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2019-03-05ZeitschriftenartikelImpact of health insurance status among migrants from sub-Saharan Africa on access to health care and HIV testing in Germany: a participatory cross-sectional survey Background Among all newly diagnosed HIV cases in Germany in 2015, 16% originated from sub-Saharan Africa. Twelve percent of these infections were contracted within Germany and migrants from sub-Saharan Africa (misSA) are ...
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2019-02-26ZeitschriftenartikelEmergence of the East-Central-South-African genotype of Chikungunya virus in Brazil and the city of Rio de Janeiro may have occurred years before surveillance detection Brazil, which is hyperendemic for dengue virus (DENV), has had recent Zika (ZIKV) and (CHIKV) Chikungunya virus outbreaks. Since March 2016, CHIKV is the arbovirus infection most frequently diagnosed in Rio de Janeiro. In ...
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2019-02-11ZeitschriftenartikelThe tyrosine transporter of Toxoplasma gondii is a member of the newly defined apicomplexan amino acid transporter (ApiAT) family Apicomplexan parasites are auxotrophic for a range of amino acids which must be salvaged from their host cells, either through direct uptake or degradation of host proteins. Here, we describe a family of plasma membrane-localized ...
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2019-01-11ZeitschriftenartikelA cross-sectional screening by next-generation sequencing reveals Rickettsia, Coxiella, Francisella, Borrelia, Babesia, Theileria and Hemolivia species in ticks from Anatolia Background Ticks participate as arthropod vectors in the transmission of pathogenic microorganisms to humans. Several tick-borne infections have reemerged, along with newly described agents of unexplored pathogenicity. ...
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2019-01-08ZeitschriftenartikelHIV-1 molecular transmission clusters in nine European countries and Canada: association with demographic and clinical factors Background Knowledge of HIV-1 molecular transmission clusters (MTCs) is important, especially in large-scale datasets, for designing prevention programmes and public health intervention strategies. We used a large-scale ...
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2018-12-29ZeitschriftenartikelFind the right sample: A study on the versatility of saliva and urine samples for the diagnosis of emerging viruses Background The emergence of different viral infections during the last decades like dengue, West Nile, SARS, chikungunya, MERS-CoV, Ebola, Zika and Yellow Fever raised some questions on quickness and reliability of ...
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2018-12-22ZeitschriftenartikelAntibiotic resistance, the 3As and the road ahead Antibiotic resistance is by far one of the most important health threats of our time. Only a global concerted effort of several disciplines based on the One-Health concept will help in slowing down this process and potentially ...
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2018-12-22ZeitschriftenartikelSepsis prediction during outbreaks at neonatal intensive care units through body surface screening for Gram-negative bacteria: systematic review and meta-analysis Objective This systematic review focusses on the prognostic accuracy of neonatal body surface screening during outbreaks caused by Gram-negative bacteria for prediction of sepsis. In a previous systematic review we reported ...
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2018-12-20ZeitschriftenartikelTime trends in depression prevalence and health-related correlates: results from population-based surveys in Germany 1997–1999 vs. 2009–2012 Background Although an “epidemic” of depression is frequently claimed, empirical evidence is inconsistent, depending on country, study design and depression assessment. Little is known about changes in depression over ...
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2018-12-12ZeitschriftenartikelParticipation in group-based physical activity programmes for adults in Germany and associated factors: data from a nationwide cohort study Background Characteristics of different participation groups can provide important information to increase participation in group-based physical activity programmes (GPAPs). This study examined four types of participation ...
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2018-12-18ZeitschriftenartikelAssociation between random glucose and all-cause mortality: findings from the mortality follow-up of the German National Health Interview and Examination Survey 1998 Background Random glucose is widely measured in epidemiological studies and in the clinical setting when standardized fasting protocols and oral glucose tolerance testing or HbA1c measuring are not feasible. The relationship ...
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2019-02-22ZeitschriftenartikelPositive predictive value of the German notification system for infectious diseases: Surveillance data from eight local health departments, Berlin, 2012 The German Infection Protection Act requires notifying certain cases of infectious diseases to local health departments (LHD) in Germany. LHDs transmit notifications meeting case definitions to the national health authority, ...
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2019-02-14ZeitschriftenartikelCost-effectiveness and budget effect of pre-exposure prophylaxis for HIV-1 prevention in Germany from 2018 to 2058 Background Pre-exposure prophylaxis (PrEP) is a highly effective HIV prevention strategy for men-who-have-sex-with-men (MSM). The high cost of PrEP has until recently been a primary barrier to its use. In 2017, generic ...
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2019-02-14ZeitschriftenartikelPopulation size and self-reported characteristics and sexual preferences of men-who-have-sex-with-men (MSM) in Germany based on social network data Background In the absence of detailed information about the population size and behaviour data of men-who-have-sex-with-men (MSM), the estimation of prevalence rates of sexually transmitted infections (STIs) and the design ...
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2019-02-22ZeitschriftenartikelDetection of PCV3 in German wild boars Background Porcine circovirus 3 is a newly described circovirus circulating worldwide. PCV3 may play an etiologic role in different pig diseases. Two different genotypes of PCV3 were described, PCV3a and PCV3b. In order ...
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2018-02-22ZeitschriftenartikelUnterschiede in der subjektiven und psychischen Gesundheit und im Gesundheitsverhalten bei 11- bis 17-jährigen Jugendlichen an weiterführenden Schulen in Deutschland Ergebnisse der Studie zur Gesundheit von Kindern und Jugendlichen in Deutschland: Erste Folgebefragung (KiGGS Welle 1)Hintergrund Bereits im Kindes- und Jugendalter sind gesundheitliche Ungleichheiten zuungunsten sozial benachteiligter Bevölkerungsgruppen festzustellen. Der Beitrag untersucht, inwiefern sich Unterschiede in der subjektiven ...
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2019-02-07ZeitschriftenartikelAbsence of adaptive evolution is the main barrier against influenza emergence in horses in Asia despite frequent virus interspecies transmission from wild birds Virus ecology and evolution play a central role in disease emergence. However, their relative roles will vary depending on the viruses and ecosystems involved. We combined field studies, phylogenetics and experimental ...
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2019-02-07ZeitschriftenartikelAnalysis of long non-coding RNA and mRNA expression in bovine macrophages brings up novel aspects of Mycobacterium avium subspecies paratuberculosis infections Paratuberculosis is a major disease in cattle that severely affects animal welfare and causes huge economic losses worldwide. Development of alternative diagnostic methods is of urgent need to control the disease. Recent ...
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2019-01-08ZeitschriftenartikelHistory of detention and the risk of hepatitis C among people who inject drugs in Germany Objectives The aim of this study was to investigate the association between detention experience and hepatitis C virus (HCV) status, the role of duration and frequency of detention, and whether risk behaviours practiced ...
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2018-01-26ZeitschriftenartikelRegionale Unterschiede der Entwicklung der Krankenhausbehandlungen Effekt unterschiedlicher demografischer Trends?Demografische Alterung und Rückgang oder Schrumpfung der Bevölkerungszahl in vielen Gebieten der Bundesrepublik Deutschland sind Kernelemente des demografischen Wandels. Für die betroffenen Regionen ergibt sich eine sinkende ...