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2025-10-09ZeitschriftenartikelSyphilis in Deutschland in den Jahren 2023 und 2024 Die Syphilis ist eine durch Treponema pallidum verursachte Erkrankung, die nur beim Menschen vorkommt und sexuell, durch Blut und intrauterin von der Mutter auf das Kind übertragen wird. Sie verläuft typischerweise in drei ...
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2025-10-09ZeitschriftenartikelSaisonrückblick 2024/25 zu COVID-19, Influenza und RSV-Infektionen auf Grundlage der IfSG-Meldedaten – Ausbruchsgeschehen, Hospitalisierungen und Todesfälle im Fokus Die ARE-Saison 2024/25 startete in Woche 40/2024 auf dem Höhepunkt der COVID-19-Aktivität im Jahr 2024, welche jedoch im Vergleich zu den Vorjahren deutlich geringer ausfiel. Zum Jahreswechsel 2024/25 ging das ARE-Geschehen ...
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2023-01-09ZeitschriftenartikelNovel Plant-Associated Brevibacillus and Lysinibacillus Genomospecies Harbor a Rich Biosynthetic Potential of Antimicrobial Compounds We have previously reported the draft genome sequences of 59 endospore-forming Gram-positive bacterial strains isolated from Vietnamese crop plants due to their ability to suppress plant pathogens. Based on their draft ...
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2023-09-22ZeitschriftenartikelExploring HPV vaccine knowledge, attitudes, barriers and information sources among parents, health professionals and teachers in Kazakhstan: a mixed-methods study protocol Introduction: Human papillomavirus (HPV) is a prevalent sexually transmitted infection linked to certain types of malignant neoplasms, notably cervical cancer (CC). In Kazakhstan, a high prevalence of high oncogenic HPV ...
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2023-07-05ZeitschriftenartikelRelevance of Host Cell Surface Glycan Structure for Cell Specificity of Influenza A Viruses Influenza A viruses (IAVs) initiate infection via binding of the viral hemagglutinin (HA) to sialylated glycans on host cells. HA’s receptor specificity towards individual glycans is well studied and clearly critical for ...
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2023-08-02ZeitschriftenartikelPopulation-Based Clinical Cancer Registration in Germany Introduction: In 2013, a new federal law obligated all German federal states to collect additional clinical data in population-based cancer registries as an active tool for monitoring and improving the quality of cancer ...
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2023-10-25ZeitschriftenartikelForschung mit Krebsregistern – was geht, was (noch) nicht? Hintergrund: Eine der Aufgaben der Landeskrebsregister ist die Bereitstellung von Daten für Forschung oder eigene Forschung. Daten werden im Krebsregister nicht primär für Forschung, sondern mit Meldepflicht und ohne ...
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2022-11-21ZeitschriftenartikelInfluenza vaccine effectiveness against influenza A subtypes in Europe: Results from the 2021–2022 I-MOVE primary care multicentre study Background: In 2021–2022, influenza A viruses dominated in Europe. The I-MOVE primary care network conducted a multicentre test-negative study to measure influenza vaccine effectiveness (VE). Methods: Primary care ...
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2023-06-07ZeitschriftenartikelEnhancing global preparedness during an ongoing pandemic from partial and noisy data As the coronavirus disease 2019 spread globally, emerging variants such as B.1.1.529 quickly became dominant worldwide. Sustained community transmission favors the proliferation of mutated sub-lineages with pandemic ...
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2023-10-14ZeitschriftenartikelDifferential Transcriptional Responses of Human Granulocytes to Fungal Infection with Candida albicans and Aspergillus fumigatus Neutrophils are critical phagocytic cells in innate immunity, playing a significant role in defending against invasive fungal pathogens. This study aimed to explore the transcriptional activation of human neutrophils in ...
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2022-11-16ZeitschriftenartikelReply to Martin and Dauby
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2023-03-28ZeitschriftenartikelHighly contiguous genomes of human clinical isolates of Giardia duodenalis reveal assemblage- and sub-assemblage-specific presence–absence variation in protein-coding genes Giardia duodenalis (syn. G. intestinalis, G. lamblia) is a widespread gastrointestinal protozoan parasite with debated taxonomic status. Currently, eight distinct genetic sub-groups, termed assemblages A–H, are defined ...
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2023-06-15ZeitschriftenartikelFirst virological and pathological study of Göttingen Minipigs with Dippity Pig Syndrome (DPS) Dippity Pig Syndrome (DPS) is a well-known but rare complex of clinical signs affecting minipigs, which has not been thoroughly investigated yet. Clinically affected animals show acute appearance of red, exudating lesions ...
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2023-10-16ZeitschriftenartikelManaging and monitoring a pandemic: showcasing a practical approach for the genomic surveillance of SARS-CoV-2 With the rapidly growing amount of biological data, powerful but also flexible data management and visualization systems are of increasingly crucial importance. The COVID-19 pandemic has more than highlighted this need and ...
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2023-07-14ZeitschriftenartikelDevelopment of a prototype for high-frequency mental health surveillance in Germany: data infrastructure and statistical methods In the course of the COVID-19 pandemic and the implementation of associated non-pharmaceutical containment measures, the need for continuous monitoring of the mental health of populations became apparent. When the pandemic ...
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2023-04-21ZeitschriftenartikelThe Acinetobacter baumannii website (Ab-web): a multidisciplinary knowledge hub, communication platform, and workspace Acinetobacter baumannii is a Gram-negative bacterium increasingly implicated in hospital-acquired infections and outbreaks. Effective prevention and control of such infections are commonly challenged by the frequent emergence ...
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2023-08-22ZeitschriftenartikelNeighbourhood watch: genomic epidemiology of SARS-CoV-2 variants circulating in a German federal state, Mecklenburg-Western Pomerania, in 2020–2022 Global and even national genome surveillance approaches do not provide the resolution necessary for rapid and accurate direct response by local public health authorities. Hence, a regional network of microbiological ...
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2023-09-28ZeitschriftenartikelThe VBNC state: a fundamental survival strategy of Acinetobacter baumannii The viable but non-culturable (VBNC) state is a persistence strategy adopted by bacteria to withstand long-lasting periods of unfavorable conditions. VBNC cells evade classical detection methods and are therefore easily ...
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2023-02-10ZeitschriftenartikelDisease severity in hospitalized COVID-19 patients: comparing routine surveillance with cohort data from the LEOSS study in 2020 in Germany Introduction: Studies investigating risk factors for severe COVID-19 often lack information on the representativeness of the study population. Here, we investigate factors associated with severe COVID-19 and compare the ...
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2023-07-10ZeitschriftenartikelEx vivo infection model for Francisella using human lung tissue Introduction: Tularemia is mainly caused by Francisella tularensis (Ft) subsp. tularensis (Ftt) and Ft subsp. holarctica (Ftt) in humans and in more than 200 animal species including rabbits and hares. Human clinical ...