Browsing by Subject "Mutation/genetics"
Now showing items 1-3 of 3
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2016-01-12ZeitschriftenartikelA Follow-Up of the Multicenter Collaborative Study on HIV-1 Drug Resistance and Tropism Testing Using 454 Ultra Deep Pyrosequencing Background: Ultra deep sequencing is of increasing use not only in research but also in diagnostics. For implementation of ultra deep sequencing assays in clinical laboratories for routine diagnostics, intra- and ...
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2012-09-27ZeitschriftenartikelConfidence-based Somatic Mutation Evaluation and Prioritization Next generation sequencing (NGS) has enabled high throughput discovery of somatic mutations. Detection depends on experimental design, lab platforms, parameters and analysis algorithms. However, NGS-based somatic mutation ...
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2010-05-04ZeitschriftenartikelIsotopologue Profiling of Legionella pneumophila Role of Serine and Glucose as Carbon SubstratesLegionella pneumophila (Lp) is commonly found in freshwater habitats but is also the causative agent of Legionnaires' disease when infecting humans. Although various virulence factors have been reported, little is known ...