Browsing by Subject "H5N1 Subtype/genetics"

Now showing items 1-2 of 2

2011-03-16Zeitschriftenartikel

Joint production of prime/boost pairs of Fowlpox Virus and Modified Vaccinia Ankara recombinants carrying the same transgene

Soprana, Elisa; Panigada, Maddalena; Knauf, Mathias; Radaelli, Antonia; Vigevani, Luisa; Palini, Alessio; Villa, Chiara; Malnati, Mauro; Cassina, Giulia; Kurth, Reinhard; Norley, Stephen; Siccardi, Antonio G.

Pairs of recombinant MVA (Modified Vaccinia Ankara) and FPV (Fowlpox Virus) expressing the same transgene are reasonable candidates for prime/boost regimens, because cross-reacting immune responses between the two vectors, ...
2010-08-04Zeitschriftenartikel

Virulence Determinants of Avian H5N1 Influenza A Virus in Mammalian and Avian Hosts: Role of the C-Terminal ESEV Motif in the Viral NS1 Protein

Zielecki, Florian; Semmler, Ilia; Kalthoff, Donata; Voss, Daniel; Mauel, Susanne; Gruber, Achim D.; Beer, Martin; Wolff, Thorsten

We assessed the prediction that access of the viral NS1 protein to cellular PDZ domain protein networks enhances the virulence of highly pathogenic avian influenza A viruses. The NS1 proteins of most avian influenza viruses ...