Browsing by Subject "Polymorphism Genetic"
Now showing items 1-6 of 6
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2009-04-22ZeitschriftenartikelGenetic variability of group A human respiratory syncytial virus strains circulating in Germany from 1998 to 2007. The variability between respiratory syncytial virus (RSV) strains is one of the features of RSV infections that might contribute to the ability of the virus to infect people repeatedly and cause yearly outbreaks. To study ...
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2010-01-13ZeitschriftenartikelHLA–B27 heavy chains distinguished by a micropolymorphism exhibit differential flexibility Objective: Although the products of the HLA subtypes B*2705 and B*2709 differ only in residue 116 (Asp versus His) within their peptide-binding grooves, they are differentially associated with inflammatory rheumatic ...
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2012-02-09ZeitschriftenartikelOutbreak of salmonellosis after a wedding party, Bavaria, Germany, summer 2010: the importance of implementing food safety concepts An outbreak of salmonellosis in the summer of 2010 after a wedding party in Bavaria, Germany, was investigated, to identify vehicles and source of the outbreak and any flaws in food safety procedures. A cohort study ...
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2013-02-25ZeitschriftenartikelPredominance of HA-222D/G Polymorphism in Influenza A(H1N1)pdm09 Viruses Associated with Fatal and Severe Outcomes Recently Circulating in Germany Influenza A(H1N1)pdm09 viruses cause sporadically very severe disease including fatal clinical outcomes associated with pneumonia, viremia and myocarditis. A mutation characterized by the substitution of aspartic acid ...
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2015-08-27ZeitschriftenartikelTransmission patterns of human enterovirus 71 to, from and among European countries, 2003 to 2013 Enterovirus 71 (EV-71) is involved in epidemics of hand, foot, and mouth disease (HFMD) and has been reported to occur with severe neurological complications in eastern and south-east Asia. In other geographical areas, the ...
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2012-10-03ZeitschriftenartikelTreatment-associated polymorphisms in protease are significantly associated with higher viral load and lower CD4 count in newly diagnosed drug-naive HIV-1 infected patients Background: The effect of drug resistance transmission on disease progression in the newly infected patient is not well understood. Major drug resistance mutations severely impair viral fitness in a drug free environment, ...