Browsing by Subject "610 Medizin und Gesundheit"
Now showing items 1461-1480 of 6049
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2021-09-21ZeitschriftenartikelGenetic diversification of persistent Mycobacterium abscessus within cystic fibrosis patients Mycobacterium (M.) abscessus infections in Cystic Fibrosis (CF) patients cause a deterioration of lung function. Treatment of these multidrug-resistant pathogens is associated with severe side-effects, while frequently ...
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2019-11-06ZeitschriftenartikelGenetic Diversity and Spatial Segregation of Francisella tularensis Subspecies holarctica in Germany Francisella tularensis is an intracellular pleomorphic bacterium and the causative agent of tularemia, a zoonotic disease with a wide host range. Among the F. tularensis subspecies, especially F. tularensis subsp. holarctica ...
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2022-12-21ZeitschriftenartikelGenetic diversity in the metronidazole metabolism genes nitroreductases and pyruvate ferredoxin oxidoreductases in susceptible and refractory clinical samples of Giardia lamblia The effectiveness of metronidazole against the tetraploid intestinal parasite Giardia lamblia is dependent on its activation/inactivation within the cytoplasm. There are several activating enzymes, including pyruvate ...
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2021-03-24ZeitschriftenartikelGenetic Diversity of Enteric Viruses in Children under Five Years Old in Gabon Enteric viruses are the leading cause of diarrhea in children globally. Identifying viral agents and understanding their genetic diversity could help to develop effective preventive measures. This study aimed to determine ...
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2020-12-18ZeitschriftenartikelGenetic Diversity of the Flavohemoprotein Gene of Giardia lamblia: Evidence for High Allelic Heterozygosity and Copy Number Variation Purpose: The flavohemoprotein (gFlHb) in Giardia plays an important role in managing nitrosative and oxidative stress, and potentially also in virulence and nitroimidazole drug tolerance. The aim of this study was to analyze ...
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2023-02-01Berichte und sonstige TexteGenetic Organization of Acquired Antimicrobial Resistance Genes and Detection of Resistance-Mediating Mutations in a Gallibacterium anatis Isolate from a Calf Suffering from a Respiratory Tract Infection Gallibacterium (G.) anatis isolates associated with respiratory diseases in calves and har- boring acquired antimicrobial resistance genes have been described in Belgium. The aim of this study was to analyze the genetic ...
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2019-05-10ZeitschriftenartikelGenetic variation in metronidazole metabolism and oxidative stress pathways in clinical Giardia lamblia assemblage A and B isolates Purpose: Treatment-refractory Giardia cases have increased rapidly within the last decade. No markers of resistance nor a standardized susceptibility test have been established yet, but several enzymes and their pathways ...
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2019-11-15ZeitschriftenartikelGenetic, Epigenetic and Phenotypic Diversity of Four Bacillus velezensis Strains Used for Plant Protection or as Probiotics Bacillus velezensis strains are applied as ecologically safe biopesticides, plant growth promoting rhizobacteria (PGPR), and in veterinary probiotics. They are abundant in various environments including soil, plants, marine ...
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2019-01Berichte und sonstige TexteGenetische Beratung und Inanspruchnahme GenBIn2 Die genetische Beratung wird durch das Gendiagnostikgesetz und die Richtlinie über die Anforderungen an die Qualifikation zur und Inhalte der genetischen Beratung der Gendiagnostik-Kommission beim Robert Koch-Institut ...
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2021-02-02Berichte und sonstige TexteGenetische Reihenuntersuchung zur Früherkennung der 5q-assoziierten spinalen Muskelatrophie im Rahmen des Erweiterten Neugeborenen-Screenings Die Gendiagnostik-Kommission (GEKO) hat die vom Gemeinsamen Bundesausschusses (G-BA) abgestimmten Unterlagen vom 17.12.2020 zum „Neugeborenen-Screening auf 5q-assoziierte spinale Muskelatrophie“ gemäß § 16 Abs. 2 ...
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2021-02-02Berichte und sonstige TexteGenetische Reihenuntersuchung zur Früherkennung der Sichelzellkrankheit im Rahmen des Erweiterten Neugeborenen-Screenings Stellungnahme der GEKO gemäß § 16 Abs. 2 GenDGDie Gendiagnostik-Kommission (GEKO) hat die vom Gemeinsamen Bundesausschusses (G-BA) abgestimmten Unterlagen vom 20.11.2020 zum „Screening auf Sichelzellkrankheit bei Neugeborenen“ gemäß § 16 Abs. 2 Gendiagnostikgesetz ...
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2017-11-24Berichte und sonstige TexteGenetische Reihenuntersuchung zur Früherkennung der Tyrosinämie Typ I mittels Tandem-Massenspektrometrie im Rahmen des Erweiterten Neugeborenen-Screenings Stellungnahme der GEKO gemäß § 16 Abs. 2 GenDG
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2018-12-20Berichte und sonstige TexteGenetische Reihenuntersuchung zur Früherkennung von SCID im Rahmen des Erweiterten Neugeborenen-Screenings Stellungnahme der GEKO gemäß § 16 Abs. 2 GenDG
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2022-02-22ZeitschriftenartikelGenome sequence data of Bacillus velezensis BP1.2A and BT2.4 Here, we report the complete genome sequence data of the biocontrol strains Bacillus velezensis BP1.2A and BT2.4 isolated from Vietnamese crop plants. The size of the genomes is 3,916,868 bp (BP1.2A), and 3,922,686 bp ...
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2021-01-19ZeitschriftenartikelGenome-Based Analyses of Fitness Effects and Compensatory Changes Associated with Acquisition of blaCMY-, blaCTX-M-, and blaOXA-48/VIM-1-Containing Plasmids in Escherichia coli Background: Resistance plasmids are under selective conditions beneficial for the bacterial host, but in the absence of selective pressure, this carriage may cause fitness costs. Compensation of this fitness burden is ...
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2018-05-02ZeitschriftenartikelGenome-based analysis of Carbapenemase-producing Klebsiella pneumoniae isolates from German hospital patients, 2008-2014 Background By using whole genome sequence data we aimed at describing a population snapshot of carbapenemase-producing K. pneumoniae isolated from hospitalized patients in Germany between 2008 and 2014. Methods We ...
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2021-05-08ZeitschriftenartikelGenome-Based Analysis of Klebsiella spp. Isolates from Animals and Food Products in Germany, 2013–2017 The increase in infections with multidrug-resistant and virulent Klebsiella pneumoniae (K. pneumoniae) strains poses a serious threat to public health. However, environmental reservoirs and routes of transmission for ...
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2020-03-09ZeitschriftenartikelGenome-based Salmonella serotyping as the new gold standard Salmonella enterica is the second most reported bacterial cause of food-borne infections in Europe. Therefore molecular surveillance activities based on pathogen subtyping are an important measure of controlling Salmonellosis ...
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2021-02-15ZeitschriftenartikelGenome-Wide Association Studies for the Detection of Genetic Variants Associated With Daptomycin and Ceftaroline Resistance in Staphylococcus aureus Background: As next generation sequencing (NGS) technologies have experienced a rapid development over the last decade, the investigation of the bacterial genetic architecture reveals a high potential to dissect causal ...
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2021-05-14ZeitschriftenartikelGenome‑wide insights into population structure and host specifcity of Campylobacter jejuni The zoonotic pathogen Campylobacter jejuni is among the leading causes of foodborne diseases worldwide. While C. jejuni colonises many wild animals and livestock, persistence mechanisms enabling the bacterium to adapt to ...