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2021-03-16Zeitschriftenartikel
Screening for common eye diseases in the elderly with Optos ultra-wide-field scanning laser ophthalmoscopy: a pilot study with focus on ocular toxoplasmosis
dc.contributor.authorLogroño Wiese, Pablo Eduardo
dc.contributor.authorSeeber, Frank
dc.contributor.authorEndres, Anne-Sophie
dc.contributor.authorBrockmann, Claudia
dc.contributor.authorPleyer, Uwe
dc.date.accessioned2024-08-14T13:27:57Z
dc.date.available2024-08-14T13:27:57Z
dc.date.issued2021-03-16none
dc.identifier.other10.1007/s10792-020-01683-z
dc.identifier.urihttp://edoc.rki.de/176904/11924
dc.description.abstractPurpose Studies on the occurrence of ocular toxoplasmosis (OT) in a general population are rare. Therefore, we conducted this pilot study to assess whether a nonmydriatic ultra-wide-field (UWF) scanning laser ophthalmoscope (SLO) is suitable for a simple, rapid screening procedure. Methods The population of this cross-sectional study was randomly recruited from a cohort of hospital-based patients in an urban geriatric hospital. Ophthalmologic evaluation was performed on 201 eyes from 101 participants through nonmydriatic UWF-SLO (Optos Daytona) and assessed for suspicious lesions and other relevant ocular findings. All images were evaluated by two independent examiners. Individuals who presented lesions with a morphological appearance suggestive of OT underwent fundoscopy and serological analysis of Toxoplasma gondii-specific antibodies. Results The mean age of the study group was 76 years, and 63 (62%) were female. Despite many health restrictions, the SLO examination was carried out easily in this geriatric population. Three participants presented findings by SLO suspicious for T. gondii-related injury. Further clinical examination and serological investigation confirmed the diagnosis, with funduscopic evaluation and positive T. gondii ELISA testing. In addition, a high rate of arterial hypertension and dyslipidemias within the cohort led to a high incidence of vascular changes and age-related fundus findings. Conclusion In our study, we confirm that UWF-SLO technology is helpful in the rapid detection of peripheral retinal injuries in elderly patients such as OT and may be used as a routine screening tool.eng
dc.language.isoengnone
dc.publisherRobert Koch-Institut
dc.rights(CC BY 3.0 DE) Namensnennung 3.0 Deutschlandger
dc.rights.urihttp://creativecommons.org/licenses/by/3.0/de/
dc.subjectgeriatric screeningeng
dc.subjectocular toxoplasmosiseng
dc.subjectt.gondiieng
dc.subjectultra-wide-field scanning laser ophtalmoscopyeng
dc.subject.ddc610 Medizin und Gesundheitnone
dc.titleScreening for common eye diseases in the elderly with Optos ultra-wide-field scanning laser ophthalmoscopy: a pilot study with focus on ocular toxoplasmosisnone
dc.typearticle
dc.identifier.urnurn:nbn:de:0257-176904/11924-8
dc.type.versionpublishedVersionnone
local.edoc.container-titleInternational Ophtalmologynone
local.edoc.container-issn1573-2630none
local.edoc.pages12none
local.edoc.type-nameZeitschriftenartikel
local.edoc.container-typeperiodical
local.edoc.container-type-nameZeitschrift
local.edoc.container-urlhttps://link.springer.com/journal/10792none
local.edoc.container-publisher-nameSpringer Naturenone
local.edoc.container-volume41none
local.edoc.container-reportyear2021none
local.edoc.container-firstpage1573none
local.edoc.container-lastpage1584none
dc.description.versionPeer Reviewednone

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