2016-05-17Zeitschriftenartikel
Botulinum Neurotoxin Serotype A Recognizes Its Protein Receptor SV2 by a Different Mechanism than Botulinum Neurotoxin B Synaptotagmin
Weisemann, Jasmin; Stern, Daniel; Mahrhold, Stefan; Dorner, Brigitte; Rummel, Andreas
Botulinum neurotoxins (BoNTs) exhibit extraordinary potency due to their exquisite neurospecificity, which is achieved by dual binding to complex polysialo-gangliosides and synaptic vesicle proteins. The luminal domain 4 ...
