Browsing by Subject "T-Lymphocytes"

Now showing items 1-2 of 2

2011-02-16Zeitschriftenartikel

Highly conserved serine residue 40 in HIV-1 p6 regulates capsid processing and virus core assembly

Votteler, Jörg; Neumann, Liane; Hahn, Sabine; Hahn, Friedrich; Rauch, Pia; Schmidt, Kerstin; Studtrucker, Nicole; Solbak, Sara MØ; Fossen, Torgils; Henklein, Peter; Ott, David E.; Holland, Gudrun; Bannert, Norbert; Schubert, Ulrich

Background: The HIV-1 p6 Gag protein regulates the final abscission step of nascent virions from the cell membrane by the action of two late assembly (L-) domains. Although p6 is located within one of the most polymorphic ...
2010-05-24Zeitschriftenartikel

Inducible costimulator (ICOS) blockade inhibits accumulation of polyfunctional T helper 1/T helper 17 cells and mitigates autoimmune arthritis

Frey, Oliver; Meisel, Juliane; Hutloff, Andreas; Bonhagen, Kerstin; Bruns, Lisa; Kroczek, Richard; Morawietz, Lars; Kamradt, Thomas

Objectives: Inducible costimulator (ICOS) and its ligand (ICOSL) regulate T and B cell responses. Glucose-6-phosphate isomerase (G6PI)-induced arthritis requires T and B lymphocytes. It was hypothesised that blocking ...