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Browsing by Subject "OCRL"

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    • 2021-11-02Zeitschriftenartikel
      SdhA blocks disruption of the Legionella-containing vacuole by hijacking the OCRL phosphatase 
      Choi, Won Young; Kim, Seongok; Aurass, Philipp; Huo, Wenwen; Creasey, Elizabeth A.; Edwards, Marc; Lowe, Martin; Isberg, Ralph R.
      Legionella pneumophila grows intracellularly within a replication vacuole via action of Icm/Dot-secreted proteins. One such protein, SdhA, maintains the integrity of the vacuolar membrane, thereby preventing cytoplasmic ...
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