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Auflistung nach Autor "Dobrindt, Ulrich"
Anzeige der Publikationen 1-8 von 8
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2011-01-04ZeitschriftenartikelChromosomal instability in enterohaemorrhagic Escherichia coli O157:H7: impact on adherence, tellurite resistance and colony phenotype. Bielaszewska, Martina; Middendorf, Barbara; Tarr, Phillip I.; Zhang, Wenlan; Prager, Rita; Aldick, Thomas; Dobrindt, Ulrich; Karch, Helge; Mellmann, AlexanderTellurite (Tel) resistant enterohaemorrhagic Escherichia coli (EHEC) O157:H7 is a global pathogen. In strain EDL933 Tel resistance (Tel(R) ) is encoded by duplicate ter cluster in O islands (OI) 43 and 48, which also harbour ...
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2016-09-12ZeitschriftenartikelCombined Analysis of Variation in Core, Accessory and Regulatory Genome Regions Provides a Super-Resolution View into the Evolution of Bacterial Populations McNally, Alan; Oren, Yaara; Kelly, Darren; Pascoe, Ben; Dunn, Steven; Sreecharan, Tristan; Vehkala, Minna; Välimäki, Niko; Prentice, Michael B.; Ashour, Amgad; Avram, Oren; Pupko, Tal; Dobrindt, Ulrich; Literak, Ivan; Guenther, Sebastian; Schaufler, Katharina; Wieler, Lothar H.; Zhiyong, Zong; Sheppard, Samuel K.; McInerney, James O.; Corander, JukkaThe use of whole-genome phylogenetic analysis has revolutionized our understanding of the evolution and spread of many important bacterial pathogens due to the high resolution view it provides. However, the majority of ...
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2014-01-10ZeitschriftenartikelHeteropathogenic virulence and phylogeny reveal phased pathogenic metamorphosis in Escherichia coli O2:H6 Bielaszewska, Martina; Schiller, Roswitha; Lammers, Lydia; Bauwens, Andreas; Fruth, Angelika; Middendorf, Barbara; Schmidt, Alexander; Tarr, Phillip I.; Dobrindt, Ulrich; Karch, Helge; Mellmann, AlexanderExtraintestinal pathogenic and intestinal pathogenic (diarrheagenic) Escherichia coli differ phylogenetically and by virulence profiles. Classic theory teaches simple linear descent in this species, where non-pathogens ...
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2010-10-21ZeitschriftenartikelHigh-throughput microarray technology in diagnostics of enterobacteria based on genome-wide probe selection and regression analysis Friedrich, Torben; Rahmann, Sven; Weigel, Wilfried; Rabsch, Wolfgang; Fruth, Angelika; Ron, Eliora; Gunzer, Florian; Dandekar, Thomas; Hacker, Jörg; Müller, Tobias; Dobrindt, UlrichBackground: The Enterobacteriaceae comprise a large number of clinically relevant species with several individual subspecies. Overlapping virulence-associated gene pools and the high overall genome plasticity often ...
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2017-02-03ZeitschriftenartikelHost cell interactions of outer membrane vesicle-associated virulence factors of enterohemorrhagic Escherichia coli O157: Intracellular delivery, trafficking and mechanisms of cell injury Bielaszewska, Martina; Rüter, Christian; Bauwens, Andreas; Greune, Lilo; Jarosch, Kevin-André; Steil, Daniel; Zhang, Wenlan; He, Xiaohua; Lloubes, Roland; Fruth, Angelika; Kim, Kwang Sik; Schmidt, M. Alexander; Dobrindt, Ulrich; Mellmann, Alexander; Karch, HelgeOuter membrane vesicles (OMVs) are important tools in bacterial virulence but their role in the pathogenesis of infections caused by enterohemorrhagic Escherichia coli (EHEC) O157, the leading cause of life-threatening ...
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2021-01-15ZeitschriftenartikelThe Superior Adherence Phenotype of E. coli O104:H4 is Directly Mediated by the Aggregative Adherence Fimbriae Type I Schiller, Philipp; Knödler, Michael; Berger, Petya; Greune, Lilo; Fruth, Angelika; Mellmann, Alexander; Dersch, Petra; Berger, Michael; Dobrindt, UlrichWhereas the O104:H4 enterohemorrhagic Escherichia coli (EHEC) outbreak strain from 2011 expresses aggregative adherence fimbriae of subtype I (AAF/I), its close relative, the O104:H4 enteroaggregative Escherichia coli ...
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2015-08-18ZeitschriftenartikelVirulence from vesicles: Novel mechanisms of host cell injury by Escherichia coli O104:H4 outbreak strain Kunsmann, Lisa; Rüter, Christian; Bauwens, Andreas; Greune, Lilo; Glüder, Malte; Kemper, Björn; Fruth, Angelika; Wai, Sun Nyunt; He, Xiaohua; Lloubes, Roland; Schmidt, M. Alexander; Dobrindt, Ulrich; Mellmann, Alexander; Karch, Helge; Bielaszewska, MartinaThe highly virulent Escherichia coli O104:H4 that caused the large 2011 outbreak of diarrhoea and haemolytic uraemic syndrome secretes blended virulence factors of enterohaemorrhagic and enteroaggregative E. coli, but their ...
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2018-01-11ZeitschriftenartikelWhole-Genome Draft Sequences of Nine Asymptomatic Escherichia coli Bacteriuria Isolates from Diabetic Patients Stork, Christoph; Kovács, Beáta; Trost, Eva; Kovács, Tamás; Schneider, György; Rózsai, Barnabás; Kerényi, Monika; Emődy, Levente; Dobrindt, UlrichEscherichia coli can colonize the urinary bladder without causing a disease response in the host. This asymptomatic bacteriuria (ABU) can protect against recurrent symptomatic urinary tract infection by virulent bacteria. ...