Browsing by Subject "HERV-K"
Now showing items 1-5 of 5
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2006-09-01DissertationExpression und biologische Funktion von humanen endogenen Retroviren (HERVs), insbesondere von HERV-K Daten des humanen Genomprojektes zeigen, dass ca. 8% des gesamten humanen Genoms aus retroviralen Sequenzen besteht. Der überwiegende Teil dieser Proviren ist aufgrund verschiedener Mutationen defekt. Im Gegensatz zu ...
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2014-03-19ZeitschriftenartikelExpression-analysis of the human endogenous retrovirus HERV-K in human astrocytic tumors Background: The human endogenous retrovirus K (HERV-K) has been acquired by the genome of human ancestors million years ago. It is the most complete of the HERVs with transcriptionally active gag, pol and env genes. ...
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2013-09-20ZeitschriftenartikelHERV-K(HML-2), the best preserved family of HERVs: endogenization, expression, and implications in health and disease Retroviruses that have the ability to infect germ line cells can become an integral and inherited part of the host genome. About 8% of the human chromosomal DNA consists of sequences derived from infections by retroviruses ...
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2018-02-13ZeitschriftenartikelHERVs New Role in Cancer: From Accused Perpetrators to Cheerful Protectors Initial indications that retroviruses are connected to neoplastic transformation were seen more than a century ago. This concept has also been tested for endogenized retroviruses (ERVs) that are abundantly expressed in ...
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2011-08-15ZeitschriftenartikelHuman endogenous retrovirus K (HERV-K) is expressed in villous and extravillous cytotrophoblast cells of the human placenta Human endogenous retroviruses (HERVs) have been shown to be important in physiological and pathophysiological processes in humans. Several HERVs have been found to be expressed in the placenta—a tissue with special ...