2010-01-20Zeitschriftenartikel
CRK adaptor protein expression is required for efficient replication of avian influenza A viruses and controls JNK-mediated apoptotic responses
Hrincius, Eike R.; Wixler, Viktor; Wolff, Thorsten; Wagner, Ralf; Ludwig, Stephan; Ehrhardt, Christina
The non-structural protein 1 (A/NS1) of influenza A viruses (IAV) harbours several src-homology domain (SH) binding motifs that are required for interaction with cellular proteins. The SH3 binding motif at aa212-217 [PPLPPK] ...