Auflistung nach Schlagwort "XCR1"
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2012-07-18ZeitschriftenartikelExpression of XCR1 characterizes the Batf3-dependent lineage of dendritic cells capable of antigen cross-presentation Cross-presentation of antigen by dendritic cells (DCs) to CD8+ T cells is a fundamentally important mechanism in the defense against pathogens and tumors. Due to the lack of an appropriate lineage marker, cross-presenting ...
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2015-02-04ZeitschriftenartikelMouse conventional dendritic cells can be universally classified based on the mutually exclusive expression of XCR1 and SIRPα Since the identification of mouse dendritic cells (DC) in the early 70s, all attempts to consistently classify the identified functional DC subpopulations according to their surface molecule expression failed. In the absence ...
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2014-07-28ZeitschriftenartikelOntogenic, phenotypic, and functional characterization of XCR1+ dendritic cells leads to a consistent classification of intestinal dendritic cells based on the expression of XCR1 and SIRPα In the past, lack of lineage markers confounded the classification of dendritic cells (DC) in the intestine and impeded a full understanding of their location and function. We have recently shown that the chemokine receptor ...
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2018-12-13ZeitschriftenartikelStructure-Function Relationship of XCL1 Used for in vivo Targeting of Antigen Into XCR1+ Dendritic Cells XCL1 is the ligand for XCR1, a chemokine receptor uniquely expressed on crosspresenting dendritic cells (DC) in mouse and man. We are interested in establishing therapeutic vaccines based on XCL1-mediated targeting of ...
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2012-02-10ZeitschriftenartikelThe role of XCR1 and its ligand XCL1 in antigen cross-presentation by murine and human dendritic cells Recently, the chemokine receptor XCR1 has been found to be exclusively expressed on a subset of dendritic cell (DC) known to be involved in antigen cross-presentation. This review aims to summarize the known biology of the ...