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2020-12-19ZeitschriftenartikelIn Vitro Evaluation of a Phage Cocktail Controlling Infections with Escherichia coli Worldwide, poultry industry suffers from infections caused by avian pathogenic Escherichia coli. Therapeutic failure due to resistant bacteria is of increasing concern and poses a threat to human and animal health. This ...
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2020-05-11ZeitschriftenartikelEAACI Task force Clinical epidemiology of anaphylaxis: experts' perspective on the use of adrenaline autoinjectors in Europe Background Worldwide, guidelines recommend the use of adrenaline autoinjectors (AAIs) for self-medication in patients who experience severe allergic reaction. The European Medical Agency recommends the prescription of ...
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2020-08-07ZeitschriftenartikelSpectrum of antibiotic resistant bacteria and fungi isolated from chronically infected wounds in a rural district hospital in Ghana Background Chronic infected wounds are generally difficult to manage and treatment can be particularly challenging in resource-limited settings where diagnostic testing is not readily available. In this study, the ...
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2020-06-25ZeitschriftenartikelRapid spread of OXA-244-producing Escherichia coli ST38 in Germany: insighta from an integrated molecular surveillance approach; 2017 to January 2020 Annually, increasing numbers of OXA-244-producing Escherichia coli in 13 German federal states prompted us to initiate an outbreak investigation. Whole genome sequencing revealed that among 148 isolates analysed, most ...
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2020-10-09ZeitschriftenartikelPrediction of child and adolescent outcomes with broadband and narrowband dimensions of internalizing and externalizing behavior using the child and adolescent version of the Strengths and Difficulties Questionnaire The Strengths and Difficulties Questionnaire (SDQ) is a frequently used screening instrument for behavioral problems in children and adolescents. There is an ongoing controversy—not only in educational research—regarding ...
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2020-02-18ZeitschriftenartikelThe Human Cytomegalovirus pUL145 Isoforms Act as Viral DDB1-Cullin-Associated Factors to Instruct Host Protein Degradetion to Impede Innate Immunity Human cytomegalovirus (HCMV) causes diseases in individuals with immature or compromised immunity. To evade immune control, HCMV evolved numerous antagonists targeting the interferon system at multiple levels. By comparative ...
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2020-04-04ZeitschriftenartikelS3 guideline for actinic keratosis and cutaneous squamous cell carcinoma (cSCC) – short version, part 2: epidemiology, surgical and systemic treatment of cSCC, follow-up, prevention and occupational disease Actinic keratoses (AKs) are common lesions in light-skinned individuals that can potentially progress to cutaneous squamous cell carcinoma (cSCC). Both conditions may be associated with significant morbidity and constitute ...
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2020-02-27ZeitschriftenartikelOnline Survey for the Assessment of Generic Health Literacy among Adolescents in Germany (GeKoJu): Study Protocol The promotion of health literacy at a young age can protect, maintain and improve health across the life course. Yet to date, a sound data basis on adolescent health literacy as a requirement for the development of strategies ...
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2020-04-21ZeitschriftenartikelDevelopment and Psychometric Properties of a Questionnaire Assessing Self-Reported Generic Health Literacy in Adolescence Health literacy is a promising approach to promoting health and preventing disease among children and adolescents. Promoting health literacy in early stages of life could contribute to reducing health inequalities. However, ...
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2020-11-19ZeitschriftenartikelThe civil society monitoring of hepatitis C respose related to the WHO 2030 elimination gals in 35 European countries Background People who inject drugs (PWID) account for the majority of new cases of hepatitis C virus (HCV) infection in Europe; however, HCV testing, and treatment for PWID remain suboptimal. With the advent of direct ...
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2020-01-16ZeitschriftenartikelCo-circulation of multiple enterovirus D68 subclades, including a novel B3 cluster, across Europe in a season of expected low prevalence, 2019/20 Enterovirus D68 (EV-D68) was detected in 93 patients from five European countries between 1 January 2019 and 15 January 2020, a season with expected low circulation. Patients were primarily children (n = 67, median age: 4 ...
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2020-10-30ZeitschriftenartikelGeographically structured genomic diversity of non-human primate-infecting Treponema pallidum subsp. pertenue Many non-human primate species in sub-Saharan Africa are infected with Treponema pallidum subsp. pertenue , the bacterium causing yaws in humans. In humans, yaws is often characterized by lesions of the extremities and ...
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2020-06-30ZeitschriftenartikelProfiling for Bioactive Peptides and Volatiles of Plant Growth Promoting Strains of Bacillus subtilis Complex of Industrial Relevance Plant growth promoting rhizobacteria attain increasing importance in agriculture as biofertilizers and biocontrol agents. These properties significantly depend on the formation of bioactive compounds produced by such ...
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2020-06-24ZeitschriftenartikelComprehensive integrated NGS-based surveillance and contact-network modeling unravels transmission dynamics of vancomycin-resistant enterococci in a high-risk population within a tertiary care hospital Vancomycin-resistant E. faecium (VRE) are an important cause of nosocomial infections, which are rapidly transmitted in hospitals. To identify possible transmission routes, we applied combined genomics and contact-network ...
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2026-09-24ZeitschriftenartikelJährlich wiederkehrende Ausbrüche durch Salmonella Strathcona in Deutschland – hohe Fallzahlen in der Saison 2025/2026 Im Jahr 2011 wurde Salmonella Strathcona erstmals im Rahmen eines multinationalen Ausbruchs in Europa identifiziert. Seitdem werden europaweit wiederholt Ausbrüche mit S. Strathcona beobachtet, deren Umfang im Laufe der ...
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2026-09-24ZeitschriftenartikelRKI-Ratgeber Humane Papillomvirus-assoziierte Erkrankungen Infektionen mit Humanen Papillomviren gehören in Deutschland (und weltweit) zu den häufigsten sexuell übertragbaren Infektionen. Schätzungen zufolge infizieren sich über 80 % der sexuell aktiven Menschen im Laufe ihres ...
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2020-09-03ZeitschriftenartikelGenome sequences of two clinical Escherichia coli isolates harboring the novel colistin-resistance gene variants mcr-1.26 and mcr-1.27 Background Colistin is still a widely used antibiotic in veterinary medicine although it is a last-line treatment option for hospitalized patients with infections caused by multidrug-resistant Gram-negative bacteria. ...
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2020-10-13ZeitschriftenartikelDiversity of Noroviruses throughout Outbreaks in Germany 2018 Human norovirus accounts for the majority of viral gastroenteritis cases worldwide. It is a fast evolving virus generating diversity via mutation and recombination. Therefore, new variants and new recombinant strains emerge ...
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2020-01ZeitschriftenartikelHuman activities link fruit bat presence to Ebola virus disease outbreaks A significant link between forest loss and fragmentation and outbreaks of Ebola virus disease (EVD) in humans has been documented. Deforestation may alter the natural circulation of viruses and change the composition, ...
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2020-07-15ZeitschriftenartikelDescription of Sarcocystis scandentiborneensis sp. nov. from treeshrews (Tupaia minor, T. tana) in northern Borneo with annotations on the utility of COI and 18S rDNA sequences for species delineation Sarcocystis scandentiborneensis sp. nov. was discovered in histological sections of striated musculature of treeshrews (Tupaia minor, T. tana) from Northern Borneo. Sarcocysts were cigar-shaped, 102 μm–545 μm long, and on ...