2014-05-21Zeitschriftenartikel
Lymph-borne CD8α+ dendritic cells are uniquely able to cross-prime CD8+ T cells with antigen acquired from intestinal epithelial cells
Cerovic, V.; Houston, S. A.; Westlund, J.; Utriainen, L.; Davison, E. S.; Scott, C. L.; Bain, C. C.; Joeris, T.; Agace, W. W.; Kroczek, Richard; Mowat, A. M.; Yrlid, U.; Milling, S. W. F.
Cross-presentation of cellular antigens is crucial for priming CD8+ T cells, and generating immunity to intracellular pathogens—particularly viruses. It is unclear which intestinal phagocytes perform this function in vivo. ...
