Auflistung nach Schlagwort "Amino Acid Sequence"
Anzeige der Publikationen 1-20 von 27
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2009-11-09ZeitschriftenartikelA novel herpesvirus in the sanctuary chimpanzees on Ngamba Island in Uganda Background: Recent studies in non-human primates have led to the discovery of novel primate herpesviruses. In order to get more information on herpesvirus infections in apes, we studied wild born captive chimpanzees. ...
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2013-06-12ZeitschriftenartikelAntibody Responses in Humans Infected with Newly Emerging Strains of West Nile Virus in Europe Infection with West Nile Virus (WNV) affects an increasing number of countries worldwide. Although most human infections result in no or mild flu-like symptoms, the elderly and those with a weakened immune system are at ...
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2002-07-31ZeitschriftenartikelAssociation of two newly recognized herpesviruses with interstitial pneumonia in donkeys (Equus asinus) Over a period of 6 years, antemortem and postmortem examinations were performed on a number of donkeys suffering from respiratory disease. For many cases, initial diagnostic efforts failed to identify an etiology consistent ...
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2012-12-26ZeitschriftenartikelBiological and Phylogenetic Characteristics of Yellow Fever Virus Lineages from West Africa The yellow fever virus (YFV), the first proven human-pathogenic virus, although isolated in 1927, is still a major public health problem, especially in West Africa where it causes outbreaks every year. Nevertheless, little ...
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2009-02-09ZeitschriftenartikelCharacterisation of porin genes from Mycobacterium fortuitum and their impact on growth Background: Highly pathogenic mycobacteria like Mycobacterium tuberculosis are characterised by their slow growth and their ability to reside and multiply in the very hostile phagosomal environment and a correlation ...
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2013-10-23ZeitschriftenartikelCytomegalovirus expresses the chemokine homologue vXCL1 capable of attracting XCR1+CD4- dendritic cells Cytomegaloviruses (CMV) have developed various strategies to escape the immune system of the host. One strategy involves the expression of virus-encoded chemokines to modulate the host chemokine network. We have identified ...
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2010-10-31ZeitschriftenartikelDirect Visualization of Peptide/MHC Complexes at the Surface and in the Intracellular Compartments of Cells Infected In Vivo by Leishmania major Protozoa and bacteria infect various types of phagocytic cells including macrophages, monocytes, dendritic cells and eosinophils. However, it is not clear which of these cells process and present microbial antigens in vivo ...
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2012-07-25ZeitschriftenartikelEastern Chimpanzees, but not Bonobos, Represent a Simian Immunodeficiency Virus Reservoir Chimpanzees in west central Africa (Pan troglodytes troglodytes) are endemically infected with simian immunodeficiency viruses (SIVcpzPtt) that have crossed the species barrier to humans and gorillas on at least five ...
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2007-05-25ZeitschriftenartikelFepA- and TonB-dependent bacteriophage H8: receptor binding and genomic sequence. H8 is derived from a collection of Salmonella enterica serotype Enteritidis bacteriophage. Its morphology and genomic structure closely resemble those of bacteriophage T5 in the family Siphoviridae. H8 infected S. enterica ...
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2013-04-22ZeitschriftenartikelFoodborne Transmission of Bovine Spongiform Encephalopathy to Nonhuman Primates Risk for human exposure to bovine spongiform encephalopathy (BSE)–inducing agent was estimated in a nonhuman primate model. To determine attack rates, incubation times, and molecular signatures, we orally exposed 18 macaques ...
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2009-04-22ZeitschriftenartikelGenetic variability of group A human respiratory syncytial virus strains circulating in Germany from 1998 to 2007. The variability between respiratory syncytial virus (RSV) strains is one of the features of RSV infections that might contribute to the ability of the virus to infect people repeatedly and cause yearly outbreaks. To study ...
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2005-01-24ZeitschriftenartikelGenetical and functional investigation of fliC genes encoding flagellar serotype H4 in wildtype strains of Escherichia coli and in a laboratory E. coli K-12 strain expressing flagellar antigen type H48 Background: Serotyping of O-(lipopolysaccharide) and H-(flagellar) antigens is a wideley used method for identification of pathogenic strains and clones of Escherichia coli. At present, 176 O- and 53 H-antigens are ...
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2011-02-16ZeitschriftenartikelHighly conserved serine residue 40 in HIV-1 p6 regulates capsid processing and virus core assembly Background: The HIV-1 p6 Gag protein regulates the final abscission step of nascent virions from the cell membrane by the action of two late assembly (L-) domains. Although p6 is located within one of the most polymorphic ...
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2010-01-13ZeitschriftenartikelHLA–B27 heavy chains distinguished by a micropolymorphism exhibit differential flexibility Objective: Although the products of the HLA subtypes B*2705 and B*2709 differ only in residue 116 (Asp versus His) within their peptide-binding grooves, they are differentially associated with inflammatory rheumatic ...
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2012-08-14ZeitschriftenartikelIsolation and characterization of three Mammalian orthoreoviruses from European bats. In recent years novel human respiratory disease agents have been described in South East Asia and Australia. The causative pathogens were classified as pteropine orthoreoviruses with strong phylogenetic relationship to ...
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2015-02-06ZeitschriftenartikelIsolation and Functional Characterization of the Novel Clostridium botulinum Neurotoxin A8 Subtype Botulism is a severe neurological disease caused by the complex family of botulinum neurotoxins (BoNT). Based on the different serotypes known today, a classification of serotype variants termed subtypes has been proposed ...
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2011-09-30ZeitschriftenartikelLife cycle stage-resolved proteomic analysis of the excretome/secretome from Strongyloides ratti - identification of stage-specific proteases. A wide range of biomolecules, including proteins, are excreted and secreted from helminths and contribute to the parasite's successful establishment, survival, and reproduction in an adverse habitat. Excretory and secretory ...
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2009-07-22ZeitschriftenartikelMeasles viruses of genotype H1 evade recognition by vaccine-induced neutralizing antibodies targeting the linear haemagglutinin noose epitope The linear haemagglutinin noose epitope (HNE; aa 379-410) is a protective B-cell epitope and considered to be highly conserved in both the vaccine and the wild-type measles virus (MeV) haemagglutinin (H) proteins. Vaccine ...
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2013-01-30ZeitschriftenartikelModulation of Cytokine Release and Gene Expression by the Immunosuppressive Domain of gp41 of HIV-1 The transmembrane envelope protein gp41 of the human immunodeficiency virus HIV-1 plays an important role during infection allowing fusion of the viral and cellular membrane. In addition, there is increasing evidence that ...
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2014-05-16ZeitschriftenartikelMolecular Epidemiology and Genotyping of Hepatitis B Virus of HBsAg-Positive Patients in Oman Background: Hepatitis B virus (HBV) infection is a major global health burden with distinct geographic public health significance. Oman is a country with intermediate HBV carrier prevalence; however, little is known ...