitschriftenartikelVirologic and Immunologic Response to cART by HIV-1 Subtype in the CASCADE Collaboration Touloumi, Giota; Pantazis, Nikos; Chaix, Marie-Laure; Bucher, Heiner C.; Zangerle, Robert; Kran, Anne-Marte Bakken; Thiebaut, Rodolphe; Masquelier, Bernard; Kücherer, Claudia; Monforte, Antonella d'Arminio; Meyer, Laurence; Porter, KholoudBackground: We aimed to compare rates of virologic response and CD4 changes after combination antiretroviral (cART) initiation in individuals infected with B and specific non-B HIV subtypes. Methods: Using CASCADE ...