Auflistung nach Schlagwort "Animals"
Anzeige der Publikationen 101-120 von 241
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2014-06-01ZeitschriftenartikelHuman Granulocytic Anaplasmosis Acquired in Scotland, 2013
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2009-12-21ZeitschriftenartikelIdentification of a novel betaherpesvirus in Mus musculus Rodent betaherpesviruses vary considerably in genomic content, and these variations can result in a distinct pathogenicity. Therefore, the identification of unknown betaherpesviruses in house mice (Mus musculus), the ...
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2011-05-01ZeitschriftenartikelIgY Technology: Extraction of Chicken Antibodies from Egg Yolk by Polyethylene Glycol (PEG) Precipitation Hens can be immunized by means of i.m. vaccination (Musculus pectoralis, left and right, injection volume 0.5-1.0 ml) or by means of Gene-Gun plasmid-immunization. Dependent on the immunogenicity of the antigen, high ...
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2014-07-07ZeitschriftenartikelImpact of Acinetobacter baumannii Superoxide Dismutase on Motility, Virulence, Oxidative Stress Resistance and Susceptibility to Antibiotics Acinetobacter baumannii is a Gram-negative bacterium appearing as an opportunistic pathogen in hospital settings. Superoxide dismutase (SOD) contributes to virulence in several pathogenic bacteria by detoxifying reactive ...
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2012-11-06ZeitschriftenartikelImpaired pten expression in human malignant peripheral nerve sheath tumours. Malignant peripheral nerve sheath tumours (MPNST) are aggressive sarcomas that develop in about 10% of patients with the genetic disease neurofibromatosis type 1 (NF1). Molecular alterations contributing to MPNST formation ...
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2009-02-01ZeitschriftenartikelImported malaria in children in industrialized countries, 1992-2002. Children account for an appreciable proportion of total imported malaria cases, yet few studies have quantified these cases, identified trends, or suggested evidence-based prevention strategies for this group of travelers. ...
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2015-06-19ZeitschriftenartikelIn Silico Prediction and Experimental Confirmation of HA Residues Conferring Enhanced Human Receptor Specificity of H5N1 Influenza A Viruses Newly emerging influenza A viruses (IAV) pose a major threat to human health by causing seasonal epidemics and/or pandemics, the latter often facilitated by the lack of pre-existing immunity in the general population. Early ...
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2010-05-24ZeitschriftenartikelInducible costimulator (ICOS) blockade inhibits accumulation of polyfunctional T helper 1/T helper 17 cells and mitigates autoimmune arthritis Objectives: Inducible costimulator (ICOS) and its ligand (ICOSL) regulate T and B cell responses. Glucose-6-phosphate isomerase (G6PI)-induced arthritis requires T and B lymphocytes. It was hypothesised that blocking ...
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2012-04-01ZeitschriftenartikelInfection Barriers to Successful Xenotransplantation Focusing on Porcine Endogenous Retroviruses Xenotransplantation may be a solution to overcome the shortage of organs for the treatment of patients with organ failure, but it may be associated with the transmission of porcine microorganisms and the development of ...
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2014-01-02ZeitschriftenartikelInflammation Fuels Colicin Ib-Dependent Competition of Salmonella Serovar Typhimurium and E. coli in Enterobacterial Blooms The host's immune system plays a key role in modulating growth of pathogens and the intestinal microbiota in the gut. In particular, inflammatory bowel disorders and pathogen infections induce shifts of the resident commensal ...
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2008-11-07ZeitschriftenartikelInfluenza A Virus Inhibits Type I IFN Signaling via NF-κB-Dependent Induction of SOCS-3 Expression The type I interferon (IFN) system is a first line of defense against viral infections. Viruses have developed various mechanisms to counteract this response. So far, the interferon antagonistic activity of influenza A ...
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2009-06-12ZeitschriftenartikelInfluenza B virus ribonucleoprotein is a potent activator of the antiviral kinase PKR Activation of the latent kinase PKR is a potent innate defense reaction of vertebrate cells towards viral infections, which is triggered by recognition of viral double-stranded (ds) RNA and results in a translational ...
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2011-09-14ZeitschriftenartikelInfluenza B Virus With Modified Hemagglutinin Cleavage Site as a Novel Attenuated Live Vaccine Background: Both pandemic and interpandemic influenza is associated with high morbidity and mortality worldwide. Seasonal epidemics are caused by both influenza A and B virus strains that cocirculate with varying predominance ...
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2011-09-01ZeitschriftenartikelInfluenza Virus Ribonucleoprotein Complexes Gain Preferential Access to Cellular Export Machinery through Chromatin Targeting In contrast to most RNA viruses, influenza viruses replicate their genome in the nucleus of infected cells. As a result, newly-synthesized vRNA genomes, in the form of viral ribonucleoprotein complexes (vRNPs), must be ...
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2008-05-28ZeitschriftenartikelInterspecies transmission of simian foamy virus in a natural predator-prey system Simian foamy viruses (SFV) are ancient retroviruses of primates and have coevolved with their host species for as many as 30 million years. Although humans are not naturally infected with foamy virus, infection is occasionally ...
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2011-04-29ZeitschriftenartikelIntra- and Interspecies Genomic Transfer of the Enterococcus faecalis Pathogenicity Island Enterococci are the third leading cause of hospital associated infections and have gained increased importance due to their fast adaptation to the clinical environment by acquisition of antibiotic resistance and pathogenicity ...
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2011-03-31ZeitschriftenartikelIS element IS16 as a molecular screening tool to identify hospital-associated strains of Enterococcus faecium Background: Hospital strains of Enterococcus faecium could be characterized and typed by various molecular methods (MLST, AFLP, MLVA) and allocated to a distinct clonal complex known as MLST CC17. However, these techniques ...
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2012-08-14ZeitschriftenartikelIsolation and characterization of three Mammalian orthoreoviruses from European bats. In recent years novel human respiratory disease agents have been described in South East Asia and Australia. The causative pathogens were classified as pteropine orthoreoviruses with strong phylogenetic relationship to ...
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2011-03-16ZeitschriftenartikelJoint production of prime/boost pairs of Fowlpox Virus and Modified Vaccinia Ankara recombinants carrying the same transgene Pairs of recombinant MVA (Modified Vaccinia Ankara) and FPV (Fowlpox Virus) expressing the same transgene are reasonable candidates for prime/boost regimens, because cross-reacting immune responses between the two vectors, ...
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2008-03-10ZeitschriftenartikelKnockdown of porcine endogenous retrovirus (PERV) expression by PERV-specific shRNA in transgenic pigs Background: Xenotransplantation using porcine cells, tissues or organs may be associated with the transmission of porcine endogenous retroviruses (PERVs). More than 50 viral copies have been identified in the pig genome ...