Browsing by Subject "T cells"

Now showing items 1-2 of 2

2016-11-25Zeitschriftenartikel

Characterization of guinea pig T cell responses elicited after EP-assisted delivery of DNA vaccines to the skin

Schultheis, Katherine; Schäfer, Hubert; Yung, Bryan S.; Oh, Janet; Muthumani, Karuppiah; Humeau, Laurent; Broderick, Kate E.; Smith, Trevor R.F.

The skin is an ideal target tissue for vaccine delivery for a number of reasons. It is highly accessible, and most importantly, enriched in professional antigen presenting cells. Possessing strong similarities to human ...
2021-12-23Zeitschriftenartikel

Numerical approaches for the rapid analysis of prophylactic efficacy against HIV with arbitrary drug-dosing schemes

Zhang, Lanxin; Wang, Junyu; von Kleist, Max

Pre-exposure prophylaxis (PrEP) is an important pillar to prevent HIV transmission. Because of experimental and clinical shortcomings, mathematical models that integrate pharmacological, viral- and host factors are ...