2013-02-28Zeitschriftenartikel
Macrophage-expressed IFN-β Contributes to Apoptotic Alveolar Epithelial Cell Injury in Severe Influenza Virus Pneumonia
Högner, Katrin; Wolff, Thorsten; Pleschka, Stephan; Plog, Stephanie; Gruber, Achim D.; Kalinke, Ulrich; Walmrath, Hans-Dieter; Bodner, Johannes; Gattenlöhner, Stefan; Lewe-Schlosser, Peter; Matrosovich, Mikhail; Seeger, Werner; Lohmeyer, Jürgen; Herold, Susanne
Influenza viruses (IV) cause pneumonia in humans with progression to lung failure and fatal outcome. Dysregulated release of cytokines including type I interferons (IFNs) has been attributed a crucial role in immune-mediated ...