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2021-10-01Zeitschriftenartikel
Emergence and spread of SARS-CoV-2 lineage B.1.620 with variant of concern-like mutations and deletions
dc.contributor.authorDudas, Gytis
dc.contributor.authorHong, Samuel L.
dc.contributor.authorPotter, Barney I.
dc.contributor.authorCalvignac-Spencer, Sébastien
dc.contributor.authorNiatou-Singa, Frédéric S.
dc.contributor.authorTombolomako, Thais B.
dc.contributor.authorFuh-Neba, Terence
dc.contributor.authorVickos, Ulrich
dc.contributor.authorUlrich, Markus
dc.contributor.authorLeendertz, Fabian H.
dc.contributor.authorKhan, Kamran
dc.contributor.authorHuber, Carmen
dc.contributor.authorWatts, Alexander
dc.contributor.authorOlendraitė, Ingrida
dc.contributor.authorSnijder, Joost
dc.contributor.authorWijnant, Kim N.
dc.contributor.authorBonvin, Alexandre M.J.J.
dc.contributor.authorMartres, Pascale
dc.contributor.authorBehillil, Sylvie
dc.contributor.authorAyouba, Ahidjo
dc.contributor.authorFoudi-Maïdadi, Martin
dc.contributor.authorMeta-Djomsi, Dowbiss
dc.contributor.authorGowde, Celestin
dc.contributor.authorButel, Christelle
dc.contributor.authorŠimaitis, Aistis
dc.contributor.authorGabrielaitė, Miglė
dc.contributor.authorKatėnaitė, Monika
dc.contributor.authorNorvilas, Rimvydas
dc.contributor.authorRaugaitė, Ligita
dc.contributor.authorKoyaweda, Giscard Wilfried
dc.contributor.authorKandou, Jephté Kaleb
dc.contributor.authorJonikas, Rimvydas
dc.contributor.authorNasvytienė, Inga
dc.contributor.authorŽemeckienė, Živilė
dc.contributor.authorGečys, Dovydas
dc.contributor.authorTamušauskaitė, Kamilė
dc.contributor.authorNorkienė, Milda
dc.contributor.authorVasiliūnaitė, Emilija
dc.contributor.authorŽiogienė, Danguolė
dc.contributor.authorTiminskas, Albertas
dc.contributor.authorŠukys, Marius
dc.contributor.authorŠarauskas, Mantas
dc.contributor.authorAlzbutas, Gediminas
dc.contributor.authorAmuri Aziza, Adrienne
dc.contributor.authorLusamaki, Eddy Kinganda
dc.contributor.authorMakangara Cigolo, Jean-Claude
dc.contributor.authorMuyembe Mawete, Francisca
dc.contributor.authorLofiko, Emmanuel Lokilo
dc.contributor.authorMbala-Kingebeni, Placide
dc.contributor.authorMuyembe-Tamfum, Jean-Jacques
dc.contributor.authorBelizaire, Marie Roseline Darnycka
dc.contributor.authorEssomba, René Ghislain
dc.contributor.authorOkomo Assoumou, Marie Claire
dc.contributor.authorMboringong, Akenji Blaise
dc.contributor.authorDieng, Alle Baba
dc.contributor.authorJouzapaitė, Dovilė
dc.contributor.authorHosch, Salome
dc.contributor.authorObama, Justino
dc.contributor.authorOndo'o Ayekaba, Mitoha
dc.contributor.authorNaumovas, Daniel
dc.contributor.authorPautienius, Arnoldas
dc.contributor.authorRafaï, Clotaire Donatien
dc.contributor.authorVitkauskienė, Astra
dc.contributor.authorUgenskienė, Rasa
dc.contributor.authorGedvilaitė, Alma
dc.contributor.authorČereškevičius, Darius
dc.contributor.authorLesauskaitė, Vaiva
dc.contributor.authorŽemaitis, Lukas
dc.contributor.authorGriškevičius, Laimonas
dc.contributor.authorBaele, Guy
dc.date.accessioned2024-08-13T11:32:09Z
dc.date.available2024-08-13T11:32:09Z
dc.date.issued2021-10-01none
dc.identifier.other10.1038/s41467-021-26055-8
dc.identifier.urihttp://edoc.rki.de/176904/11899
dc.description.abstractDistinct SARS-CoV-2 lineages, discovered through various genomic surveillance initiatives, have emerged during the pandemic following unprecedented reductions in worldwide human mobility. We here describe a SARS-CoV-2 lineage - designated B.1.620 - discovered in Lithuania and carrying many mutations and deletions in the spike protein shared with widespread variants of concern (VOCs), including E484K, S477N and deletions HV69Δ, Y144Δ, and LLA241/243Δ. As well as documenting the suite of mutations this lineage carries, we also describe its potential to be resistant to neutralising antibodies, accompanying travel histories for a subset of European cases, evidence of local B.1.620 transmission in Europe with a focus on Lithuania, and significance of its prevalence in Central Africa owing to recent genome sequencing efforts there. We make a case for its likely Central African origin using advanced phylogeographic inference methodologies incorporating recorded travel histories of infected travellerseng
dc.language.isoengnone
dc.publisherRobert Koch-Institut
dc.rights(CC BY 3.0 DE) Namensnennung 3.0 Deutschlandger
dc.rights.urihttp://creativecommons.org/licenses/by/3.0/de/
dc.subjectmolecular evolutioneng
dc.subjectpathogenseng
dc.subjectphylogeneticseng
dc.subjectviral infectioneng
dc.subject.ddc610 Medizin und Gesundheitnone
dc.titleEmergence and spread of SARS-CoV-2 lineage B.1.620 with variant of concern-like mutations and deletionsnone
dc.typearticle
dc.identifier.urnurn:nbn:de:0257-176904/11899-6
dc.type.versionpublishedVersionnone
local.edoc.container-titleNature Communicationsnone
local.edoc.container-issn2041-1723none
local.edoc.pages12none
local.edoc.type-nameZeitschriftenartikel
local.edoc.container-typeperiodical
local.edoc.container-type-nameZeitschrift
local.edoc.container-urlhttps://www.nature.com/ncomms/none
local.edoc.container-publisher-nameSpringer Naturenone
local.edoc.container-volume12none
local.edoc.container-reportyear2021none
dc.description.versionPeer Reviewednone

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