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Auflistung nach Autor "Bannert, Norbert"
Anzeige der Publikationen 21-40 von 59
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2011-10-19ZeitschriftenartikelGrowth of influenza A virus is not impeded by simultaneous removal of the cholesterol binding and acylation sites in the M2 protein Thaa, Bastian; Tielesch, Claudia; Möller, Lars; Schmitt, Armin O.; Wolff, Thorsten; Bannert, Norbert; Herrmann, Andreas; Veit, MichaelInfluenza virus assembly and budding occur in the 'budozone', a coalesced raft domain in the plasma membrane. The viral transmembrane protein M2 is implicated in virus particle scission, the ultimate step in virus budding, ...
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2013-09-20ZeitschriftenartikelHERV-K(HML-2), the best preserved family of HERVs: endogenization, expression, and implications in health and disease Hohn, Oliver; Hanke, Kirsten; Bannert, NorbertRetroviruses that have the ability to infect germ line cells can become an integral and inherited part of the host genome. About 8% of the human chromosomal DNA consists of sequences derived from infections by retroviruses ...
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2018-02-13ZeitschriftenartikelHERVs New Role in Cancer: From Accused Perpetrators to Cheerful Protectors Bannert, Norbert; Hofmann, Henning; Block, Adriana; Hohn, OliverInitial indications that retroviruses are connected to neoplastic transformation were seen more than a century ago. This concept has also been tested for endogenized retroviruses (ERVs) that are abundantly expressed in ...
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2016-09-05ZeitschriftenartikelHigh variability of HIV and HCV seroprevalence and risk behaviours among people who inject drugs: results from a cross-sectional study using respondent-driven sampling in eight German cities (2011–14) Wenz, Benjamin; Nielsen, Stine; Gassowski, Martyna; Santos-Hövener, Claudia; Cai, Wei; Ross, Stefan; Bock, Thomas; Ratsch, Boris-Alexander; Kücherer, Claudia; Bannert, Norbert; Bremer, Viviane; Hamouda, Osamah; Marcus, Ulrich; Zimmermann, RuthBackground: People who inject drugs (PWID) are at increased risk of acquiring and transmitting HIV and Hepatitis C (HCV) due to sharing injection paraphernalia and unprotected sex. To generate seroprevalence data on HIV ...
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2011-02-16ZeitschriftenartikelHighly conserved serine residue 40 in HIV-1 p6 regulates capsid processing and virus core assembly Votteler, Jörg; Neumann, Liane; Hahn, Sabine; Hahn, Friedrich; Rauch, Pia; Schmidt, Kerstin; Studtrucker, Nicole; Solbak, Sara MØ; Fossen, Torgils; Henklein, Peter; Ott, David E.; Holland, Gudrun; Bannert, Norbert; Schubert, UlrichBackground: The HIV-1 p6 Gag protein regulates the final abscission step of nascent virions from the cell membrane by the action of two late assembly (L-) domains. Although p6 is located within one of the most polymorphic ...
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2019-01-08ZeitschriftenartikelHistory of detention and the risk of hepatitis C among people who inject drugs in Germany Gassowski, Martyna; Nielsen, Stine; Bannert, Norbert; Bock, Claus-Thomas; Bremer, Viviane; Ross, R. Stefan; Wenz, Benjamin; Marcus, Ulrich; Zimmermann, RuthObjectives The aim of this study was to investigate the association between detention experience and hepatitis C virus (HCV) status, the role of duration and frequency of detention, and whether risk behaviours practiced ...
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2015-02-12ZeitschriftenartikelHIV-1 IN/Pol recruits LEDGF/p75 into viral particles Desimmie, Belete Ayele; Weydert, Caroline; Schrijvers, Rik; Vets, Sofie; Demeulemeester, Jonas; Proost, Paul; Paron, Igor; Rijck, Jan de; Mast, Jan; Bannert, Norbert; Gijsbers, Rik; Christ, Frauke; Debyser, ZegerBackground: The dynamic interaction between HIV and its host governs the replication of the virus and the study of the virus-host interplay is key to understand the viral lifecycle. The host factor lens epithelium-derived ...
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2019-01-08ZeitschriftenartikelHIV-1 molecular transmission clusters in nine European countries and Canada: association with demographic and clinical factors Paraskevis, Dimitrios; Beloukas, Apostolos; Stasinos, Kostantinos; Pantazis, Nikos; de Mendoza, Carmen; Bannert, Norbert; Meyer, Laurence; Zangerle, Robert; Gill, John; Prins, Maria; d'Arminio Montforte, Antonella; Bakken Kran, Anne-Marte; Porter, Kholoud; Touloumi, GiotaBackground Knowledge of HIV-1 molecular transmission clusters (MTCs) is important, especially in large-scale datasets, for designing prevention programmes and public health intervention strategies. We used a large-scale ...
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2019-12-05ZeitschriftenartikelHIV-Studien und HIV-Projekte am Robert Koch-Institut Koppe, Uwe; Hanke, Kirsten; Fiebig, Uwe; Schmidt, Daniel; Meixenberger, Karolin; Pantke, Annemarie; Gunsenheimer-Bartmeyer, Barbara; Kollan, Christian; Kühne, Andrea; Marcus, Ulrich; Bannert, Norbert; Bremer, VivianeNeben der gesetzlich geregelten Surveillance von HIV-Neudiagnosen in Deutschland erfolgt am RKI auch die Durchführung verschiedener Studienprojekte, die im Epidemiologischen Bulletin 49/2019 vorgestellt werden. Das Rückgrat ...
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2013-11-19ZeitschriftenartikelIdentification of late assembly domains of the human endogenous retrovirus-K(HML-2) Chudak, Claudia; Beimforde, Nadine; George, Maja; Zimmermann, Anja; Lausch, Veronika; Hanke, Kirsten; Bannert, NorbertBackground: Late assembly (L)-domains are protein interaction motifs, whose dysfunction causes characteristic budding defects in enveloped viruses. Three different amino acid motifs, namely PT/SAP, PPXY and YPXnL have ...
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2011-05-09ZeitschriftenartikelIdentification of the protease cleavage sites in a reconstituted Gag polyprotein of an HERV-K(HML-2) element George, Maja; Schwecke, Torsten; Beimforde, Nadine; Hohn, Oliver; Chudak, Claudia; Zimmermann, Anja; Kurth, Reinhard; Naumann, Dieter; Bannert, NorbertBackground: The human genome harbors several largely preserved HERV-K(HML-2) elements. Although this retroviral family comes closest of all known HERVs to producing replication competent virions, mutations acquired during ...
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2014-06-03ZeitschriftenartikelImproved Testing of Recent HIV-1 Infections with the BioRad Avidity Assay Compared to the Limiting Antigen Avidity Assay and BED Capture Enzyme Immunoassay: Evaluation Using Reference Sample Panels from the German Seroconverter Cohort Hauser, Andrea; Santos-Hövener, Claudia; Meixenberger, Karolin; Zimmermann, Ruth; Somogyi, Sybille; Fiedler, Stefan; Hofmann, Alexandra; Bartmeyer, Barbara; Jansen, Klaus; Hamouda, Osamah; Bannert, Norbert; Kücherer, ClaudiaBackground: The variety and limitations of current laboratory methods for estimating HIV-incidence has driven attempts to improve and standardize the performance of serological ‘Tests for Recent HIV-Infections’ (TRI). ...
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2015-06-19ZeitschriftenartikelIn Silico Prediction and Experimental Confirmation of HA Residues Conferring Enhanced Human Receptor Specificity of H5N1 Influenza A Viruses Schmier, Sonja; Mostafa, Ahmed; Haarmann, Thomas; Bannert, Norbert; Ziebuhr, John; Veljkovic, Veljko; Dietrich, Ursula; Pleschka, StephanNewly emerging influenza A viruses (IAV) pose a major threat to human health by causing seasonal epidemics and/or pandemics, the latter often facilitated by the lack of pre-existing immunity in the general population. Early ...
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2023-10-02ZeitschriftenartikelIncreasing hepatitis B vaccination coverage and decreasing hepatitis B co-infection prevalence among people with HIV-1 in Germany, 1996–2019. Results from a cohort study primarily in men who have sex with men Amrei, Krings; Schmidt, Daniel; Christian, Kollan; Meixenberger, Karolin; Bannert, Norbert; Tiemann, C.; Münstermann, D.; Bremer, Viviane; Gunsenheimer-Bartmeyer, BarbaraObjectives Viral hepatitis co-infection among people living with HIV is known to accelerate the progression of liver disease and AIDS. An increased prevalence and incidence of hepatitis B virus (HBV) infection among ...
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2018-11-08ZeitschriftenartikelIncreasing proportions of HIV-1 non-B subtypes and of NNRTI resistance between 2013 and 2016 in Germany: Results from the national molecular surveillance of new HIV-diagnoses Hauser, Andrea; Hofmann, Alexandra; Meixenberger, Karolin; Altmann, Britta; Hanke, Kirsten; Bremer, Viviane; Bartmeyer, Barbara; Bannert, NorbertBackground Molecular surveillance of newly diagnosed HIV-infections is important for tracking trends in circulating HIV-variants, including those with transmitted drug resistances (TDR) to sustain ART efficacy. Methods Dried ...
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2009-10-16ZeitschriftenartikelLack of evidence for xenotropic murine leukemia virus-related virus(XMRV) in German prostate cancer patients Hohn, Oliver; Krause, Hans; Barbarotto, Pia; Niederstadt, Lars; Beimforde, Nadine; Denner, Joachim; Miller, Kurt; Kurth, Reinhard; Bannert, NorbertBackground: A novel gammaretrovirus named xenotropic murine leukemia virus-related virus (XMRV) has been recently identified and found to have a prevalence of 40% in prostate tumor samples from American patients carrying ...
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2013-05-30ZeitschriftenartikelLEDGINs inhibit late stage HIV-1 replication by modulating integrase multimerization in the virions Desimmie, Belete A.; Schrijvers, Rik; Demeulemeester, Jonas; Borrenberghs, Doortje; Weydert, Caroline; Thys, Wannes; Vets, Sofie; Remoortel, Barbara van; Hofkens, Johan; Rijck, Jan de; Hendrix, Jelle; Bannert, Norbert; Gijsbers, Rik; Christ, Frauke; Debyser, ZegerBackground: LEDGINs are novel allosteric HIV integrase (IN) inhibitors that target the lens epithelium-derived growth factor (LEDGF)/p75 binding pocket of IN. They block HIV-1 integration by abrogating the interaction ...
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2011-02-10ZeitschriftenartikelMechanical damage to Gram-negative bacteria by surface plating with the Drigalski-spatula technique Hedderich, Reiner; Müller, Rolf; Greulich, Yasmin; Bannert, Norbert; Holland, Gudrun; Kaiser, Petra; Reissbrodt, RolfColony counting by spreading bacterial suspensions on plating media by various techniques is of general concern. Comparative studies between hand plating (Drigalski-spatula technique) for different time intervals and spiral ...
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2010-06-21ZeitschriftenartikelMicrotubes self-assembled from a cholesterol-modified nucleoside Pescador, Paula; Brodersen, Nicolai; Scheidt, Holger A.; Loew, Martin; Holland, Gudrun; Bannert, Norbert; Liebscher, Jürgen; Herrmann, Andreas; Huster, Daniel; Arbuzova, AnnaWe describe the formation of lipid microtubes from a novel cholesterol-modified nucleoside in binary mixture with phospholipids. Stable cylindrical structures with an outer diameter of 2–3 μm and a length of 20–40 μm were ...
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2017-11-14ZeitschriftenartikelMolecular evolution of HIV-1 integrase during the 20 years prior to the first approval of integrase inhibitors Meixenberger, Karolin; Yousef, Kaveh Pouran; Smith, Maureen Rebecca; Somogyi, Sybille; Fiedler, Stefan; Bartmeyer, Barbara; Hamouda, Osamah; Bannert, Norbert; Kleist, Max von; Kücherer, ClaudiaBackground: Detailed knowledge of the evolutionary potential of polymorphic sites in a viral protein is important for understanding the development of drug resistance in the presence of an inhibitor. We therefore set ...