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Auflistung nach Autor "Ellerbrok, Heinz"
Anzeige der Publikationen 1-20 von 33
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2006-01-27ZeitschriftenartikelA New Bacillus anthracis Found in Wild Chimpanzees and a Gorilla from West and Central Africa Leendertz, Fabian; Yumlu, Saniye; Pauli, Georg; Boesch, Christophe; Couacy-Hymann, Emmanuel; Vigilant, Linda; Junglen, Sandra; Schenk, Svenja; Ellerbrok, Heinz
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2010-04-29ZeitschriftenartikelA Novel Highly Reproducible and Lethal Nonhuman Primate Model for Orthopox Virus Infection Kramski, Marit; Mätz-Rensing, Kerstin; Stahl-Hennig, Christiane; Kaup, Franz-Josef; Nitsche, Andreas; Pauli, Georg; Ellerbrok, HeinzThe intentional re-introduction of Variola virus (VARV), the agent of smallpox, into the human population is of great concern due its bio-terroristic potential. Moreover, zoonotic infections with Cowpox (CPXV) and Monkeypox ...
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2011-06-14ZeitschriftenartikelAn insect nidovirus emerging from a primary tropical rainforest. Zirkel, Florian; Kurth, Andreas; Quan, Phenix-Lan; Briese, Thomas; Ellerbrok, Heinz; Pauli, Georg; Leendertz, Fabian; Lipkin, W. Ian; Ziebuhr, John; Drosten, Christian; Junglen, SandraTropical rainforests show the highest level of terrestrial biodiversity and may be an important contributor to microbial diversity. Exploitation of these ecosystems may foster the emergence of novel pathogens. We report ...
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2006-08-09ZeitschriftenartikelAnthrax in Western and Central African Great Apes Leendertz, Fabian; Lankester, Felix; Guislain, Patrick; Néel, Cécile; Drori, Ofir; Dupain, Jef; Speede, Sheri; Reed, Patricia; Wolfe, Nathan D.; Loul, Severin; Mpoudi-Ngole, E.; Peeters, Martine; Boesch, Christophe; Pauli, Georg; Ellerbrok, Heinz; Leroy, Eric M.During the period of December 2004 to January 2005, Bacillus anthracis killed three wild chimpanzees (Pan troglodytes troglodytes) and one gorilla (Gorilla gorilla gorilla) in a tropical forest in Cameroon. While this is ...
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2004-07-05ZeitschriftenartikelCharacterization of a New Simian T-Lymphotropic Virus Type 1 (STLV-1) in a Wild Living Chimpanzee (Pan troglodytes verus) from Ivory Coast: Evidence of a New STLV-1 Group? Leendertz, Fabian; Boesch, Christophe; Junglen, Sandra; Pauli, Georg; Ellerbrok, HeinzA new strain of simian T-lymphotropic virus type 1 in blood samples from a chimpanzee that lived in the tropical rainforest of Ivory Coast is described. The sequence obtained from the long terminal repeat region of the ...
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2006-07-01ZeitschriftenartikelDetection of Infectious Poxvirus Particles. Nitsche, Andreas; Stern, Daniel; Ellerbrok, Heinz; Pauli, GeorgTo enable rapid and reliable detection of poxviruses in clinical and environmental specimens, a diagnostic approach was developed to detect
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2003-11-01ZeitschriftenartikelDiagnostik von Proben bei vermuteten bioterroristischen Anschlägen Allgemeine Aspekte und grundsätzliche ErwägungenPauli, Georg; Ellerbrok, HeinzDie terroristischen Anschläge Ende 2001 in den USA rückten die Bedrohung von Menschen durch biologische Waffen in den Blickpunkt politischer Entscheidungsträger und der breiten Öffentlichkeit. In Folge der Anschläge mit ...
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2020-11-12ZeitschriftenartikelDifferential Efficacy of Novel Antiviral Substances in 3D and Monolayer Cell Culture Koban, Robert; Neumann, Markus; Nelson, Philipp P.; Ellerbrok, HeinzRepurposing of approved drugs that target host functions also important for virus replication promises to overcome the shortage of antiviral therapeutics. Mostly, virus biology including initial screening of antivirals is ...
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2010-05-01ZeitschriftenartikelDifferential expression of human endogenous retrovirus K transcripts in primary human melanocytes and melanoma cell lines after UV irradiation. Reiche, Janine; Pauli, Georg; Ellerbrok, HeinzHuman endogenous retroviruses (HERVs) are discussed as causative agents of various diseases including cancers. Expression of endogenous retroviral sequences can be induced by ultraviolet (UV) light, which is also considered ...
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2012-05-01ZeitschriftenartikelDiversity of parvovirus 4-like viruses in humans, chimpanzees, and monkeys in hunter-prey relationships. Adlhoch, Cornelia; Kaiser, Marco; Löwa, Anna; Ulrich, Markus; Forbrig, Christian; Adjogoua, Edgard Valerie; Akoua-Koffi, Chantal; Couacy-Hymann, Emmanuel; Leendertz, Siv Aina J.; Rietschel, Wolfram; Boesch, Christophe; Ellerbrok, Heinz; Leendertz, Fabian; Leendertz, FabianDuring 2010–2011, we investigated interspecies transmission of partetraviruses between predators (humans and chimpanzees) and their prey (colobus monkeys) in Côte d’Ivoire. Despite widespread infection in all species ...
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2017-11-28ZeitschriftenartikelDynamics of Pathological and Virological Findings During Experimental Calpox Virus Infection of Common Marmosets (Callithrix jacchus) Schmitt, Anne; Gan, Li Lin; Wahed, Ahmed Abd El; Shi, Tingchuan; Ellerbrok, Heinz; Kaup, Franz-Josef; Stahl-Hennig, Christiane; Mätz-Rensing, KerstinExperimental intranasal infection of marmosets (Callithrix jacchus) with calpox virus results in fatal disease. Route and dose used for viral inoculation of the test animals mimics the natural transmission of smallpox, ...
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2009-11-14ZeitschriftenartikelExamining Landscape Factors Influencing Relative Distribution of Mosquito Genera and Frequency of Virus Infection Junglen, Sandra; Kurth, Andreas; Kuehl, H.; Quan, Phenix-Lan; Ellerbrok, Heinz; Pauli, Georg; Nitsche, Andreas; Nunn, Charles L.; Rich, S. M.; Briese, Thomas; Leendertz, FabianMosquito-borne infections cause some of the most debilitating human diseases, including yellow fever and malaria, yet we lack an understanding of how disease risk scales with human-driven habitat changes. We present an ...
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2017-05-01ZeitschriftenartikelExternal quality assessment study for ebolavirus PCR-diagnostic promotes international preparedness during the 2014 – 2016 Ebola outbreak in West Africa Ellerbrok, Heinz; Jacobsen, Sonja; Patel, Pranav; Rieger, Toni; Eickmann, Markus; Becker, Stephan; Günther, Stephan; Naidoo, Dhamari; Schrick, Livia; Keeren, Kathrin; Targosz, Angelina; Teichmann, Anette; Formenty, Pierre; Niedrig, MatthiasDuring the recent Ebola outbreak in West Africa several international mobile laboratories were deployed to the mainly affected countries Guinea, Sierra Leone and Liberia to provide ebolavirus diagnostic capacity. Additionally, ...
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2009-02-28ZeitschriftenartikelFrequent foamy virus infection in free-living chimpanzees of the Taï National Park (Côte d'Ivoire) Morozov, Vladimir; Leendertz, Fabian; Junglen, Sandra; Boesch, Christophe; Pauli, Georg; Ellerbrok, HeinzFoamy viruses are frequently found in non-human primates and apes in captivity. However, data on simian foamy virus (SFV) infection in apes from the wild are limited. Necropsy specimens were collected from 14 West African ...
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2008-06-01ZeitschriftenartikelGlobal distribution of novel rhinovirus genotype. Briese, Thomas; Renwick, Neil; Venter, Marietjie; Jarman, Richard G.; Ghosh, Dhrubaa; Köndgen, Sophie; Shrestha, Sanjaya K.; Hoegh, A. Mette; Casas, Inmaculada; Adjogoua, Edgard Valerie; Akoua-Koffi, Chantal; Myint, Khin Saw; Williams, David T.; Chidlow, Glenys; Berg, Ria van den; Calvo, Cristina; Koch, Orienka; Palacios, Gustavo; Kapoor, Vishal; Villari, Joseph; Dominguez, Samuel R.; Holmes, Kathryn V.; Leendertz, Fabian; Schweiger, Brunhilde; Ellerbrok, HeinzGlobal surveillance for a novel rhinovirus genotype indicated its association with community outbreaks and pediatric respiratory disease in Africa, Asia, Australia, Europe, and North America. Molecular dating indicates ...
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2010-07-25ZeitschriftenartikelHigh prevalence of porcine Hokovirus in German wild boar populations Adlhoch, Cornelia; Kaiser, Marco; Ellerbrok, Heinz; Pauli, GeorgPorcine Hokovirus (PHoV) was recently discovered in Hong Kong. This new Parvovirus of pigs is closely related to the human Parvoviruses 4 and 5 (PARV4/5) and bovine Hokovirus (BHoV). So far, nothing is known about the ...
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2011-02-10ZeitschriftenartikelHighly sensitive detection of the group A Rotavirus using Apolipoprotein H-coated ELISA plates compared to quantitative real-time PCR Adlhoch, Cornelia; Kaiser, Marco; Hoehne, Marina; Marques, Andreas Mas; Stefas, Ilias; Veas, Francisco; Ellerbrok, HeinzBackground: The principle of a capture ELISA is binding of specific capture antibodies (polyclonal or monoclonal) to the surface of a suitable 96 well plate. These immobilized antibodies are capable of specifically binding ...
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2006-01-19ZeitschriftenartikelHighly sensitive real-time PCR for specific detection and quantification of Coxiella burnetii Klee, Silke; Tyczka, Judith; Ellerbrok, Heinz; Franz, Tatjana; Linke, Sonja; Baljer, Georg; Appel, BerndBackground: Coxiella burnetii, the bacterium causing Q fever, is an obligate intracellular biosafety level 3 agent. Detection and quantification of these bacteria with conventional methods is time consuming and dangerous. ...
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2015-10-26ZeitschriftenartikelInteractions between Hepatitis C Virus and the Human Apolipoprotein H Acute Phase Protein: A Tool for a Sensitive Detection of the Virus Stefas, Ilias; Tigrett, Sylvia; Dubois, Grégor; Kaiser, Marco; Lucarz, Estelle; Gobby, Delphine; Bray, Dorothy; Ellerbrok, Heinz; Zarski, Jean Pierre; Veas, FranciscoThe Hepatitis C virus (HCV) infection exhibits a high global prevalence frequently associated with hepatocellular carcinoma, taking years to develop. Despite the standardization of highly sensitive HCV quantitative RT-PCR ...
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2008-05-28ZeitschriftenartikelInterspecies transmission of simian foamy virus in a natural predator-prey system Leendertz, Fabian; Zirkel, Florian; Couacy-Hymann, Emmanuel; Ellerbrok, Heinz; Morozov, Vladimir; Pauli, Georg; Hedemann, Claudia; Formenty, Pierre; Jensen, Siv Aina; Boesch, Christophe; Junglen, SandraSimian foamy viruses (SFV) are ancient retroviruses of primates and have coevolved with their host species for as many as 30 million years. Although humans are not naturally infected with foamy virus, infection is occasionally ...