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2018-10-17ZeitschriftenartikelWhat motivates Ebola survivors to donate plasma during an emergency clinical trial? The case of Ebola-Tx in Guinea Introduction During the 2014 Ebola Virus Disease (EVD) epidemic, the Ebola-Tx trial evaluated the use of convalescent plasma (CP) in Guinea. The effectiveness of plasmapheresis trials depends on the recruitment of plasma ...
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2018-11-06ZeitschriftenartikelRodent control to fight Lassa fever: Evaluation and lessons learned from a 4-year study in Upper Guinea Lassa fever is a viral haemorrhagic fever caused by an arenavirus. The disease is endemic in West African countries, including Guinea. The rodents Mastomys natalensis and Mastomys erythroleucus have been identified as Lassa ...
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2018-06-08ZeitschriftenartikelEducational inequalities in subjective health in Germany from 1994 to 2014: a trend analysis using the German Socio-Economic Panel study (GSOEP) Introduction As trend studies have shown, health inequalities by income and occupation have widened or remained stable. However, research on time trends in educational inequalities in health in Germany is scarce. The aim ...
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2018-04-12ZeitschriftenartikelGender inequalities in the association between area deprivation and perceived social support: a cross-sectional multilevel analysis at the municipality level in Germany Objectives To investigate the association between area deprivation at municipality level with low perceived social support, independent of individual socioeconomic position and demographic characteristics. To assess whether ...
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2018-10-02ZeitschriftenartikelOpportunistic HPV vaccination at age 16–23 and cervical screening attendance in Sweden: a national register-based cohort study Objectives To investigate whether cervical screening attendance differs between human papillomavirus (HPV)-vaccinated and unvaccinated women and to investigate potential underlying socioeconomic factors. Design Prospective ...
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2018-10-11ZeitschriftenartikelEffects of long-term methylphenidate use on growth and blood pressure: results of the German Health Interview and Examination Survey for Children and Adolescents (KiGGS) Background Concerns have been raised over the safety of methylphenidate (MPH), with regard to adverse effects on growth and blood pressure. Our study investigates whether, and to what extent, methylphenidate use in boys ...
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2018-06-15ZeitschriftenartikelDevelopment of Mobile Laboratory for Viral Hemorrhagic Fever Detection in Africa Background A mobile laboratory transportable on commercial flights was developed to enable local response to viral hemorrhagic fever outbreaks. Methods The development progressed from use of mobile real-time ...
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2018-10-01ZeitschriftenartikelProfiling antimicrobial peptides from the medical maggot Lucilia sericata as potential antibiotics for MDR Gram-negative bacteria Background The ability of MDR Gram-negative bacteria to evade even antibiotics of last resort is a severe global challenge. The development pipeline for conventional antibiotics cannot address this issue, but antimicrobial ...
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2019-03-05ZeitschriftenartikelImpact of health insurance status among migrants from sub-Saharan Africa on access to health care and HIV testing in Germany: a participatory cross-sectional survey Background Among all newly diagnosed HIV cases in Germany in 2015, 16% originated from sub-Saharan Africa. Twelve percent of these infections were contracted within Germany and migrants from sub-Saharan Africa (misSA) are ...
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2019-02-26ZeitschriftenartikelEmergence of the East-Central-South-African genotype of Chikungunya virus in Brazil and the city of Rio de Janeiro may have occurred years before surveillance detection Brazil, which is hyperendemic for dengue virus (DENV), has had recent Zika (ZIKV) and (CHIKV) Chikungunya virus outbreaks. Since March 2016, CHIKV is the arbovirus infection most frequently diagnosed in Rio de Janeiro. In ...
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2019-02-11ZeitschriftenartikelThe tyrosine transporter of Toxoplasma gondii is a member of the newly defined apicomplexan amino acid transporter (ApiAT) family Apicomplexan parasites are auxotrophic for a range of amino acids which must be salvaged from their host cells, either through direct uptake or degradation of host proteins. Here, we describe a family of plasma membrane-localized ...
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2019-01-11ZeitschriftenartikelA cross-sectional screening by next-generation sequencing reveals Rickettsia, Coxiella, Francisella, Borrelia, Babesia, Theileria and Hemolivia species in ticks from Anatolia Background Ticks participate as arthropod vectors in the transmission of pathogenic microorganisms to humans. Several tick-borne infections have reemerged, along with newly described agents of unexplored pathogenicity. ...
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2019-01-08ZeitschriftenartikelHIV-1 molecular transmission clusters in nine European countries and Canada: association with demographic and clinical factors Background Knowledge of HIV-1 molecular transmission clusters (MTCs) is important, especially in large-scale datasets, for designing prevention programmes and public health intervention strategies. We used a large-scale ...
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2018-12-29ZeitschriftenartikelFind the right sample: A study on the versatility of saliva and urine samples for the diagnosis of emerging viruses Background The emergence of different viral infections during the last decades like dengue, West Nile, SARS, chikungunya, MERS-CoV, Ebola, Zika and Yellow Fever raised some questions on quickness and reliability of ...
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2018-12-22ZeitschriftenartikelAntibiotic resistance, the 3As and the road ahead Antibiotic resistance is by far one of the most important health threats of our time. Only a global concerted effort of several disciplines based on the One-Health concept will help in slowing down this process and potentially ...
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2018-12-22ZeitschriftenartikelSepsis prediction during outbreaks at neonatal intensive care units through body surface screening for Gram-negative bacteria: systematic review and meta-analysis Objective This systematic review focusses on the prognostic accuracy of neonatal body surface screening during outbreaks caused by Gram-negative bacteria for prediction of sepsis. In a previous systematic review we reported ...
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2018-12-20ZeitschriftenartikelTime trends in depression prevalence and health-related correlates: results from population-based surveys in Germany 1997–1999 vs. 2009–2012 Background Although an “epidemic” of depression is frequently claimed, empirical evidence is inconsistent, depending on country, study design and depression assessment. Little is known about changes in depression over ...
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2018-12-12ZeitschriftenartikelParticipation in group-based physical activity programmes for adults in Germany and associated factors: data from a nationwide cohort study Background Characteristics of different participation groups can provide important information to increase participation in group-based physical activity programmes (GPAPs). This study examined four types of participation ...
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2018-12-18ZeitschriftenartikelAssociation between random glucose and all-cause mortality: findings from the mortality follow-up of the German National Health Interview and Examination Survey 1998 Background Random glucose is widely measured in epidemiological studies and in the clinical setting when standardized fasting protocols and oral glucose tolerance testing or HbA1c measuring are not feasible. The relationship ...
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2019-02-22ZeitschriftenartikelPositive predictive value of the German notification system for infectious diseases: Surveillance data from eight local health departments, Berlin, 2012 The German Infection Protection Act requires notifying certain cases of infectious diseases to local health departments (LHD) in Germany. LHDs transmit notifications meeting case definitions to the national health authority, ...