2022-03-16Zeitschriftenartikel
Phylogenetic estimation of the viral fitness landscape of HIV-1 set-point viral load
Zhao, Lele; Wymant, Chris; Blanquart, François; Golubchik, Tanya; Gall, Astrid; Bakker, Margreet; Bezemer, Daniela; Hall, Matthew; Hoe Ong, Swee; Albert, Jan; Bannert, Norbert; Fellay, Jacques; Grabowski, M. Kate; Gunsenheimer-Bartmeyer, Barbara; Günthard, Huldrych F.; Kivelä, Pia; Kouyos, Roger D.; Laeyendecker, Oliver; Meyer, Laurence; Porter, Kholoud; van Sighem, Ard; van der Valk, Marc; Berkhout, Ben; Kellam, Paul; Cornelissen, Marion; Reiss, Peter; Fraser, Christophe; Ferretti, Luca; on behalf of the BEEHIVE Collaboration
Set-point viral load (SPVL), a common measure of human immunodeficiency virus (HIV)-1 virulence, is partially determined by viral genotype. Epidemiological evidence suggests that this viral property has been under stabilising ...