2011-11-18Zeitschriftenartikel
Synergistic Adaptive Mutations in the Hemagglutinin and Polymerase Acidic Protein Lead to Increased Virulence of Pandemic 2009 H1N1 Influenza A Virus in Mice
Seyer, Roman; Hrincius, Eike R.; Ritzel, Dorothea; Abt, Marion; Mellmann, Alexander; Marjuki, Henju; Kühn, Joachim; Wolff, Thorsten; Ludwig, Stephan; Ehrhardt, Christina
Influenza impressively reflects the paradigm of a viral disease in which continued evolution of the virus is of paramount importance for annual epidemics and occasional pandemics in humans. Because of the continuous threat ...
