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2021-10-19Zeitschriftenartikel
Domestic risk factors for increased rodent abundance in a Lassa fever endemic region of rural Upper Guinea
dc.contributor.authorClark, Julia
dc.contributor.authorYakob, Laith
dc.contributor.authorDouno, Moussa
dc.contributor.authorLamine, Joseph
dc.contributor.authorMagassouba, N.'Faly
dc.contributor.authorFichet-Calvet, Elisabeth
dc.contributor.authorMarí Saéz, Almudena
dc.date.accessioned2024-08-12T14:41:27Z
dc.date.available2024-08-12T14:41:27Z
dc.date.issued2021-10-19none
dc.identifier.other10.1038/s41598-021-00113-z
dc.identifier.urihttp://edoc.rki.de/176904/11893
dc.description.abstractLassa fever (LF) is a viral haemorrhagic fever endemic in West Africa and spread primarily by the multimammate rat, Mastomys natalensis. As there is no vaccine, reduction of rodent-human transmission is essential for disease control. As the household is thought to be a key site of transmission, understanding domestic risk factors for M. natalensis abundance is crucial. Rodent captures in conjunction with domestic surveys were carried out in 6 villages in an area of rural Upper Guinea with high LF endemicity. 120 rodent traps were set in rooms along a transect in each village for three nights, and the survey was administered in each household on the transects. This study was able to detect several domestic risk factors for increased rodent abundance in rural Upper Guinea. Regression analysis demonstrated that having > 8 holes (RR = 1.8 [1.0004–3.2, p = 0.048), the presence of rodent burrows (RR = 2.3 [1.6–3.23, p = 0.000003), and being in a multi-room square building (RR = 2.0 [1.3–2.9], p = 0.001) were associated with increased rodent abundance. The most addressable of these may be rodent burrows, as burrow patching is a relatively simple process that may reduce rodent entry. Further study is warranted to explicitly link domestic rodent abundance to LF risk, to better characterize domestic risk factors, and to evaluate how household rodent-proofing interventions could contribute to LF control.eng
dc.language.isoengnone
dc.publisherRobert Koch-Institut
dc.rights(CC BY 3.0 DE) Namensnennung 3.0 Deutschlandger
dc.rights.urihttp://creativecommons.org/licenses/by/3.0/de/
dc.subjectanimal behavioreng
dc.subjectrisk factorseng
dc.subject.ddc610 Medizin und Gesundheitnone
dc.titleDomestic risk factors for increased rodent abundance in a Lassa fever endemic region of rural Upper Guineanone
dc.typearticle
dc.identifier.urnurn:nbn:de:0257-176904/11893-0
dc.type.versionpublishedVersionnone
local.edoc.container-titlescientific reportsnone
local.edoc.container-issn2045-2322none
local.edoc.pages10none
local.edoc.type-nameZeitschriftenartikel
local.edoc.container-typeperiodical
local.edoc.container-type-nameZeitschrift
local.edoc.container-urlhttps://www.nature.com/srep/none
local.edoc.container-publisher-nameSpringer Naturenone
local.edoc.container-volume11none
local.edoc.container-reportyear2021none
dc.description.versionPeer Reviewednone

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