Auflistung nach Schlagwort "Animals"
Anzeige der Publikationen 221-240 von 241
-
2008-06-10ZeitschriftenartikelThe mycobacterial DNA-binding protein 1 (MDP1) from Mycobacterium bovis BCG influences various growth characteristics Background: Pathogenic mycobacteria such as M. tuberculosis, M. bovis or M. leprae are characterised by their extremely slow growth rate which plays an important role in mycobacterial virulence and eradication of the ...
-
2013-10-08ZeitschriftenartikelThe Novel Human Influenza A(H7N9) Virus Is Naturally Adapted to Efficient Growth in Human Lung Tissue A novel influenza A virus (IAV) of the H7N9 subtype has been isolated from severely diseased patients with pneumonia and acute respiratory distress syndrome and, apparently, from healthy poultry in March 2013 in Eastern ...
-
2010-11-10ZeitschriftenartikelThe Presence of a vpu Gene and the Lack of Nef-Mediated Downmodulation of T Cell Receptor-CD3 Are Not Always Linked in Primate Lentiviruses Nef is an accessory protein critical for the ability of human and simian immunodeficiency viruses (HIV and SIV) to replicate efficiently in their respective hosts. Previous analyses of members of 15 different primate ...
-
2011-06-30ZeitschriftenartikelThe spread of fecally transmitted parasites in socially-structured populations. Mammals are infected by a wide array of gastrointestinal parasites, including parasites that also infect humans and domesticated animals. Many of these parasites are acquired through contact with infectious stages present ...
-
2013-08-07ZeitschriftenartikelThe Transmembrane Protein of the Human Endogenous Retrovirus - K (HERV-K) Modulates Cytokine Release and Gene Expression Numerous copies of endogenous retroviruses are present in the genome of mammals including man. Although most of them are defective, some, e.g., the human endogenous retroviruses HERV-K, were found to be expressed under ...
-
2010-01-23ZeitschriftenartikelTick burden on European roe deer (Capreolus capreolus) In our study we assessed the tick burden on roe deer (Capreolus capreolus L.) in relation to age, physical condition, sex, deer density and season. The main objective was to find predictive parameters for tick burden. In ...
-
2011-09-29ZeitschriftenartikelTick-borne encephalitis in Europe, 2007 to 2009 As a follow-up of a retrospective survey on tick borneencephalitis (TBE) in 2008, the European Network for Diagnostics of “Imported” Viral Diseases launched a new survey in 2010, to collect broader information on TBE ...
-
2014-05-08ZeitschriftenartikelTimed Action of IL-27 Protects from Immunopathology while Preserving Defense in Influenza Infection with influenza virus can result in massive pulmonary infiltration and potentially fatal immunopathology. Understanding the endogenous mechanisms that control immunopathology could provide a key to novel adjunct ...
-
2012-07-20ZeitschriftenartikelTools for cellular immunology and vaccine research the in the guinea pig: Monoclonal antibodies to cell surface antigens and cell lines The use of monoclonal antibodies directed against membrane proteins of leukocytes has greatly contributed to our understanding of the function and development of the immune system. Meanwhile these reagents provide valuable ...
-
2011-01-01ZeitschriftenartikelTowards an AIDS vaccine: The transmembrane envelope protein as target for broadly neutralizing antibodies Although the development of an effective vaccine is the main goal in the fight against AIDS, all attempts by numerous laboratories to develop a vaccine have failed so far. In addition, it is still unclear whether cytotoxic ...
-
2013-03-11ZeitschriftenartikelTowards further reduction and replacement of animal bioassays in prion research by cell and protein misfolding cyclic amplification assays Laboratory animals have long since been used extensively in bioassays for prions in order to quantify, usually in terms of median infective doses [ID50], how infectious these pathogens are in vivo. The identification of ...
-
2011-03-31ZeitschriftenartikelTrends in Imported Chikungunya Virus Infections in Germany, 2006–2009 Chikungunya virus (CHIKV) has been previously reported in many African and Asian areas, but it recently reemerged strongly in countries bordering the Indian Ocean as well as caused an outbreak in northern Italy. In Germany, ...
-
2012-12-20ZeitschriftenartikelTreponema pallidum Infection in the Wild Baboons of East Africa: Distribution and Genetic Characterization of the Strains Responsible It has been known for decades that wild baboons are naturally infected with Treponema pallidum, the bacterium that causes the diseases syphilis (subsp. pallidum), yaws (subsp. pertenue), and bejel (subsp. endemicum) in ...
-
2014-04-21ZeitschriftenartikelTwo Novel EHEC/EAEC Hybrid Strains Isolated from Human Infections The so far highest number of life-threatening hemolytic uremic syndrome was associated with a food-borne outbreak in 2011 in Germany which was caused by an enterohemorrhagic Escherichia coli (EHEC) of the rare serotype ...
-
2013-03-21ZeitschriftenartikelTyping of Salmonella enterica serovar Infantis isolates from 51 outbreaks in Germany between 1974 and 2009 by a novel phage-typing scheme We developed a new phage-typing method and evaluated its application in combination with XbaI macrorestriction analysis by pulsed-field gel electrophoresis (PFGE) as a useful tool for the long-term epidemiology of Salmonella ...
-
2011-07-07ZeitschriftenartikelUnique cell adhesion and invasion properties of Yersinia enterocolitica O:3, the most frequent cause of human Yersiniosis. Many enteric pathogens are equipped with multiple cell adhesion factors which are important for host tissue colonization and virulence. Y. enterocolitica, a common food-borne pathogen with invasive properties, uses the ...
-
2011-08-04ZeitschriftenartikelUsutu virus – potential risk of human disease in Europe Usutu virus (USUV) is an African mosquito-borne flavivirus, member of the Japanese encephalitis antigenic group. This avian virus is transmitted by arthropod vectors (mainly mosquitoes of the Culex pipiens complex). It is ...
-
2011-01-01ZeitschriftenartikelVaccines for Leishmaniasis: From proteome to vaccine candidates Leishmania spp. cause a wide spectrum of tropical diseases which are threatening an estimated 350 million people around the globe. While in most cases non-fatal, the disease is associated with high morbidity, social stigmata ...
-
2010-08-04ZeitschriftenartikelVirulence Determinants of Avian H5N1 Influenza A Virus in Mammalian and Avian Hosts: Role of the C-Terminal ESEV Motif in the Viral NS1 Protein We assessed the prediction that access of the viral NS1 protein to cellular PDZ domain protein networks enhances the virulence of highly pathogenic avian influenza A viruses. The NS1 proteins of most avian influenza viruses ...
-
2010-08-01ZeitschriftenartikelWhite-Nose Syndrome Fungus (Geomyces destructans) in Bats, Europe White-nose syndrome is an emerging disease in North America that has caused substantial declines in hibernating bats. A recently identified fungus (Geomyces destructans) causes skin lesions that are characteristic of this ...